5 Tips for Living Well With Multiple Myeloma
Published on June 9, 2026
Because multiple myeloma is a chronic condition that follows a relapsing-remitting pattern, the goal isn’t to return to your life before diagnosis. Instead, it’s about creating a “new normal” that supports your quality of life over the long run.
Finding your new normal can take time, but it starts with small steps that can support your physical and emotional well‑being.
1. Prioritize Bone Health
Bone disease is one of the most common symptoms of multiple myeloma, affecting approximately 85 percent of people. “This occurs because myeloma cells essentially try to eat away the bones, causing them to break down much faster than they can be rebuilt,” says Rahul Gosain, MD, the medical director of the University of Rochester’s Wilmot Cancer Institute in Webster, New York.
When bone breaks down faster than it can be repaired, it can lead to several problems. Bones become thinner and weaker, and small holes (lytic lesions) can form within the bone, leading to pain, fractures, and compression on the spinal cord. Calcium is also released into the blood as bone breaks down, resulting in high calcium levels.
You can support your bone health in several ways.
- Use bone‑strengthening medications. Medications like bisphosphonates (Zometa or Aredia) or denosumab (Xgeva) can slow bone loss and lower your risk of fractures.
- Get enough vitamin D and calcium. Foods like fish, egg yolks, and dairy products are good sources. Your doctor may also recommend supplements if your levels are low. If you have kidney issues, talk to your doctor before starting these supplements or bone-strengthening medications.
- Stay active with low-impact exercise. Low-impact activities like walking, stationary biking, or swimming help keep your bones strong and reduce your risk of falls and fractures.
2. Eat to Support Your Immune System
Multiple myeloma and its treatments weaken the immune system, which makes it easier for your body to get infections. But eating well can give your body the nutrients it needs to keep your immune system functioning well.
A good place to start is to get enough protein in your diet. Your body uses protein to make antibodies and immune cells to fight infection. When you don’t eat enough protein, your body starts to break down muscle to meet its needs, which can lead to fatigue and loss of strength. Good sources include lean options like chicken, turkey, fish, beans, tofu, and soy.
Limiting highly processed foods and shifting your eating pattern toward a Mediterranean diet can also support the immune system. Diets high in sugar and unhealthy fats increase inflammation, which puts extra stress on the body. Instead, focus on eating whole foods like fruits, vegetables, whole grains, and fish. These foods provide vitamins and antioxidants to support immune function and keep inflammation at bay.
Lastly, choose foods that support a healthy gut. Good gut bacteria help your immune system by producing short-chain fatty acids that reduce inflammation. Foods like yogurt, kefir, and high-fiber foods are all great options to nourish these bacteria to support immune function.
3. Master the Art of Energy Conservation
Fatigue is a common challenge for people living with multiple myeloma. “Unlike normal tiredness, this fatigue lasts much longer because it is caused by both the cancer and its treatments,” says Rohit Gosain, MD, the medical director of hematology and oncology for the Roswell Park Care Network in Orchard Park, New York, and the brother of Dr. Rahul Gosain. But learning how to manage your energy throughout the day can help you make room for activities that are meaningful to you.
Start by focusing your energy on the most important tasks for the day and letting go of anything that can wait for tomorrow. This helps you save energy for the things that bring you joy. For physically demanding tasks like grocery shopping, carrying laundry, or cleaning the house, ask friends or family for help.
Instead of pushing through your fatigue, try spreading your activities throughout the day and alternating harder tasks with easier ones. You can also divide large tasks into small, manageable steps, so you can rest in between them. Taking these short breaks throughout the day helps you avoid running out of energy, so you can have energy for the activities you enjoy most.
4. Stay Physically Active
Although staying active with multiple myeloma can be challenging, exercise is one of the most effective ways to help you feel better and stay strong. Even a few minutes of movement each day can make a difference.
This is especially true when it comes to managing fatigue. “Staying active is one of the best ways to fight [cancer-related] fatigue. The more you move, the less fatigue you have,” says Dr. Gosain.
While resting may seem like the best thing to do when you’re tired, too much inactivity can actually make fatigue worse.
Exercise also protects your body from the physical effects of the disease. Since most people with multiple myeloma develop some degree of bone disease, weight-bearing activities like walking or light strength training strengthens your bones and lowers your risk of fractures. Staying active also helps preserve your muscle mass, which can be lost due to the disease itself or its treatments, such as steroids.
But its benefits can extend beyond your physical health. Regular movement can also ease the depression and anxiety that often accompany a chronic disease. It can also help you regain a sense of control during a time that may seem unpredictable.
5. Care for Your Mental Health
Cancer can be draining on your mental health, especially so in the case of multiple myeloma, which is difficult to cure completely. Between the lists of appointments, worries, and day-to-day living, it can be easy to become anxious or overwhelmed. A survivorship plan detailing your follow-up treatments and lifestyle recommendations may help you keep track of everything.
In addition, seek out an emotional support team — this can include friends, family, therapists, or cancer support groups. Your cancer care team can suggest some local resources.
Other ways to care for your mental health include:
- Journaling
- Exercising
- Meditating or practicing mindfulness
- Doing activities you enjoy
The Takeaway
- Living well with multiple myeloma involves establishing habits that support your long-term quality of life, including maintaining your bone health, eating a whole foods diet, managing your energy well, and keeping physically active.
- You can support your bone health by doing low-impact exercises, using bone-strengthening medications, and taking calcium or vitamin D supplements under your doctor's supervision.
- To manage your energy, prioritize tasks that matter the most, take frequent breaks between activities, and break tasks into smaller steps. Asking for help with physically demanding activities can also help you save energy for the things you enjoy.
- Staying active is one of the most important things you can do for your overall health. Regular movement helps you combat fatigue, strengthen your bones, preserve your muscle mass, and support your emotional well‑being.
EDITORIAL SOURCES
Everyday Health follows strict sourcing guidelines to ensure the accuracy of its content, outlined in our editorial policy. We use only trustworthy sources, including peer-reviewed studies, board-certified medical experts, patients with lived experience, and information from top institutions.
Resources
- Stallard J. Multiple Myeloma: Improved Prognosis With the Latest Treatments. Memorial Sloan Kettering Cancer Center. January 27, 2026.
- A Guide to Multiple Myeloma Bone Disease. International Myeloma Foundation. January 21, 2026.
- Bone Health and Multiple Myeloma: What You Need to Know. Multiple Myeloma Research Foundation. 2022.
- Vitamin D and Calcium. Johns Hopkins Medicine.
- Exercise and Myeloma. Myeloma Australia. September 2025.
- Multiple Myeloma Complications. International Myeloma Foundation. May 27, 2025.
- Benefits of Good Nutrition During Cancer Treatment. American Cancer Society. October 13, 2025.
- McDonald E. What Foods Cause or Reduce Inflammation? UChicago Medicine. September 4, 2020.
- Nutrition and Immunity. Harvard T.H. Chan School of Public Health The Nutrition Source.
- Ruo-Gu X et al. Health Benefits and Side Effects of Short-Chain Fatty Acids. Foods. September 15, 2022.
- Gingrasso A. Good Bacteria for Your Gut. Mayo Clinic Health System. April 23, 2025.
- Cancer-Related Fatigue. American Cancer Society. July 16, 2024.
- The 4 Ps: Strategies You Can Use to Cope With Fatigue. Arthritis UK.
- Dexamethasone. International Myeloma Foundation. June 23, 2025.
- How Exercise Can Help Manage Depression During Cancer. American Cancer Society. December 13, 2024.
- Living as a Multiple Myeloma Survivor. American Cancer Society. February 28, 2025.
- 10 Tips for Living Well With Multiple Myeloma. Cancer Support Community. July 2021.
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Walter Tsang, MD
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Walter Tsang, MD, is a board-certified medical oncologist, hematologist, and lifestyle medicine specialist. Inspired by the ancient Eastern philosophy of yang sheng ("nourishing li...
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