What Happened When I Took NAD+ Injections for a Month

For as long as I can remember, I’ve had a lot of energy. When I was in high school, I used to leap out of bed before my alarm, just champing at the bit to take on the day. That unbridled energy was strong throughout my twenties and even into my mid-thirties, but once I reached my late thirties and early forties, I began to notice a real dip. It suddenly felt much harder to get up in the morning. I started experiencing that midafternoon slump more and more, and I’d catch myself yawning often. Needless to say, I didn’t love the feeling, so I dove into research for a solution.

Most injectable NAD+ comes in a vial, so you have to use a new needle to measure out the amount every time you want a dose. This smart pen from Remedy Place makes the process much easier. It’s preloaded with 1,000 milligrams (mg) of NAD+, and you adjust the dosage by turning a dial on the pen. The brand suggests starting at 50 mg, but you can go up to 125 mg.

I loved that it came with everything I needed: alcohol swabs, an instruction booklet, a cute travel case, and more than enough needle heads, which were individually packaged so you can pop them onto the pen without risking getting poked. One caveat that I was initially unaware of was that you need to store the pen in the fridge when it arrives. Because this NAD+ is very high-grade and additive-free, customer service assured me mine was still safe to use, even though I’d left it out for about a week. But it’s a good rule of thumb with similar products to check temperature requirements.

The brand recommends starting with 50 mg every other day for the first week to help you acclimate to the product. I stuck with that for the whole month and never felt I needed more. The injection process took less than three minutes. I’d swab a spot on my lower abdomen with an alcohol pad, attach a packaged needle to the pen (twisting it slightly to pull the cap off), turn the dosage dial to 50 mg, and inject. Then I’d just twist off the needle using its packaging cap, toss it in the trash, and put the pen back in the fridge.

I barely felt the needle going in. The only slightly uncomfortable part was when I pushed the end of the pen to release the dose — there was a slight stinging feeling that lasted a few seconds as the dose dispersed into my bloodstream. But the benefits I felt almost immediately outweighed any minor discomfort.

Within 30 minutes, I had noticeably more energy that felt natural, never overwhelming or jittery. It had become a real challenge to will myself to work out at the end of the day. On NAD+, I was eager to do it and had more stamina. That energized feeling slowly declined at night, allowing me to fall asleep easily and stay asleep. And more benefits started kicking in around week three: My skin looked brighter and actually felt a bit thicker. I also felt like I was having fewer brain-fog moments (another lovely side effect of perimenopause). It wasn’t a night-and-day transformation, but it was enough to catch my attention.

See our full list of places to get NAD+ online here.