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13 Celebrities Who Have Spoken Out About Taking GLP-1s
GLP-1 medications are no longer Hollywood’s “worst kept secret.” From award-winning actors to sports icons, more and more celebrities are sharing how GLP-1 drugs like Ozempic, Wegovy, Zepbound, and Mounjaro have shaped their weight loss experiences.
Their honesty is helping to shift the conversation away from shame and toward real talk about managing weight and the impact it can have on all aspects of life, including physical and mental health.
Here are 15 well-known figures who’ve shared their GLP‑1 journeys — what worked, what didn’t, and how it’s changed them.
Oprah Winfrey

But she didn’t reveal one setback she’d had on her health journey. In a later interview with People, published in December 2025, Winfrey revealed that just six months after starting GLP-1s, she’d decided to see if she could “beat the medication” by stopping taking them. Her goal was to prove she could maintain the weight loss on her own.
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Serena Williams

“I knew my body was missing something it needed. For me, the answer was GLP-1s,” Williams said.
“I feel like I have a lot of energy and it’s great. I just feel pretty good about it,” said Williams.
Rebel Wilson

Whoopi Goldberg

Goldberg also discussed how all the constant chatter around people’s appearance can be harmful — and how everyone should be nicer to themselves and others. “Maybe the key is to stop judging everybody. Maybe that’s the key,” she said.
Charles Barkley

The former professional basketball star said he lost around 60 lb by taking Mounjaro, in addition to exercising and maintaining a healthy diet.
Kathy Bates

“It was hard work ... especially during the pandemic,” said Bates.
The actor also shared her plans to work out more, with activities like walking and Pilates, in order to maintain her weight loss.
Meghan Trainor

The “All About That Bass” singer and her husband, actor Daryl Sabara, took the lowest drug dose and combined the medication with exercise and balanced meals in a weight loss journey made for two.
The Grammy winner took to social media to respond to people who kept commenting on her transformation after her appearance at Billboard’s 2025 Women in Music Awards.
“No, I don’t look like I did 10 years ago. I’ve been on a journey to be the healthiest, strongest version of myself for my kids and for me. I’ve worked with a dietitian, made huge lifestyle changes, started exercising with a trainer, and yes, I used science and support (shoutout to Mounjaro!) to help me after my 2nd pregnancy. And I’m so glad I did because I feel great,” Trainor wrote on Instagram.
Billie Jean King

The 10-time Grand Slam winner spoke to actor Julia Louis-Dreyfus on the podcast Wiser Than Me about her decision to try a GLP-1.
“I’m a binge eater,” said the now 82-year-old King. “Every morning, I wake up, I tell myself I have an eating disorder. ... It’s interesting with the new injections, you know, with the Ozempics of the world. It’s very interesting because my doctor wants me to try it.”
Jim Gaffigan

Gaffigan is puzzled by the stigma around the medication, which is part of the reason he wanted to talk about it. “I don’t think there’s anything wrong with it. ... It’s just whatever gets you through,” he said.
Claudia Oshry

Elon Musk

The Tesla and SpaceX chief has said he wants to make the drug more accessible to all Americans, posting on X in 2024 that “nothing would do more to improve the health, lifespan, and quality of life for Americans” than making GLP-1s “super low cost to the public.”
Rosie O’Donnell

Tracy Morgan

Chelsea Handler

Surprisingly, the comedian didn’t know she was taking Ozempic when she first received a prescription, she said in an interview on the Call Her Daddy podcast. “My anti-aging doctor just hands it out to anybody,” Handler said. “I didn’t even know I was on it.”
Amy Schumer



