Supplements for GLP-1 Users: Dietitian Guide 2026

Taking a GLP-1 Medication? We Asked Dietitians Which Supplements Matter Most to Support Your Weight Loss Journey

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Glucagon-like peptide-1 receptor agonists (GLP-1s), such as Ozempic, Wegovy, and Zepbound, are well known for one major effect: They make it easier to eat less. By slowing digestion and enhancing fullness signals, these medications have been shown to reduce appetite.

From a nutrition standpoint, eating less isn’t automatically a problem. But if food intake drops too dramatically, it can become harder to meet your nutrient needs.

Studies show that people taking GLP-1s often consume substantially fewer calories, and many don’t get enough protein. In some cases, this has been linked to loss of lean muscle mass and vitamin and mineral deficiencies.

Dietitians will always recommend a food-first approach. Nutrient-dense meals and snacks provide not just vitamins and minerals but also fiber, protein, and beneficial plant compounds your body needs. But real life on a GLP-1 isn’t always ideal, especially early on, when your appetite drops, or when the side effects interfere with eating.

“The amount of nutrients a person typically needs in a day does not tend to differ much whether or not they are on a GLP-1 medication,” says Chelsea Leslie, RD, owner of Chelsea Rose Nutrition in Central Canada. “However, it is extremely important to have a strong focus on having a very nutrient-dense diet if on a GLP-1 [because] there is less opportunity to fit all the nutrients in.”

The goal for anyone on a GLP-1 is to eat enough food to meet their nutrient needs, but supplements may offer support. They aren’t a replacement for meals, but they can be a backup plan when food intake is inconsistent. In this guide, we break down the different nutrients dietitians most often discuss with GLP-1 users, including fiber, magnesium, electrolytes, protein, and other key vitamins, plus expert-recommended products to consider.

When to Consult a Doctor and Registered Dietitian

GLP-1 medications are meant to help regulate your appetite, not eliminate eating altogether. If you’re consistently skipping meals, struggling to tolerate food, or noticing nausea, vomiting, dizziness, or fatigue that won’t go away, it’s important to check in with a healthcare provider. These can be signs that your intake may not be adequately supporting your body’s needs.

Working with your doctor and a registered dietitian can help you manage side effects and maintain a healthy diet. While supplements can sometimes help fill gaps, they shouldn’t replace balanced meals.

Fiber to Help Keep Things Moving

Constipation is one of the most common side effects of taking GLP-1 medications. These drugs slow down how quickly food moves through the digestive system. Hydration, movement, and fiber are all foundational for keeping things regular, so when appetite drops, it can also impact daily bowel movements.

“While fiber can be consumed through the diet, the appetite-suppressing effects of GLP-1s can make it tricky to get in enough fiber, especially in the beginning as people are adjusting,” says Melissa Mitri, RD, nutrition writer and owner of Melissa Mitri Nutrition.

The reality is that most adults already fall short of the recommended fiber intake, so eating less only widens that gap.

“Many GLP-1 users have a hard time meeting the 25 or more grams of fiber per day. This can increase the risk of constipation and other common GI side effects,” says registered dietitian Ana Reisdorf, RD, founder and lead dietitian of GLP-1 Hub.

Fiber supplements can help fill gaps when your intake is inconsistent. Just make sure you don’t jump to a big dose of fiber all at once, especially if you’re just getting started. “Start low (3 to 5 grams a day) and titrate up slowly to avoid bloating,” advises Reisdorf. “Be sure to drink plenty of water if you are increasing fiber.”

fiber

Supergut GLP-1 Daily Support

“A supplement I like is the Supergut GLP-1 support; it comes in unflavored (so you can mix it into anything) or a variety of flavors,” says Reisdorf. It contains 6 grams of fiber from a blend of green banana fiber, oat beta-glucan, and soluble vegetable fiber.

Green banana fiber provides resistant starch, a prebiotic fiber that resists digestion and is fermented by the bacteria in your gut.

Beta-glucans are the soluble fiber found in oats that makes them so good for your heart and blood sugar.

With 6 grams of dietary of fiber, this product can help you reach your daily goals.

Mitri recommends psyllium fiber supplements for her clients until they can gradually meet a goal of 25 to 35 grams of fiber from food. We like organic India Psyllium Husk because it’s a simple, single-ingredient fiber supplement made from whole-husk psyllium, providing 4 grams of fiber per serving.

Psyllium is a soluble fiber known for helping to promote regularity and soften stool. Organic India’s version is unflavored and can easily be stirred into water, oatmeal, or smoothies.

As with any psyllium supplement, it’s important to start with a smaller amount, increase gradually, and drink plenty of fluids to reduce the risk of overdoing it.

Garden of Life Organic Fiber provides 5 grams of fiber per serving from a blend of organic acacia fiber, orange peel, baobab fruit, apple peel, and cranberry fruit. Acacia fiber (also called arabic fiber) is a soluble, prebiotic fiber that I’ve found to cause less gas and bloating in my clients than some other fibers.

We like that this formula uses organic ingredients and contains no artificial additives. It’s also NSF Certified Gluten-Free, meaning the product has been independently tested to meet strict standards for gluten content. It’s flavorless, so you can add it to just about anything to help meet your daily fiber needs.

Probiotics to Support Gut Health

Probiotics are live bacteria that can support the gut microbiome, the community of microbes in the digestive tract that support digestion, immune function, and metabolism. While probiotics are naturally found in fermented foods like yogurt and kimchi, supplements offer a more concentrated source.

Just as fiber can help address common digestive changes when taking GLP-1 medications, probiotics may offer another supportive strategy to help with bloating, gas, and other GI side effects for some people.

“Digestive health is often affected by dietary changes and medication side effects of GLP-1s, and it is important to always consider how to support your gut microbiome,” says Leslie. While there isn’t a lot of research on probiotics and GLP-1 symptoms, they may help support digestive balance as the body adjusts.
Interestingly, researchers are also exploring how GLP-1 medications themselves may influence the gut microbiome. Some evidence suggests that GLP-1s may positively affect healthy gut bacteria, though more research is needed.

Not everyone taking a GLP-1 needs a probiotic supplement. Many people can support gut health by consuming fiber (which serves as fuel for beneficial bacteria) and fermented foods. But if low appetite or digestive symptoms make those foods harder to tolerate, a probiotic supplement may help.

Keep in mind that there are many types of probiotics, and each strain offers different benefits, so it’s best to check with a healthcare provider to make sure you get the best product for your needs.

florastor select probiotic and fiber supplement

Florastor Dual Action Probiotic Supplement

Florastor probiotics contain a single-strain yeast-based probiotic called Saccharomyces boulardii, which has been well-studied for its positive effect on reducing diarrhea and gut inflammation while supporting healthy bacteria levels in the gut.

We like the simplicity of this product and how easy it is to find at online and local retailers. This specific strain of S. boulardii CNCM I-745 is found exclusively in this Florastor product (you can find other products with other types of S. boulardii  ), which adds to its credibility, as it’s been used in many studies.

prebiotic, probiotic

Jarrow Formulas Fem-Dophilus 1 Billion CFU

Jarrow’s Fem-Dophilus offers a specialized formula that targets not only digestive health but also vaginal and urinary health in women. Lacticaseibacillus rhamnosus GR-1 may help support vaginal flora and reduce the risk of urinary tract infections.

Limosilactobacillus reuteri RC-14 may also support vaginal health and influence the balance of healthy gut bacteria.

We like that this product is shelf-stable, so there is no need for refrigeration, and all Jarrow products follow a rigorous in-house testing process for quality control.

prebiotic, probiotic

SFI Health Ther-Biotic Synbiotic

If you aren’t sure what type of probiotic you need, or you are just looking for a high-quality option that offers an array of evidence-based bacterial strains, SFI’s Ther-Biotic Synbiotic is a favorite. It contains multiple lactobacillus and bifidobacteria strains, two groups of beneficial bacteria commonly studied for their digestive health benefits.

This product also contains Sunfiber, a prebiotic fiber that helps feed beneficial gut bacteria. The combination of prebiotic fiber plus probiotics is what makes this a synbiotic formula, designed to be an all-in-one option for supporting gut health. Sunfiber may help support digestive regularity, including relief from constipation and diarrhea.

Magnesium for Relaxation and Regularity

Magnesium is a mineral involved in hundreds of processes in the body, including muscle function, blood sugar regulation, healthy blood pressure, and digestion.

For people taking GLP-1 medications, magnesium supplements may help with constipation or provide additional support for sleep and stress.

When constipation is your primary concern, certain forms may be particularly helpful. “Magnesium, particularly magnesium citrate, can be effective for relieving GLP-1-related constipation and is supportive of muscle health,” says Mitri. Magnesium citrate works in part by drawing water into the stool, which can help promote bowel movements.

Magnesium supplements can also support overall dietary adequacy, since many adults don’t meet the recommended intake levels (between 310 and 420 milligrams of magnesium daily, depending on age). However, if you find yourself eating fewer of these foods due to low appetite or GI symptoms, a supplement may help.

magnesium

Now Foods Magnesium Citrate Powder

Now Foods Magnesium Citrate Powder offers 450 milligrams of magnesium citrate per teaspoon in an easy-to-mix format. Powdered magnesium can be especially useful if you don’t like swallowing pills, or if you want to easily adjust your dosage.

We like that this product contains only magnesium citrate, without additives or fillers. It’s also third-party tested, meaning it has been independently evaluated for purity and potential contaminants.

magnesium

Thorne Magnesium Bisglycinate

Thorne Magnesium Bisglycinate is a powdered magnesium supplement I personally use and recommend, especially for relaxation and sleep support.

It mixes easily, tastes good, and contains 200 milligrams of magnesium per scoop. Magnesium glycinate is bound to glycine, an amino acid that may promote feelings of calm. It’s also less likely to cause digestive upset, compared with some other types.

I often recommend Thorne for its high-quality, research-informed supplements and third-party testing standards. It’s also another powder form, so you can adjust your dose if needed.

magnesium

Pure Encapsulations Magnesium Citrate Capsule

For those who prefer capsules over powder, Pure Encapsulations Magnesium Citrate offers a simple solution. Each capsule provides 150 milligrams of magnesium citrate, without unnecessary fillers or artificial ingredients.

Pure Encapsulations is known for its high standards for quality and third-party testing. It’s also vegan and gluten-free.

Ritual offers a combination magnesium supplement that promotes both sleep and muscle relaxation. It contains magnesium bisglycinate for a calming effect, plus tart cherry, which increases melatonin levels. Melatonin is a hormone released in the evening in response to lower light levels that helps signal to your body that it’s time to sleep.

You can mix this tasty powder with water as part of your wind-down routine.

Multivitamins for Nutrient Gaps

A multivitamin is a helpful way to fill nutrient gaps when your appetite is suppressed and you’re not yet eating a truly balanced diet. “A multivitamin provides good peace of mind that you’re covering all your bases,” says Mitri. “When appetite is low on a GLP-1, and your diet may look different than usual, a multivitamin can help fill in the gaps to ensure you’re getting in all your essentials.”

Reisdorf points to newer research that found many GLP-1 users don’t get enough of certain vitamins and minerals, such as vitamin D, iron, calcium, thiamin, and B12, which can contribute to side effects like hair loss or fatigue while taking these medications.

“A multi provides some insurance against micronutrient deficiencies, improves energy, and supports hair health,” Reisdorf explains.

How do you know if you need a multivitamin? Mitri says that if you skip meals, skimp on whole foods, or experience digestive side effects that may interfere with nutrient absorption, it’s a sign you may need to supplement your diet. “If you have a diagnosed deficiency in multiple vitamins or minerals, a multivitamin can replenish what you need,” she says.

superfood gummies

Grüns Superfoods Greens Gummies

Grüns are multivitamin gummies with 20 vitamins and minerals, plus 6 grams of fiber, per serving. “I personally take Grüns because I like the gummy form, and they have additional fiber,” says Reisdorf. I’m right there with her. I love gummies, but don’t love the idea of sugar sitting on my teeth, which makes the sugar-free original and newer mango sorbet flavor feel like a treat.

Grüns are manufactured in facilities in the United States and Canada that are registered or compliant with NSF, Good Manufacturing Processes, and U.S. Food and Drug Administration standards. The company reports that each lot is tested for label accuracy, pesticides, heavy metals, and microbial contaminants, and that Eurofins Scientific, a respected testing company, provides third-party verification. Keep in mind that these don’t contain magnesium. That’s fairly common in multivitamins, since magnesium requires a larger dose and simply takes up too much space to fit into many standard formulas.

daily vits

Now Foods Daily Vits Multi Vitamin & Mineral

Now Foods Daily Vits Multi Vitamin & Mineral offers a budget-friendly option for covering your basic nutrient needs. The formula provides a range of essential vitamins and minerals, without unnecessary extras.

“Now Foods multivitamins are a quality choice, as they are thoroughly vetted and tested, are affordable, and of good quality,” Mitri notes. Like many multivitamins, this product does not contain iron (as not everyone needs it), and its magnesium content is relatively low. If you do need supplemental iron, you’ll likely need to get it from a separate product.

Pure Synergy Multi-Vita-Min is a whole–food–based multivitamin from a company I like for its quality standards and ingredient philosophy. Like the others in this category, this product doesn’t contain iron or magnesium, but it’s a good option to fill in the gaps until you can eat a more balanced diet.

Pure Synergy emphasizes organic, non-GMO ingredients and reports that its products undergo internal and third-party testing for contaminants like heavy metals and microbes.

ritual multivitamin women

Ritual Essential for Women 18+

Sometimes less is more, especially when it comes to multivitamins. For those who don’t need a multivitamin that includes as many nutrients, Ritual offers an option that provides essentials like vitamin D3 and iron. It also contains 330 milligrams of omega-3 fatty acids, which may support healthy inflammation levels.

If your intake is really low and you need a broader range of vitamins and minerals, this may not be the right choice. But if you eat a fairly balanced diet and only need to fill in a few nutrient options, Ritual is a convenient option.

Electrolytes for Hydration Support

Staying hydrated can be more challenging on GLP-1 medications than many people expect. Eating less often means lower intake of electrolytes like sodium and potassium, while side effects such as nausea, vomiting, or diarrhea can increase fluid and mineral losses.

You may also drink less simply because your body doesn’t recognize that you’re thirsty. “Research also shows GLP-1s can directly reduce our thirst sensation, where our brain doesn’t send us as many thirst signals throughout the day,” says Mitri.

“Taking electrolytes can hydrate you faster, help you retain the water you are consuming, and make you drink more.”
When choosing an electrolyte product, check the sodium content and overall ingredient quality, like added sugar (which is good if you’re running an endurance event, but not so much the rest of the time).

Some mixes contain more than 1,000 milligrams of sodium per serving, which again may be appropriate for athletes exercising in extreme heat, but is way too high for the average person, especially those with high blood pressure. For most nonathletes, keeping sodium below 140 milligrams per serving is a reasonable starting point, unless otherwise directed by a healthcare provider.

go hydrate packs

GoHydrate Electrolyte Drink Mix

GoHydrate is a flavored electrolyte powder with five electrolytes, including magnesium, calcium, phosphorus, and potassium. Its refreshing flavors, which are sweetened with stevia, can make it easier to drink more fluids throughout the day.

“I am loving the GoHydrate electrolytes at the moment. They are lower in sodium (only 80 milligrams), have five electrolytes, vitamin D, and they taste so good!” says Reisdorf. As a bonus, the 320 international units of vitamin D provides about half of the recommended amounts for adults.

liquid hydration

Liquid I.V. Hydration Multiplier Electrolyte Drink Mix

Liquid I.V. Hydration Multiplier offers slightly more sodium per serving (510 milligrams) than the others on our list. This can make it a helpful option for athletes, travel, or situations where fluid needs may be higher. It also provides B vitamins, which could be helpful for those who don’t get enough in their diet. Since this is high in sodium, keep an eye on your overall intake, so that you don’t go over the recommended 2,300 milligrams per day.

“Liquid I.V. is a good choice for daily hydration, and provides a solid dose of key electrolytes like sodium and potassium,” says Mitri. “They also offer many sugar-free flavors that are only 20 calories, helping you get in your electrolytes without unnecessary calories or added sugar.” Liquid I.V. also stands out for its wide variety of flavors, including classic citrus and fruit-based options.

electrolyte packs

Ultima Replenisher Daily Electrolyte Drink Mix

Ultima Replenisher is a great option if you’re looking for a variety of flavors with electrolytes like potassium, magnesium, calcium, and sodium, without added sugars. It also contains only 55 milligrams of sodium, making it appealing to those who want electrolyte support without a high sodium load. “Ultima Replenisher is also a solid choice that tastes great, and may be better for people with high blood pressure who need to watch their sodium intake,” says Mitri. I’ve also found that people who tend to be more sensitive to overly sweet electrolyte powders like the taste of this product.
electrolyte powder packets

IQBAR IQMIX Hydration + Clarity + Mood Mix

IQMIX powders offer another option for hydration, with a little extra benefit: Each stick contains electrolytes, B vitamins, and lion’s mane for energy and brain health support. Lion’s mane is a medicinal mushroom that’s been studied for its potential to support cognitive function and nerve health.

We like the extensive flavor selection, and that the type of magnesium included in this product (magnesium L-threonate) has the added benefit of potentially supporting mood and sleep.

Protein to Maintain Lean Muscle

Protein plays a key role in preserving lean muscle mass and maintaining strength during weight loss, but research suggests that meeting protein needs can be challenging while taking GLP-1s.

Leslie explains that protein is essential for a healthy metabolism, so a higher-protein diet paired with regular physical activity is an important strategy for protecting muscle during weight loss. But when GLP-1s do their job, you may feel full sooner and struggle to eat enough protein-rich foods.

While individual needs vary, most adults need 1 to 1.5 grams of protein per kilogram of body weight per day when taking a GLP-1.

“Protein is very important for [people taking] GLP-1s, and powders or drinks can make it easier to meet those needs on low-appetite days,” says Reisdorf. “I don’t think these are a must, as it is always best to get protein from food, but they are convenient.”
protein shake meal replacement

OWYN High-Protein Complete Nutrition Shakes

I love the convenience of OWYN High-Protein Complete Nutrition Shakes, with 26 grams of plant-based protein, in a ready-to-drink format. These smooth, vegan shakes have a mild chocolate flavor that isn’t overly sweet or chalky. The texture is lighter and thinner than many shakes, making it easy to drink on the go or when your appetite is flat.

Beyond protein, each bottle includes a greens blend with spinach, kale, and broccoli, plus 535 milligrams of omega-3s from flaxseed oil, and a range of added vitamins and minerals. While this nutrient-dense profile can be a bonus, you’ll want to check to make sure you aren’t getting too much if you also take a multivitamin.

whey protein

Naked Nutrition Grass-Fed Whey Protein Powder

Naked Nutrition Grass-Fed Whey Protein Powder offers a simple, minimal-ingredient option for meeting protein goals. “I love Naked Nutrition’s Whey protein powder for GLP-1 users,” says Mitri. “They have both unflavored and flavored versions that contain only 120 calories, 26 g of protein, and a clean label with minimum ingredients.” We especially like these options for those who prefer to make their protein shakes at home or mix the unflavored powder into yogurts or other foods to boost intake.
protein shakes

Quest Nutrition Protein Shake

Quest Nutrition’s ready-to-drink protein contains 30 grams of protein. The shake has a smooth texture and comes in several flavors, with a nutritional profile that is primarily protein with minimal fat and carbohydrates.

It also provides a notable amount of calcium, which may be a bonus if you aren’t getting enough. It is sweetened with sucralose, which is an artificial sweetener that some people prefer to avoid, but otherwise it’s a tasty option to help you fill those protein gaps.

Orgain 20g Plant-Based Protein Shake

Orgain’s protein shakes provide 20 grams of protein from pea protein. It’s dairy-free, and we like that it has a relatively short ingredient list, compared with some other ready-to-drink shakes.

It’s sweetened with monk fruit, so it offers a low sugar option without artificial sweeteners. It’s also creamy and convenient to sip on the go, which may make it easier to drink when your appetite is low or you need a quick protein source.

If you prefer making your own protein smoothies, Beam offers a tasty plant-based powder with 20 grams of pea protein isolate. It contains only 110 calories per serving, so you can either keep it simple as a snack or blend it with nut butter, chia seeds, and fruit to increase its nutrient density.

We also like that all Beam products are third-party tested, and you can enter your product’s lot number on the website to view its quality assurance certificate.

Vitamin D for Bones and Immune Health

Vitamin D is a common nutrient shortfall for many adults, as relatively few foods naturally contain meaningful amounts. Beyond supporting calcium absorption and bone health, vitamin D plays an important role in immune function and muscle health. The National Institutes of Health recommends about 600 to 800 international unites daily for most adults, depending on age.

“I always recommend a vitamin D supplement,” says Leslie. “Fortunately, our bodies can produce it, but it does require sunlight — and that can be difficult to get in the winter.” Recent research has found that vitamin D intake among GLP-1 users averages only about 20 percent of recommended levels.

“I would recommend getting levels checked first, but supplementing in winter months (if you live in a cold climate) can help improve intake,” Reisdorf says. Depending on your current vitamin D status, you may need more than the recommended amount to bring it up to a healthy level, so it’s helpful to know your baseline.

vitamin d

Carlson Liquid Vitamin D Super Daily D3

Carlson Super Daily D3 provides 1,000 international units of vitamin D3 in a simple liquid drop format. Just one drop delivers a full serving, which can be helpful for those who prefer not to swallow pills. The formula also contains MCT oil, a fat source that supports the absorption of vitamin D, a fat-soluble vitamin.

We like that the drops are tasteless and easy to take directly on your tongue or add to a glass of water or juice.

Nordic Naturals Vitamin D3 1000

Nordic Naturals Vitamin D3 1000 provides 1,000 international units of vitamin D3 in a single, easy-to-swallow capsule. I like it as a straightforward option for daily support of bone and immune health. It also includes olive oil to enhance absorption. Nordic Naturals is another company known for third-party testing to verify purity and potency.
Nature Made Calcium With D3 is a combination supplement designed to support bone health, providing 600 milligrams of calcium and 400 international units of vitamin D3. These nutrients work together, as vitamin D helps the body absorb and effectively use calcium.

This product is USP verified, meaning it has been independently tested by the United States Pharmacopeia for quality, purity, and potency.

How Can Supplements Support GLP-1 Users?

The benefit of appetite reduction feels like a positive change for many people using GLP-1s for weight loss, but eating significantly less can make it harder to meet daily protein, vitamin, and mineral needs.

Research shows that people taking GLP-1s can reduce their calorie intake by 16 to 39 percent.

When your overall intake drops too low, you increase the risk of falling short on nutrients your body needs for healthy functioning, such as iron, calcium, magnesium, zinc, and several vitamins, including vitamins A, D, E, K, B1 (thiamine), B12, and C.

GLP-1 digestion side effects can make this even more challenging because you simply don’t feel like eating.

I remind people that GLP-1 medications don’t lower your body’s nutrient requirements; they simply change how much you feel like eating. Supplements can help fill gaps when your appetite is low and you aren’t eating enough. That said, they’re meant to complement your diet, not replace real food. If you’re noticing unusual fatigue, hair loss, muscle weakness, or other changes that feel “off,” check in with your doctor or dietitian to develop a plan to make sure you get the nutrients you need.

Does Everyone Taking a GLP-1 Need Supplements?

Not everyone taking a GLP-1 medication develops nutrient deficiencies, and not everyone taking a GLP-1 needs supplements. That said, these medications can increase the risk of missing out on important nutrients.

“As a dietitian, I rarely recommend blanket supplements (i.e., everyone needs this!), but for the GLP-1 community, since their intake is decreased significantly, there are a few I do recommend,” says Reisdorf.

While GLP-1 medications don’t cause malabsorption of nutrients, reduced oral intake paired with the common GI symptoms raises the risk that you aren’t getting the vitamins and minerals you need.

Ultimately, supplement needs are individual. Factors like diet quality, side effects, lab values, and overall health all matter. If you’re eating very little, skipping meals, or experiencing persistent GI symptoms, a supplement may be a good idea.

What Nutrients Are Especially Important While Taking a GLP-1?

Several nutrients deserve closer attention when you’re on GLP-1 medications, but protein typically tops the list. “Protein is the single most critical nutrient for those on GLP-1s,” says Leslie. “Individuals on GLP-1s have a higher risk of dietary protein inadequacy. This can, unfortunately, result in increased muscle loss and subsequently increase the risk of malnutrition.”

Rapid weight loss has been associated with reductions in bone density, particularly in older adults and women. Adequate protein intake (along with calcium and vitamin D) and strength training may help support both muscle and bone health, but these are also nutrients you may not be getting enough of with a low-calorie diet.

Reduced food intake can also make it harder to meet recommended fiber targets, upping the risk of constipation. And fiber is not only important for digestive health — adequate fiber intake is associated with benefits for heart health and blood sugar control, both of which are especially relevant for people using GLP-1 medications.

Lower food intake may also contribute to missing out on nutrients such as vitamin D, B vitamins, magnesium, and iron.

FAQ

Are there any supplements I should avoid while taking GLP-1s?

Supplements aren’t without risks, especially if you have existing health conditions, take medication, or take multiple supplements that may overlap ingredients. “Avoid too many supplements — you really don’t need to take a bunch of different products,” says Reisdorf. “If you are also managing chronic diseases, speak to a doctor or dietitian before adding in supplements.”

There isn’t a single “best” option, as supplement needs depend on your individual nutrient levels and symptoms. Common recommendations include a multivitamin or a vitamin D supplement if your food intake drops.


Ideally, your diet should include a mix of soluble fiber (which dissolves in water and forms a gel that helps soften stool) and insoluble fiber (which adds bulk and helps move waste through your digestive tract). Foods like fruits, vegetables, beans, lentils, whole grains, nuts, and seeds naturally contain both.


“Magnesium is a very important mineral, and the reality is, as a population, we are just not getting enough,” says Leslie. Adults generally need between 310 and 420 milligrams daily, depending on age and sex.

Magnesium-rich foods include nuts and seeds, legumes, whole grains, leafy greens, and even dark chocolate.

 If appetite suppression makes it difficult to eat enough of these foods consistently, supplementation may help bridge the gap.

In some cases, certain supplements can help with GLP-1 side effects. For example, fiber may help with constipation, electrolytes with hydration, and magnesium with regularity. Supplements can support symptom management but should complement, not replace, food strategies.

No, supplements are designed to fill gaps but not replace a healthy diet. Prioritize nutrient-dense foods to meet protein, fiber, and overall nutrition needs. Supplements can support your diet or help when you aren’t able to eat enough.

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