Yartemlea (Intravenous)
Narsoplimab is used to treat thrombotic microangiopathy (TA-TMA) after a stem cell transplant in adults and children at least 2 years old.
Narsoplimab may also be used for purposes not listed in this medication guide.
uses
What is Yartemlea (Intravenous) used for?
- Hematopoietic Stem Cell Transplant-Associated Thrombotic Microangiopathy
warnings
What is the most important information I should know about Yartemlea (Intravenous)?
Tell your doctor if you have or have ever had:
- an active or recent infection.
Using narsoplimab may increase your risk of getting certain infections such as sepsis, pneumonia, viral or fungal infections, stomach or urinary tract infections, and bloodstream infections. Ask your doctor about your individual risk.
It is not known if narsoplimab will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.
Ask a doctor if it is safe to breastfeed while using this medicine.
Side Effects
What are the side effects of Yartemlea (Intravenous)?
Get emergency medical help if you have signs of an allergic reaction: hives, difficult breathing, swelling of your face, lips, tongue, or throat.
You may get infections more easily, even serious or fatal infections. Call your doctor right away if you have signs of infection such as:
- fever, chills, sore throat;
- mouth sores, red or swollen gums;
- upset stomach, diarrhea, vomiting;
- pale skin, easy bruising, unusual bleeding; or
- chest discomfort, wheezing, dry cough or hack, rapid weight loss.
Common side effects may include:
- infection;
- bleeding;
- nausea, vomiting, diarrhea;
- low white blood cell counts;
- low blood potassium; or
- fever, tiredness.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Pregnancy & Breastfeeding
Can I take Yartemlea (Intravenous) if I’m pregnant or breastfeeding?
It is not known if narsoplimab will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.
Ask a doctor if it is safe to breastfeed while using this medicine.
Interactions
What drugs and food should I avoid while taking Yartemlea (Intravenous)?
Follow your doctor's instructions about any restrictions on food, beverages, or activity.
Dosage Guidelines & Tips
How to take Yartemlea (Intravenous)?
Use Yartemlea (Intravenous) exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.
Narsoplimab is given as an infusion into a vein over 30 minutes. A healthcare provider will give you this injection.
Narsoplimab is usually given once per week. Your doctor will determine your treatment schedule depending on the condition being treated.
Doses are based on weight. Your dose may change if you gain or lose weight.
Call your doctor if your symptoms do not improve, or if they get worse.
You may get infections more easily, even serious or fatal infections. You will need frequent medical tests.
If you have an infection, you will be watched closely to make sure it does not get worse.
Call your doctor for instructions if you miss an appointment for your narsoplimab injection.
Overdose Signs
What happens if I overdose on Yartemlea (Intravenous)?
In a medical setting an overdose would be treated quickly.