Sevabertinib (Oral)
Sevabertinib is used in adults to treat a certain type of lung cancer called non-small cell lung cancer (NSCLC).
Sevabertinib is used when the cancer has spread within your chest or to other parts of the body (metastatic), or when other cancer treatments did not work or have stopped working.
Your doctor will make sure you have the correct tumor type to be treated with sevabertinib.
Sevabertinib may also be used for purposes not listed in this medication guide.
uses
What is Sevabertinib (Oral) used for?
- Non-Small Cell Lung Cancer
warnings
What is the most important information I should know about Sevabertinib (Oral)?
Tell your doctor if you have or have ever had:
- lung or breathing problems (other than lung cancer); or
- liver disease.
Sevabertinib can harm an unborn baby if the mother or the father is using this medicine.
- If you are a woman, you may need a pregnancy test to make sure you are not pregnant. Use birth control while using this medicine and for at least 1 week after your last dose.
- If you are a man, use birth control if your sex partner is able to get pregnant. Keep using birth control for at least 1 week after your last dose.
Tell your healthcare provider right away if you become pregnant or think you may be pregnant during your treatment with sevabertinib.
Do not breastfeed while using this medicine, and for at least 1 week after your last dose.
Side Effects
What are the side effects of Sevabertinib (Oral)?
Get emergency medical help if you have signs of an allergic reaction: hives, difficult breathing, swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have:
- severe or ongoing diarrhea;
- dehydration--dizziness, confusion, feeling very thirsty, less urination;
- signs of an electrolyte imbalance--increased thirst or urination, constipation, muscle weakness, leg cramps, numbness or tingling, feeling jittery, fluttering in your chest;
- severe vision problems, including vision loss;
- signs of liver or pancreas problems--loss of appetite, upper stomach pain (that may spread to your back), nausea or vomiting, fast heart rate, dark urine, jaundice (yellowing of the skin or eyes); or
- sudden chest pain, wheezing, dry cough, feeling short of breath.
Your cancer treatments may be changed, delayed, or permanently discontinued if you have certain side effects.
Common side effects may include:
- diarrhea, nausea;
- skin rash;
- problems with your nails including infection or inflammation;
- mouth sores; or
- abnormal blood tests.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Pregnancy & Breastfeeding
Can I take Sevabertinib (Oral) if I’m pregnant or breastfeeding?
Do not breastfeed while using this medicine, and for at least 1 week after your last dose.
Interactions
What drugs and food should I avoid while taking Sevabertinib (Oral)?
Grapefruit may interact with sevabertinib and cause side effects. Avoid consuming grapefruit products.
Avoid taking an herbal supplement containing St. John's wort.
Dosage Guidelines & Tips
How to take Sevabertinib (Oral)?
Use Sevabertinib (Oral) exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.
Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.
Your doctor will perform tests to make sure sevabertinib is the right treatment for you.
Sevabertinib is usually taken twice per day with food. Follow your doctor's instructions.
Swallow the tablet whole with a glass of water and do not crush, chew, or break it.
Drink plenty of liquids while you are taking sevabertinib.
If you vomit shortly after taking sevabertinib, do not take another dose. Take your next dose as scheduled.
You may need frequent medical tests including blood tests to check your liver and pancreas function before and during treatment with sevabertinib.
Do not change your dose or stop taking sevabertinib unless your healthcare provider tells you to.
You may be given other medications to help prevent serious side effects or allergic reaction. Keep taking these medicines for as long as your doctor has prescribed.
Store at room temperature away from moisture and heat.
Take the medicine as soon as you remember, and then go back to your regular schedule. Do not take two doses at one time.
Overdose Signs
What happens if I overdose on Sevabertinib (Oral)?
Images
SE, 10
Color: brown/red
Shape: round
Form: film coated
Imprint: SE, 10