Lunsumio Velo (Subcutaneous)
Lunsumio Velo (Subcutaneous)
Mosunetuzumab is used to treat follicular lymphoma (a cancer of the lymphatic system) in adults whose cancer has returned or did not respond to another treatment and who have received at least two previous cancer treatments.
Mosunetuzumab may also be used for purposes not listed in this medication guide.
warnings
What is the most important information I should know about Lunsumio Velo (Subcutaneous)?
Tell your doctor if you have or have ever had:
- an infusion reaction after receiving mosunetuzumab;
- an infection or an infection that lasts a long time or keeps returning; or
- Epstein-Barr Virus (mononucleosis).
May harm an unborn baby. You may need a pregnancy test before starting this treatment. Use effective birth control while using mosunetuzumab and for at least 3 months after your last dose. Tell your doctor if you become pregnant.
Do not breastfeed while using this medicine, and for at least 3 months after your last dose.
Side Effects
What are the side effects of Lunsumio Velo (Subcutaneous)?
Get emergency medical help if you have signs of an allergic reaction: hives, difficult breathing, swelling of your face, lips, tongue, or throat.
Tell your medical caregivers if you have signs of cytokine release syndrome (CRS), a serious side effect: fever, chills, trouble breathing, confusion, severe vomiting or diarrhea, fast or irregular heartbeats, feeling light-headed or very tired.
Call your doctor at once if you have:
- signs and symptoms of nervous system disorders--headache; numbness or tingling in arms, legs, hands, or feet; dizziness, confusion, or disorientation; problems with balance, coordination, or muscle movement; sleepiness or sleeping problems; amnesia or forgetfulness; trouble speaking, writing, or reading; or seizures;
- low blood cell counts--mouth sores, skin sores, easy bruising, unusual bleeding, pale skin, cold hands and feet, feeling light-headed;
- liver problems--loss of appetite, nausea, vomiting, stomach pain (upper right side), itching, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);
- signs or symptoms of tumor related problems--chest pain, cough, breathing problems, tender or swollen lymph nodes, pain or swelling at tumor site; or
- signs of infection--fever, chills, sore throat, body aches, unusual tiredness.
Your cancer treatments may be delayed or permanently discontinued if you have certain side effects.
Common side effects may include:
- pain, bruising, swelling, or irritation where the medicine was injected;
- abnormal lab results;
- diarrhea;
- COVID-19 Infection;
- fever, tiredness;
- rash, itching;
- headache, muscle and joint pain;
- cough; or
- numbness, tingling, or pain in your hands or feet.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Pregnancy & Breastfeeding
Can I take Lunsumio Velo (Subcutaneous) if I’m pregnant or breastfeeding?
May harm an unborn baby. You may need a pregnancy test before starting this treatment. Use effective birth control while using mosunetuzumab and for at least 3 months after your last dose. Tell your doctor if you become pregnant.
Do not breastfeed while using this medicine, and for at least 3 months after your last dose.
Interactions
What drugs and food should I avoid while taking Lunsumio Velo (Subcutaneous)?
Avoid driving or hazardous activity until you know how this medicine will affect you. Your reactions could be impaired.
Dosage Guidelines & Tips
How to take Lunsumio Velo (Subcutaneous)?
Use Lunsumio Velo (Subcutaneous) exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.
Follow all directions on your prescription label and read all medication guides or instruction sheets.
A healthcare provider will give you this medicine. Your doctor will decide how many treatment cycles you will receive of this medicine.
You may be given other medications to help reduce your risk of cytokine release syndrome (CRS). Keep taking these medicines for as long as your doctor has prescribed.
Your healthcare provider will check for CRS while you are being treated with mosunetuzumab and may treat you in a hospital if you develop signs and symptoms of CRS.
You will need frequent medical tests and your cancer treatments may be delayed or discontinued based on the results.
Call your doctor for instructions if you miss an appointment to receive mosunetuzumab.
Overdose Signs
What happens if I overdose on Lunsumio Velo (Subcutaneous)?
In a medical setting an overdose would be treated quickly.