Decnupaz (Intravenous)
Pivekimab sunirine is used in adults to treat a type of blood cancer called blastic plasmacytoid dendritic cell neoplasm (BPDCN).
Pivekimab sunirine may also be used for purposes not listed in this medication guide.
warnings
What is the most important information I should know about Decnupaz (Intravenous)?
Tell your doctor if you have or have ever had:
- asthma or sulfite allergy; or
- liver or kidney disease.
Pivekimab sunirine can harm an unborn baby if the mother or the father is using this medicine.
- If you are a woman, you may need a pregnancy test to make sure you are not pregnant. Use birth control while using this medicine and for at least 7 months after your last dose.
- If you are a man, use birth control if your sex partner is able to get pregnant. Keep using birth control for at least 4 months after your last dose.
- Tell your doctor if you become pregnant or think you may be pregnant.
Do not breastfeed while using this medicine, and for at least 1 month after your last dose.
Side Effects
What are the side effects of Decnupaz (Intravenous)?
Get emergency medical help if you have signs of an allergic reaction: hives, itching, rash, chest pain, difficulty breathing, trouble swallowing, or swelling of your face, lips, tongue, or throat.
Some side effects may occur during the injection. Tell your medical caregiver if you feel dizzy, nauseated, light-headed, itchy, sweaty, or have a headache, chest tightness, back pain, trouble breathing, or swelling in your face.
Call your doctor at once if you have:
- fluid retention--shortness of breath (even while lying down), swelling, rapid weight gain (especially in your face and midsection); or
- liver problems--loss of appetite, nausea, vomiting, stomach pain (upper right side), tiredness, itching, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).
Your treatments may be delayed or permanently discontinued if you have certain side effects.
Common side effects may include:
- a reaction during the injection;
- swelling;
- feeling tired;
- muscle, bone, or joint pain;
- nausea, diarrhea;
- a bleeding that will not stop; or
- abnormal blood tests.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Pregnancy & Breastfeeding
Can I take Decnupaz (Intravenous) if I’m pregnant or breastfeeding?
Do not breastfeed while using this medicine, and for at least 1 month after your last dose.
Interactions
What drugs and food should I avoid while taking Decnupaz (Intravenous)?
Follow your doctor's instructions about any restrictions on food, beverages, or activity.
Dosage Guidelines & Tips
How to take Decnupaz (Intravenous)?
Use Decnupaz (Intravenous) exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.
Pivekimab sunirine is given once every 3 weeks as an infusion into a vein over 15 to 30 minutes. A healthcare provider will give you this injection and will determine the number of treatments you will receive.
Doses are based on weight. Your dose may change if you gain or lose weight.
You may be given other medicines the day before and on the day of your infusion to help prevent certain serious side effects. Keep taking these medicines for as long as your doctor has prescribed.
You will need frequent blood tests to check your liver function. Your treatment may be delayed, reduced, or permanently discontinued based on the results.
Call your doctor for instructions if you miss an appointment for your pivekimab sunirine injection.
Overdose Signs
What happens if I overdose on Decnupaz (Intravenous)?
In a medical setting an overdose would be treated quickly.