Saffron: Nutrition, Benefits, Side Effects, and More

Saffron 101: A Complete Guide

Saffron 101: A Complete Guide
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Note: The U.S. Food and Drug Administration (FDA) does not approve supplements for safety or effectiveness. Talk to a healthcare professional about whether a supplement is the right fit for your individual health, and about any potential drug interactions or safety concerns.

Rare and brilliantly reddish-orange, saffron is made from the threadlike female parts (stigma and style) of the saffron crocus plant (Crocus sativus). It takes 75,000 flowers to produce 1 pound of saffron, making it one of the world’s most expensive spices.

Fortunately, you don’t need much saffron to add warm, earthy, floral flavor to a wide variety of dishes. Many recipes call for a few threads of the whole spice or small amounts (such as 1 teaspoon or less) of the ground version.

Types of Saffron

You’ll find several types of saffron for sale in grocery stores and by specialty cooking suppliers. Some varieties include:

  • Bunch Saffron This type is sold as it’s harvested — in bunches, with roots attached.
  • Pushal Saffron Pushal is a two-toned variety, with red threads attached to golden yellow styles. It’s known for adding a subtle flavor to many Persian dishes.
  • Sargol Saffron Sargol, meaning top of the flower, comes in short threads that include only the red tips of the plant’s stigma.
  • Negin Saffron This type is known for its deep red color and long, thick strands. It’s often used by chefs to create high-end cuisine.
  • Coupe (Spanish) Saffron Coupe’s red stigma tips are used in traditional Spanish dishes.
  • Ground Saffron A powdered version of the spice, ground saffron is a lower-cost alternative.

Saffron Nutrition Facts

According to the U.S. Department of Agriculture (USDA), these are the nutrition facts for 1 teaspoon (tsp) of saffron, which is equal to 0.7 grams (g).

Nutrient
Amount
Daily Value (DV)
Calories
2
Total Fat
0.04 g
0%
Saturated Fat
0 g
0%
Trans Fat
0 g
0%
Cholesterol
0 mg
0%
Sodium
1 mg
0.04%
Total Carbohydrate
0.46 g
0.17%
Dietary Fiber
0 g
0%
Total Sugars
0 g
0%
Added Sugars
0 g
0%
Protein
0.08 g
0.16%
Vitamin D
0 IU
0%
Vitamin C
0.6 mg
0.67%
Calcium
0.78 mg
0.06%
Iron
0.08 mg
0.44%
Potassium
12 mg
0.26%

Potential Health Benefits of Saffron

Saffron has been used in traditional systems of medicine as an aphrodisiac, a contraceptive, a nerve sedative, an appetite stimulant, and a menstrual cycle regulator.

 But research on its potential effectiveness as a dietary supplement is limited. Here are some of the health conditions that saffron may help or prevent.
  • May Boost Mood Some research suggests that the antioxidant compounds found in saffron, including flavonoids, might help relieve symptoms of depression and anxiety by protecting brain cells from inflammation and oxidative stress, and that the compunds influence neurotransmitters such as serotonin and dopamine (hormones critical to mood regulation).

     In a randomized clinical trial of 56 healthy adults who received either saffron extract or a placebo for eight weeks, the authors found that saffron may help relieve stress, yet more research in larger groups is needed.

  • May Improve Sexual Function Just as was suspected in ancient times, one review of five studies published in Iran found that ingesting the spice improved sexual function in both men and women. The review authors weren’t able to draw conclusions about dosage.

  • May Lower Cardiovascular Disease Risk An analysis of 32 studies found that consumption of saffron may decrease cardiovascular disease risk factors like triglycerides, total cholesterol, LDL cholesterol, and systolic blood pressure.

  • May Improve Diabetes Symptoms Some potentially promising research shows that supplementing with saffron may help with glycemic control in those with type 2 diabetes. One larger Iranian study of 562 people with diabetes found those who took between 5 milligrams (mg) and 1 g of saffron for 8 to 12 weeks significantly reduced their fasting blood sugar and A1C levels.

  • May Prevent Eye Diseases Saffron has been studied for its effects on several ocular diseases, with potential benefits for age-related macular degeneration, diabetic retinopathy, retinitis pigmentosa, and glaucoma. Still, more well-designed, larger human studies are needed.

While researchers are investigating the potential benefits for people with schizophrenia and cancer, current evidence is inconclusive. According to the authors of one review, animal studies indicate that crocin (the compound that gives saffron its color) could improve schizophrenia symptoms like social isolation and memory deficit, and one small human trial in Iran found that saffron extract was safe and well tolerated in people with schizophrenia.

Separately, a review of laboratory studies shows that saffron may kill certain cancer cells (such as those of the nervous system) and possibly reduce the toxicity of anti-cancer drugs.

“However, these are early studies from cell and animal research,” says Vandana Sheth, RDN, CDCES, author of My Indian Table: Quick & Tasty Vegetarian Dishes, who is based in Los Angeles. More rigorous, large-scale human research on possible benefits for schizophrenia and cancer is needed, and people with either condition should consult their healthcare provider for established treatment.

Can Saffron Help With Weight Loss?

Saffron has long been touted as a natural weight loss aid. Some older research indicates that supplementing with saffron may reduce snacking and boost feelings of fullness.

On the other hand, a more recent review found that only 3 of 12 studies on saffron for weight loss found that it might improve body mass index, body weight, or waist circumference compared with placebo.

Sheth confirms that there is not enough current research to show that a saffron-enhanced diet will lead to shedding pounds. “The research is still limited and early,” she says. “Saffron may play a supportive role, but is not a standalone weight loss aid.”

How to Select and Store Saffron

Despite the high price tag on some products, purchasing saffron for aromatic cooking doesn’t need to feel intimidating. Here’s how to select and store this unique spice.

Selection

Selecting authentic, high-quality saffron is largely a matter of observing its color. “High-quality saffron has deep red-colored threads with orange tips,” says Sheth. The grade and origin matter, too. “Look for saffron labeled ‘coupe’ or ‘grade 1,’ ideally from Iran, Spain, or Kashmir.”

Sheth also recommends using your senses to guide your purchase. “Choose saffron strands that have a strong and slightly earthy fragrance,” she says.

If you’re concerned about authenticity or purity, you can try a simple at-home test. “Steep a few strands in warm water or milk,” Sheth suggests. “Real, high-quality saffron releases its golden color slowly and evenly while the threads keep their shape. Fake or dyed saffron turns the liquid bright red right away and the threads may also look uneven.”

On the other hand, you also have the option to take saffron as a supplement. When shopping for a supplement, look for those that say USP, NSF, or ConsumerLabs. This means the product has undergone third-party testing for quality and purity.

Storage

Saffron won’t do well when exposed to the elements. “It's best stored in a cool, dark space in an airtight container to help protect its potency and delicate flavor,” Sheth says.

How to Eat Saffron

A little bit of saffron can unlock a lot of culinary adventure. In many recipes, a pinch is all you need. For an idea of what a pinch is, keep in mind that 1 tsp of saffron threads equals about ⅛ tsp of ground saffron.

“Saffron adds a beautiful color and aroma that can be used in both savory and sweet dishes,” Sheth says. “Use it in dishes like paella, risotto, saffron milk, and warm Indian desserts.” To release the full flavor of saffron threads, she recommends soaking the strands in warm water or milk before adding it to your recipe.

Health Risks of Saffron

Saffron is considered safe for human consumption when used in the amount commonly found in recipes.

In larger amounts, saffron could cause organ damage or harm babies in utero, per research out of India. And some research indicates that saffron shouldn’t be used during pregnancy, since it can cause uterine contractions.

Keep in mind, too, that cautions about saffron (Crocus sativus) are easily confused with strong warnings about meadow saffron (Colchicum autumnale), an unrelated plant that is poisonous when eaten.

The Takeaway

  • Saffron is a rare, expensive spice made from the saffron crocus. It’s not nutrient dense, but does add flavor to a variety of dishes and has antioxidant properties that possibly offer health benefits.
  • Early, limited research suggests that saffron may support mental health, improve sexual function, lower heart and eye disease risk, and regulate blood sugar levels.
  • Add saffron for an earthy, savory-sweet boost to dishes like paella, risotto, curry, and even desserts. It’s better to buy whole threads for the highest-quality product.
  • Use caution and speak with your doctor if you are pregnant and interested in eating saffron. High doses of saffron may cause organ damage or harm fetuses.
EDITORIAL SOURCES
Everyday Health follows strict sourcing guidelines to ensure the accuracy of its content, outlined in our editorial policy. We use only trustworthy sources, including peer-reviewed studies, board-certified medical experts, patients with lived experience, and information from top institutions.
Resources
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  5. Midaoui AE et al. Saffron (Crocus sativus L.): A Source of Nutrients for Health and for the Treatment of Neuropsychiatric and Age-Related Diseases. Nutrients. January 2022.
  6. Jackson PA et al. Effects of Saffron Extract Supplementation on Mood, Well-Being, and Response to a Psychosocial Stressor in Healthy Adults: A Randomized, Double-Blind, Parallel Group, Clinical Trial. Frontiers in Nutrition. February 1, 2021.
  7. Ranjbar H et al. Effects of Saffron (Crocus sativus) On Sexual Dysfunction Among Men and Women: A Systematic Review and Meta-Analysis. Avicenna Journal of Phytomedicine. September-October 2019.
  8. Zamani M et al. The Effects of Saffron Supplementation on Cardiovascular Risk Factors in Adults: A Systematic Review and Dose-Response Meta-Analysis. Frontiers in Nutrition. December 2022.
  9. Mousavi B et al. Safety evaluation of saffron stigma (Crocus sativus L.) aqueous extract and crocin in patients with schizophrenia. Avicenna Journal of Phytomedicine. September-October 2015.
  10. Shakeri M et al. Toxicity of Saffron Extracts on Cancer and Normal Cells: A Review Article. Asian Pacific Journal of Cancer Prevention. July 2020.
  11. Gout B et al. Satiereal, a Crocus sativus L Extract, Reduces Snacking and Increases Satiety in a Randomized Placebo-Controlled Study of Mildly Overweight, Healthy Women. Nutrition Research. May 2010.
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Justin Laube

Justin Laube, MD

Medical Reviewer

Justin Laube, MD, is a board-certified integrative and internal medicine physician, a teacher, and a consultant with extensive expertise in integrative health, medical education, and trauma healing.

He graduated with a bachelor's in biology from the University of Wisconsin and a medical degree from the University of Minnesota Medical School. During medical school, he completed a graduate certificate in integrative therapies and healing practices through the Earl E. Bakken Center for Spirituality & Healing. He completed his three-year residency training in internal medicine at the University of California in Los Angeles on the primary care track and a two-year fellowship in integrative East-West primary care at the UCLA Health Center for East-West Medicine.

He is currently taking a multiyear personal and professional sabbatical to explore the relationship between childhood trauma, disease, and the processes of healing. He is developing a clinical practice for patients with complex trauma, as well as for others going through significant life transitions. He is working on a book distilling the insights from his sabbatical, teaching, and leading retreats on trauma, integrative health, mindfulness, and well-being for health professionals, students, and the community.

Previously, Dr. Laube was an assistant clinical professor at the UCLA Health Center for East-West Medicine and the David Geffen School of Medicine at UCLA, where he provided primary care and integrative East-West medical consultations. As part of the faculty, he completed a medical education fellowship and received a certificate in innovation in curriculum design and evaluation. He was the fellowship director at the Center for East-West Medicine and led courses for physician fellows, residents, and medical students.

Sarah-Garone-bio

Sarah Garone

Author
Sarah Garone is a licensed nutritionist, registered nutrition and dietetics technician, freelance health and wellness writer, and food blogger in Mesa, Arizona. She has written for The Washington Post, Healthline, Greatist, Verywell, and Eat This, Not That, among other outlets. She is a member of the Academy of Nutrition and Dietetics.