Libido Supplements: What Are They and Do They Work?

Libido Supplements: What Are They and Do They Work?

Libido Supplements: What Are They and Do They Work?
Adobe Stock; Everyday Health

Note: The U.S. Food and Drug Administration (FDA) does not approve supplements for safety or effectiveness. Talk to a healthcare professional about whether a supplement is the right fit for your individual health, and about any potential drug interactions or safety concerns.

If you’re experiencing sexual dysfunction, such as a sluggish libido or difficulty getting an erection or having an orgasm, you may be tempted to try a supplement. However, it’s important to know that they can have limitations.

Some supplements and herbs claim to deliver instant arousal, orgasms, or erections, but there’s little to no evidence that they actually have such powerful effects.

“There’s not one libido supplement I recommend for that purpose,” says Ellen Barnard, an ASSECT-certified sex educator at A Woman’s Touch Sexuality Resource Center in Madison, Wisconsin. Still, supplements that support overall health, when taken over time, might also improve your sex life, Barnard adds, much in the same way that exercise or a healthy diet can.

Many herbs are marketed as sex enhancers, but the evidence behind these claims is extremely thin, says Ikhlas Khan, PhD, the director of the National Center for Natural Products Research at the University of Mississippi. That doesn’t mean you shouldn’t try a supplement to potentially help your sex life, but “you should be educated as much as you can before you do,” Dr. Khan says. In addition, you should always talk to your healthcare provider, be it about supplementation or to address any underlying causes of sexual dysfunction.

Most studies on libido-boosting supplements are small and not well designed. That means that even the existing evidence should be viewed with caution, and more high-quality research is needed to better understand the effects of these products.

If you take other medications, be aware that some supplements can interfere with prescription drugs. Also, women who are pregnant or nursing should speak with their healthcare provider before taking supplements.

What Are Libido Supplements?

First things first, “low libido” is a drop in sexual desire or interest compared with your usual baseline. It can be temporary or longer-lasting, and it is a common experience for many people.

Many herbs are marketed as sex enhancers, but the evidence behind these claims is extremely thin, says Khan. He coauthored a narrative review of supplements marketed for women’s sexuality published in the Journal of Ethnopharmacology. The paper concluded that there are no high-quality studies proving their effectiveness for women’s libido. “There are so many more questions than answers,” Khan says.

Popular sexual performance supplements often contain a blend of ingredients. Some of the bestselling ones include:

  • Dehydroepiandrosterone (DHEA)
  • Fenugreek
  • Ginkgo biloba
  • Ginseng
  • Horny goat weed
  • L-arginine
  • Maca
  • Tribulus
  • Yohimbe
  • Zinc

Types of Libido Supplements and the Science Behind Them

Walk into any pharmacy or health food store, and you’ll find plenty of supplement products promising to heat up your sex life. Most of these supplements have side effects, and many lack complete ingredient information on the packaging, such as how much of a particular herb or substance is in one capsule, gummy, or tincture. They also often fail to include where the herb or substance has been sourced from. This makes it even harder to evaluate them for quality and purity.

Among the many products claiming to correct sexual dysfunction, here are some of the most popular ones — and some of their purported benefits. However, keep in mind that research in this area is lacking and limited, and it’s best to discuss your concerns with your doctor first.

L-Arginine

Arginine is naturally produced by the body as a semi-essential amino acid. According to the Mayo Clinic, some people take L-arginine for erectile dysfunction because it functions like vasodilator, dilating and relaxing blood vessels.

Doses of 2.5 to 5 grams of L-arginine by mouth daily may “possibly” improve sexual function in people with ED. The supplement might work best when taken along with a proven medication such as Viagra, where it may enhance the effects. However, be sure to speak with your doctor before starting any new supplement, as it may interact with certain medications.

But if you prefer to get your nutrients from whole foods rather than supplements, watermelon contains an amino acid that the body naturally converts to arginine. One past study found that arginine levels rose by 22 percent when watermelon was consumed daily.

However, this study “had a small sample size and focused on postmenopausal women, which limits generalizability,” says Angela Downey, MD, a family physician in private practice in Winnipeg, Manitoba.

Overall, “the research is promising in some areas but generally sparse,” she adds. “Many studies are small, short-term, or not done on women. There’s a big need for more diverse, high-quality trials before we can confidently say what works.”

Possible risks and side effects of L-arginine include:

  • Gastrointestinal upset (stomach pain, bloating, diarrhea)
  • Gout
  • Headache
  • Allergic response
  • Airway inflammation or worsening of asthma symptoms
People who have had a heart attack or kidney disease shouldn’t take this supplement. Pregnant or lactating women, and anyone who is planning to have surgery, should speak with a healthcare provider about what their possible risks are.

Yohimbe

This herb comes from an evergreen tree native to parts of Africa. A compound in the bark, called yohimbine, has traditionally been used to enhance sexuality in men, Khan says. According to one review, yohimbe appears to have some benefit on male erectile function when combined with L-arginine or ginseng.

 No evidence exists to determine whether it benefits female sexual function.

However, “this study is a broad scientific review, not a clinical trial, so it’s more about mechanisms than real-world outcomes,” says Dr. Downey. “Also, lots of the research it cites is animal-based or outdated.”

A number of serious risks have been associated with yohimbe, including:

  • Heart attacks
  • Seizures
  • Anxiety
  • Stomach problems
  • Rapid heart rate
  • Increased blood pressure

Be sure to speak with your healthcare provider before starting a yohimbe supplement, to make sure you are not at risk of any of these conditions or concerns, says Downey.

Ginkgo Biloba

Ginkgo biloba, sometimes referred to simply as ginkgo, is one of the oldest living tree species in the world, and its leaves and seeds have long been used in traditional Chinese medicine. Its efficacy has been studied for the treatment of conditions that include heart and lung dysfunction, and skin infections.

One past review from India noted that it’s promoted as a way to potentially help with premature ejaculation.

Another previous study suggested that it may also help ease decreased libido in women.

One systematic review of five randomized controlled trials out of Iran found that the herb may have positive effects on sexual function in postmenopausal women, possibly by increasing blood flow to the genitals, but there is no evidence it helps anyone else.

In another systematic review, researchers found no consistent benefit of ginkgo biloba in three randomized controlled trials, compared with a placebo.

That said, “these recent studies are mostly preclinical or theoretical,” says Downey. “Some small human trials suggest benefits, but results are mixed. Doses, durations, and populations studied differ a lot.”

Ginkgo leaf extracts are relatively safe when taken in moderate amounts.

 Most studies on the herb use 120 to 240 milligrams, taken daily in divided doses.

Still, there are potential side effects when taking ginkgo, including:

  • Headache
  • Dizziness
  • Upset stomach and constipation
  • Heart palpitations
  • Bleeding in those with a known bleeding risk

Downey also notes that ginkgo can interact with medications like blood thinners, so it’s important to talk to your doctor before you try this supplement to make sure it’s safe for you.

Ginseng

The root of the ginseng plant has been used for thousands of years and may help boost energy levels.

Khan’s aforementioned narrative review cites some positive results from several small studies evaluating the herb’s effects on the fatigue and sexuality of women in menopause. For example, in one randomized controlled trial conducted in Iran, 62 women received either 500 milligrams of ginseng or a placebo, and after a month, those taking ginseng reported enhanced sexual function and fewer bothersome menopausal symptoms.

However, in another systematic review, researchers looked at 15 randomized-controlled trials and included a meta-analysis of three separate studies, which found that ginseng didn’t produce a positive effect on women’s sexual function. Notably, the review flagged risks of bias such as incomplete outcome data and a significant number of dropouts, raising questions about the reliability of the findings.

While research is limited and unclear about the potential benefits of ginseng for sexual dysfunction, taking the herb does come with possible risks and side effects including:

  • Insomnia
  • Skin rash, irritation, or burning
  • Liver damage
  • Low blood sugar
  • Allergic reaction

Kava

Kava is a plant native to the South Pacific. In several Pacific Island cultures, including those in Micronesia, Polynesia, and Melanesia, kava root has been prepared as a medicinal drink to relieve pain, promote relaxation, and ease insomnia.

Similarly, kava is used in herbal supplement form to ease symptoms of anxiety.

It has also been associated with better sex, possibly due to its potential effect on anxiety. In one small, past study, when researchers gave kava supplements or a placebo to people with generalized anxiety disorder, they found that women who took it had increased sex drive. They also observed that people whose anxiety decreased also reported the greatest improvement in sexual function and performance.

On the other hand, kava has been associated with rare and sometimes fatal liver damage. These incidents have been linked to kava products made with water, acetone, or alcohol, or from consuming certain varieties of the kava plant, the incorrect plant parts, or mixing it with alcohol. Contamination or genetic variables may also play a role.

Other side effects of kava include:

  • Headache
  • Dizziness
  • Digestive upset
  • Headache
  • Dry, flaky skin

Fenugreek

This clover-like herb is native to parts of Europe and Asia.

Its phytoestrogen-rich seeds, which have similar benefits as estrogen, are used as an ingredient in spice blends. (The seeds’ extract is also available in capsules and powders.)

One small past study of 80 women ages 20 to 49 found increased sexual desire and arousal in participants who took 600 milligrams of fenugreek per day over two menstrual cycles, compared with a control group who received a placebo.

But a systematic review conducted in Iran showed mixed results with fenugreek in menopausal women who experienced sexual dysfunction. As Khan’s narrative review notes, much more evidence is needed before fenugreek can be considered an effective aphrodisiac.

Overall, the evidence is mixed, highlighting the need for larger and more diverse clinical studies, Downey notes.

Side effects of fenugreek include:

  • Diarrhea and nausea
  • Headache
  • Dizziness
  • Drop in blood sugar (when taken in large doses)
  • Allergic reactions, such as hives anywhere on the body, or a tingling or itchy feeling in the mouth

Who May Want to Try Libido Supplements

Libido supplements may appeal to adults experiencing mild, occasional dips in sex drive, especially when those changes are linked to factors like stress or hormonal shifts (such as menopause or perimenopause), says Downey.

To choose a quality supplement, check the label for approvals from USP, NSF, or ConsumerLab. These indicate that the product has undergone third-party testing for quality and purity.

That said, supplements touting possible benefits for sexual dysfunction are not recommended for everyone. Women who are pregnant or breastfeeding should avoid libido supplements unless approved by a doctor, as there’s little research to show how they may affect a developing fetus. The same goes for people taking prescription medications or managing chronic health conditions, as many supplements contain herbs or compounds that can interact with certain drugs, such as blood thinners.

It’s also worth noting that low libido or sexual dysfunction can be a sign of an underlying health condition, such as cardiovascular disease, diabetes, a urinary tract infection, depression, anxiety, or hormonal changes.

For that reason, it’s best to consider supplements as a potential complement to — not a replacement for — medical care, and to check with your doctor before incorporating any of them into your routine.

The Takeaway

  • Many libido supplements are marketed with bold claims.
  • Herbs like ginseng, fenugreek, L-arginine, and ginkgo biloba may offer some support for sexual function in some people, but studies on their effects are mixed and limited.
  • Many ingredients in libido supplements may interact with common medications.
  • It is vital to know the root cause of your sexual dysfunction before starting supplements.
  • Speak with a healthcare provider before starting supplements, and check in again if your circumstances change while taking them.

Additional reporting by Meryl Davids Landau.

EDITORIAL SOURCES
Everyday Health follows strict sourcing guidelines to ensure the accuracy of its content, outlined in our editorial policy. We use only trustworthy sources, including peer-reviewed studies, board-certified medical experts, patients with lived experience, and information from top institutions.
Resources
  1. Can Supplements Save Your Sex Life? Harvard Health Publishing. May 11, 2021.
  2. Low Libido (Low Sex Drive). Cleveland Clinic. April 21, 2025.
  3. Prescott H et al. Medicinal Plants/Herbal Supplements as Female Aphrodisiacs: Does Any Evidence Exist to Support Their Inclusion or Potential in The Treatment of FSD? Journal of Ethnopharmacology. April 6, 2020.
  4. Cui T et al. A Urologist’s Guide to Ingredients Found in Top-Selling Nutraceuticals for Men’s Sexual Health. Journal of Sexual Medicine. 2015.
  5. L-Arginine. Mayo Clinic. June 28, 2025.
  6. L-Arginine. MedlinePlus. February 2, 2025.
  7. Collins JK et al. Watermelon Consumption Increases Plasma Arginine Concentrations in Adults. Nutrition. March 2007.
  8. L-Arginine: Does It Lower Blood Pressure? Mayo Clinic. June 13, 2024.
  9. Nowacka A et al. Multifaceted Nature of Yohimbine — a Promising Therapeutic Potential or a Risk? International Journal of Molecular Sciences. November 29, 2024.
  10. Yohimbe. National Center for Complementary and Integrative Health. May 2025.
  11. Akaberi M et al. Ginkgo biloba: An updated review on pharmacological, ethnobotanical, and phytochemical studies. Pharmacological Research – Modern Chinese Medicine. December 2023.
  12. Gajjala SR et al. Premature Ejaculation: A Review. Indian Journal of Sexually Transmitted Diseases and AIDS. July 2014.
  13. Meston CM et al. Short- and Long-Term Effects of Ginkgo Biloba Extract on Sexual Dysfunction in Women. Archives of Sexual Behavior. February 15, 2008.
  14. Mashhadi ZN et al. A systematic review of clinical trials on Ginkgo (Ginkgo biloba) effectiveness on sexual function and its safety. Avicenna Journal of Phytomedicine. July 2021.
  15. Concerto C et al. A Systematic Review on the Effect of Nutraceuticals on Antidepressant-Induced Sexual Dysfunctions: From Basic Principles to Clinical Applications. Current Issues in Molecular Biology. July 25, 2022.
  16. Ginkgo. National Center for Complementary and Integrative Health. February 2025.
  17. Ginkgo. LiverTox. March 14, 2018.
  18. Li X et al. Ginseng and Ginseng Herbal Formulas for Symptomatic Management of Fatigue: A Systematic Review and Meta-Analysis. Journal of Integrative and Complementary Medicine. August 9, 2023.
  19. Ghorbani Z et al. The effect of ginseng on sexual dysfunction in menopausal women: a double-blind, randomized, controlled trial. Complementary Therapies in Medicine. August 2019.
  20. Lee HW et al. Using Ginseng for Menopausal Women’s Health Care: A Systematic Review of Randomized Placebo-Controlled Trials. Complementary Therapies in Clinical Practice. August 2022.
  21. Asian Ginseng. National Center for Complementary and Integrative Health. February 2025.
  22. Bian T et al. Kava as a Clinical Nutrient: Promises and Challenges. Nutrients. October 5, 2020.
  23. Kava. National Center for Complementary and Integrative Health. April 2025.
  24. Sarris J et al. Kava for the Treatment of Generalized Anxiety Disorder RCT: Analysis of Adverse Reactions, Liver Function, Addiction, and Sexual Effects. Phytotherapy Research. January 24, 2013.
  25. Fenugreek. National Center for Complementary and Integrative Health. February 2025.
  26. Thomas JV et al. Phytoestrogenic effect of fenugreek seed extract helps in ameliorating the leg pain and vasomotor symptoms in postmenopausal women: a randomized, double-blinded, placebo-controlled study. PharmaNutrition. December 2020.
  27. Rao A et al. Influence of a Specialized Trigonella foenum‐graecum Seed Extract (Libifem), on Testosterone, Estradiol and Sexual Function in Healthy Menstruating Women, a Randomised Placebo Controlled Study. Phytotherapy Research. April 24, 2015.
  28. Koliji T et al. A Systematic Review of Herbal Medicines to Improve the Sexual Function of Menopausal Women. Journal of Herbmed Pharmacology. August 16, 2020.
  29. Herbal Supplements: Why to Check With a Healthcare Provider First. Cleveland Clinic. February 13, 2024.
  30. Complementary and Alternative Medicine. National Cancer Institute. October 31, 2024.
kayli-anderson-bio

Kayli Anderson, RDN

Medical Reviewer

Kayli Anderson has over a decade of experience in nutrition, culinary education, and lifestyle medicine. She believes that eating well should be simple, pleasurable, and sustainable. Anderson has worked with clients from all walks of life, but she currently specializes in nutrition therapy and lifestyle medicine for women. She’s the founder of PlantBasedMavens.com, a hub for women to get evidence-based, practical, and woman-centered guidance on nutrition and cooking, hormone health, fertility, pregnancy, movement, mental well-being, nontoxic living, and more.

Anderson is board-certified in lifestyle medicine and serves as lead faculty of the American College of Lifestyle Medicine’s (ACLM) "Food as Medicine" course. She is past chair of the ACLM's registered dietitian member interest group, secretary of the women's health member interest group, and nutrition faculty for many of ACLM's other course offerings. She is the coauthor of the Plant-Based Nutrition Quick Start Guide and works with many of the leading organizations in nutrition and lifestyle medicine to develop nutrition content, recipes, and educational programs.

Anderson frequently speaks on the topics of women’s health and plant-based nutrition and has coauthored two lifestyle medicine textbooks, including the first one on women’s health, Improving Women's Health Across the Lifespan.

She received a master's degree in nutrition and physical performance and is certified as an exercise physiologist and intuitive eating counselor. She's a student of herbal medicine and women's integrative and functional medicine. She lives with her husband in the Colorado Rocky Mountains, where you’ll find her out on a trail or in her garden.

Diana Rodriguez

Diana Rodriguez

Author

Diana Rodriguez is a Kentucky-based health news writer. She is skilled at turning confusing doctor-speak and complex medical topics into understandable language for readers. She is a managing editor at Mayo Clinic and has written extensively for HealthDay.