What Is Dementia?

Dementia is not a disease. Instead, it is a syndrome — a set of symptoms — that occurs when neurons (nerve cells) in the brain stop working, lose connections with other brain cells, and die.
Dementia ranges from mild to severe. In the final stages, people become completely incapable of caring for themselves and require around-the-clock help with the most basic aspects of daily living.
Up to half of all men and women ages 85 and older (sometimes called “the oldest old”) have some form of dementia, yet experts do not consider it a normal part of aging. Many people live into their nineties with their cognitive abilities intact.
Some people with dementia may be unable to control their emotions, or they may exhibit personality changes.
Dementia is different for everybody. Kalisha Bonds-Johnson, PhD, RN, of Emory University’s Nell Hodgson Woodruff School of Nursing in Atlanta, Georgia, explains how.
Next up video playing in 10 seconds
If You Know One Person With Dementia…
Stages of Dementia
Outlining the stages of dementia, however, can be useful for people considering their future caregiving needs, hoping to enlist in clinical trials, or otherwise planning ahead.
Each of the four most common types of dementia (Alzheimer’s, vascular dementia, Lewy body dementia, and frontotemporal disorders) has early symptoms that can help a doctor identify the type. Unlike the short-term memory loss of Alzheimer’s, for instance, vascular dementia may reveal itself as difficulty making plans or decisions.
- Short-term memory loss
- Loss of awareness of surroundings
- Difficulty communicating
Signs and Symptoms of Dementia
- Memory
- Language skills
- Visual perception
- The ability to focus and pay attention
- The ability to reason and solve problems
An accurate diagnosis is the first step toward getting the right kind of treatment and support for your dementia.
Causes and Risk Factors of Dementia
Dementia occurs when nerve cells in the brain stop working, lose connections with other brain cells, and die. Researchers are still working to understand why this happens and are investigating the role that genetics, lifestyle, and environment all play as dementia risk factors.
Scientists have observed an association between certain kinds of dementia and high levels of proteins in the brain, as with the protein beta-amyloid (plaques) in Alzheimer’s disease.
Lewy body dementia, the third most common form of dementia, is associated with abnormal deposits of a protein called alpha-synuclein. In a healthy brain, alpha-synuclein helps neurons communicate. But when alpha-synuclein begins to clump inside neurons, forming so-called Lewy bodies, brain function is impaired, impacting thinking, movement, behavior, and mood.
Vascular dementia has been linked to damaged arteries that block the flow of blood to areas of the brain, depriving brain cells of the oxygen and nutrients they need to function. Sometimes, small blockages in blood vessels don’t cause any immediate symptoms but can lead to dementia as more and more of the brain becomes damaged.
Risk factors include:
- A buildup of fatty deposits in the arteries, known as atherosclerosis
- High cholesterol
- High blood pressure
- Diabetes
- Smoking
How Is Dementia Diagnosed?
However, the right diagnosis is critical to getting the best treatment. Typically, this process starts with your primary care doctor, although specialists such as a neurologist, neuropsychologist, or geriatrician may also play a role.
The first task is ruling out treatable or reversible conditions with symptoms that can mimic dementia, such as depression or a thyroid problem. Your doctor will take a detailed medical history, conduct a physical exam and a neuropsychological assessment, and order lab tests.
Neuropsychological assessments help doctors identify cognitive patterns that may indicate a particular brain disorder. These tests assess cognitive skills such as memory, problem-solving, language abilities, and focus.
Treatment and Medication Options for Dementia
There is currently no cure for any of the progressive brain diseases that cause dementia. But there are several potential ways to treat dementia, depending on your underlying condition.
Medication Options
Disease-Modifying Monoclonal Antibody Therapies
Examples of disease-modifying monoclonal antibody therapies include:
- lecanemab (Leqembi)
- donanemab (Kisunla)
Cholinesterase Inhibitors
Cholinesterase inhibitors include:
- donepezil (Aricept)
- rivastigmine (Exelon)
- galantamine (Razadyne)
Blood Pressure and Cholesterol Medication
Antidepressants
Behavioral and Occupational Therapy
Hundreds of clinical trials in the United States are looking at dementia. Investigators working with people online and at centers around the country are studying both pharmaceutical and nonpharmaceutical interventions.
Lifestyle Changes for and Prevention of Dementia
Lifestyle Changes for Dementia
Reduce Stress
People with dementia may improve their quality of life by focusing on their overall well-being and taking steps to reduce stress, simplify tasks, and reduce clutter at home.
Eat Well and Exercise
You can enhance your physical health by staying active, eating well, and engaging in activities that involve social interaction or stimulate your brain.
Stay Social and Find Meaning
To boost psychological health, relationships are key. Having close friends who can provide emotional support can lift your feelings of well-being and self-worth.
People with dementia can also nourish their spiritual health by taking part in meaningful activities, whether that means outings with family and friends or quiet, meditative moments alone pursuing a hobby like yoga.
Caregivers can help improve the quality of life for people with dementia by knowing the best ways to communicate and having strategies to overcome cognitive or behavioral challenges. For instance, presenting complex tasks step by step can increase the likelihood of success and foster confidence.
Keep a Routine
Prevention of Dementia
While your genetic makeup is known to play a role in dementia risk, in most cases it’s just one piece of the puzzle. Researchers are actively investigating lifestyle and environmental factors that may increase or decrease your risk of developing dementia.
Keep Your Heart Healthy
Stay Social
Get Better Sleep
How Long Does Dementia Last?
Dementia is an ongoing condition that becomes more severe over time. How quickly your dementia progresses will depend on many factors, including the type of dementia you have, and it varies from person to person.
People with vascular dementia typically live for about five years and are more likely to die from a stroke or heart attack than from their dementia. Those with Lewy body dementia typically live for about six years.
Complications of Dementia
Aspiration Pneumonia and Respiratory Infections
Swallowing difficulties can also contribute to dehydration, malnutrition, and respiratory infections. In advanced dementia, aspiration pneumonia is a leading cause of hospitalization and death, highlighting the importance of monitoring swallowing function and respiratory health.
Malnutrition and Weight Loss
Falls and Functional Decline
Delirium and Neuropsychiatric Complications
Pressure Injuries and Immobility
Increased Mortality
FAQ
- What Is Dementia? Symptoms, Types, and Diagnosis. National Institute on Aging. December 8, 2022.
- Mild Cognitive Impairment (MCI). Alzheimer’s Association.
- Stages of Alzheimer’s. Alzheimer’s Association.
- Vascular Cognitive Impairment and Vascular Dementia. Mayo Clinic. September 18, 2025.
- Lewy Body Dementia: Causes, Symptoms, and Diagnosis. National Institute on Aging. January 27, 2025.
- Frontotemporal Disorders: Causes, Symptoms, and Diagnosis. National Institute on Aging. January 22, 2025.
- Primary Progressive Aphasia. Mayo Clinic. February 7, 2025.
- Who Gets Frontotemporal Dementia? Alzheimer’s Society.
- Frontotemporal Dementia. Mayo Clinic. December 23, 2025.
- Alzheimer’s Disease Facts and Figures. Alzheimer’s Association. 2026.
- Dementia: Diagnosis and Treatment. Mayo Clinic. June 7, 2025.
- Navigating Treatment Options. Alzheimer’s Association. 2026.
- Espay AJ et al. Lecanemab and Donanemab as Therapies for Alzheimer's Disease: An Illustrated Perspective on the Data. eNeuro. June 28, 2024.
- Treatment Options. LewyBodyDementia Association. 2026.
- Vascular Cognitive Impairment and Vascular Dementia. Mayo Clinic. September 28, 2025.
- Why Participate in a Clinical Trial? Alzheimer’s Association. 2026.
- Sommerlad Andrew et al. Social Participation and Risk of Developing Dementia. Nature Aging. May 18, 2023.
- Budson AE. Sleep Well — and Reduce Your Risk of Dementia and Death. Harvard Health Publishing. May 3, 2021.
- The Later Stage of Dementia. Alzheimer’s Society. 2026.
- Dementia. Mayo Clinic. June 7, 2025.
- Dementia and diet. British Dietetic Association. November 5, 2024.
- Delirium and dementia: symptoms, causes and treatment. Dementia UK. June 2025.
- Mental, physical and speech abilities in later stages of dementia. Alzheimer’s Society.
- Pipitone F et al. Soft Tissue Changes in Dementia: A Comprehensive Systematic Review. Aging Brain. 2026.

Angela D. Harper, MD
Medical Reviewer
Angela D. Harper, MD, is in private practice at Columbia Psychiatric Associates in South Carolina, where she provides evaluations, medication management, and psychotherapy for adul...

Pamela Kaufman
Author
Pamela Kaufman assigns and edits stories about infectious diseases and general health topics and strategizes on news coverage. She began her journalism career as a junior editor on...