The Link Between Gallstones, Obesity, and Weight Loss

Obesity and Gallstones
How to Lose Weight Safely to Reduce Your Risk of Gallstones
Gallstones are such a common occurrence after bariatric surgery that patients are routinely given ursodiol, a medication that helps prevent stone formation by decreasing cholesterol production and dissolving it in bile.
Weight loss of ½ to 2 lbs per week is a good goal for most people. Modest weight loss not only helps prevent gallstones, it also encourages new habits that can help put an end to losing and regaining weight repeatedly — and weight cycling is another risk factor for gallstones.
When it comes to gallstone prevention, the type of food you eat doesn’t really matter, says Silverman; the important thing is to avoid eating too much. That being said, extremely low-fat diets are not a great idea because they inhibit gallbladder contractions, making it harder for the gallbladder to empty and allowing bile to accumulate and calcify instead of being released into the small intestine.
Weight loss is best achieved with increased activity and a sustainable diet that doesn’t leave you feeling hungry, fatigued, or deprived. Consider working with a registered dietitian to develop a customized eating plan. And then try some of these weight loss tips that actually work to develop fad-resistant strategies that will help you achieve your goals:
- Plan your meals in advance, especially when eating out. Menus are often posted online, which makes this a lot easier.
- Keep a food journal. People who log everything they consume within 15 minutes of eating lose more weight than those who either don’t keep a journal or wait to record their entries.
- Create a file (online or hard copy) of your favorite low-calorie recipes, and try to always have a stash of key ingredients in your fridge or cupboard.
- Keep healthy, low-calorie snacks in your home, office, car, bag — wherever! This will help you stay on track when the munchies hit and the only thing around is junk food.
- Identify and address “triggers” for unhealthy eating. This may be as simple as moving a candy dish off your coffee table or as challenging as getting to the bottom of why you eat when stressed or bored.
- Eat only until you’re satisfied, not until you’re stuffed. If you eat slowly and mindfully, you’re less likely to overeat because it takes about 15 to 20 minutes for your brain to register that your stomach is full.
- Try not to multitask while eating. Turn off the TV, power down your computer, and don’t take or make calls during meals. Talking to dining companions is perfectly fine, of course — you can’t (or shouldn’t) talk and eat at the same time, so a good conversation can help extend the mealtime and prevent overeating.
- Make sure you get enough sleep. Sleep deprivation sets you up for weight gain by increasing hunger and decreasing your ability to resist comfort foods.
Finally, don’t expect to be perfect. Stuff happens, and you can’t always control what, where, and how you eat. The occasional extra piece of pizza or a couch potato day will not ruin your weight loss efforts or result in a spontaneous gallstone. Just try to learn from the experience so you can prevent it from happening again, and then get right back to your healthy eating and exercise plan.
The Takeaway
- Gallstones form when bile contains too much cholesterol or bilirubin and not enough bile acids, potentially causing significant discomfort.
- Losing weight steadily can lower your risk, while crash diets can lead to gallstone formation.
- Eating mindfully and planning your meals can help you lose weight in a healthy, sustainable way.
- Definition and Facts for Gallstones. National Institute of Diabetes and Digestive and Kidney Diseases. November 2017.
- Gallstones. Cleveland Clinic. January 15, 2024.

Sean Hashmi, MD
Medical Reviewer
Sean Hashmi, MD, is an experienced nephrologist and obesity medicine specialist based in Southern California. As the regional director for clinical nutrition and weight management ...

Erica Ilton, RDN, CDN
Author
Erica Ilton, RDN, CDN, is a registered dietitian nutritionist with a private practice in New York City. She is a Lead Dietitian at FODMAP Everyday, a website devoted to education a...