Why Is Getting Pregnant After 35 More Difficult?

Finding out that you’re not having the fertility journey you expected can be emotionally challenging. However, even if you’re trying to get pregnant after 35, age is just one factor that can affect fertility, and you still have options open to you.
This article aims to help you understand how pregnancy works and learn ways to optimize your chances of getting pregnant by trying other natural and clinical methods.
The Role of Age in Pregnancy, and Fertility Basics
Normal, age-related declines in fertility are most pronounced in women over 35 years of age.
Semen is the substance that comes out of the penis during ejaculation. It contains millions of tiny sperm cells combined with other fluids. Most sperm won’t make it all the way from the vagina through the cervix and uterus and into the fallopian tubes, where fertilization takes place. In fact, only a single sperm will fertilize an egg.
There are two fallopian tubes. Each connects one of a woman’s two ovaries to her uterus. Once a month, one egg will leave one of a woman’s ovaries and travel into one of the fallopian tubes. This is called ovulation.
Age and Aging Are Important Fertility Factors
Pregnancy happens when a man’s sperm fertilizes a woman’s egg. The fertilized egg attaches itself successfully to the wall of the woman’s uterus, where it will continue to grow for the next nine months.
Common Factors That Can Limit Fertility
Both men and women can have fertility problems. While you can’t change your age, there are other steps couples can take to optimize fertility, even in their late thirties. Some causes of infertility can be reversed.
- Being overweight or obese: Overweight and obesity are clearly linked to fertility problems in both men and women. Women who are underweight may also be at risk of infertility. Reaching and maintaining a healthy weight through exercise and healthy eating can help to reverse many fertility problems associated with weight.
- Smoking: Men who smoke are more likely to have sperm that are shaped abnormally or don’t swim properly, or to not have enough sperm. Women who smoke may reach menopause around two years earlier than women who don’t smoke.
- Heavy alcohol consumption or recreational drug use: These behaviors can lead to fertility problems in both men and women. They can also contribute to irregular, heavy, or absent periods, meaning that conceiving can get more difficult as you ovulate less often.
- Steroids: Using anabolic steroids has been linked to infertility in men.
Medical Factors and Underlying Conditions That Can Affect Fertility
Some causes of infertility in women and men are medical. Luckily, many of these problems can be improved with medicine or surgery.
Medical conditions that can decrease a woman’s fertility include:
- Ovulation problems: Most cases of female infertility stem from ovulation issues. Absent or irregular periods could signal issues with ovulation.
- Fallopian tube blockage: An obstruction in one or both fallopian tubes can make it harder for a fertilized egg to get to the uterus.
- Endometriosis: The growth of uterine tissue outside the uterus, or endometriosis, can cause menstrual irregularities or blockages in the fallopian tubes or ovaries that can impact fertility.
- Polycystic ovary syndrome: PCOS or other hormonal conditions can cause ovulation problems.
- Physical problems with the uterus: Uterine fibroids are noncancerous tumors that can develop on the walls of the uterus. While most women with uterine fibroids have no issues with fertility, fibroids can sometimes cause infertility or problems with pregnancy.
- Testicular problems Having an undescended testicle, a gonadal disorder, or an injury to a testicle can cause problems for testicular function and sperm production.
- Hormonal imbalances Hormonal disorders, including low testosterone or thyroid problems, can lead to fertility problems.
- Sperm problems Some men have problems producing enough sperm, may produce sperm that are abnormally shaped, or make sperm that aren’t effective. These sperm may have difficulty reaching and fertilizing the egg.
- Blockages Obstructions in the ducts that carry sperm out of the testicles can result in fertility problems.
- Problems ejaculating For example, performance anxiety around fertility or other reasons might make ejaculating difficult, leading to delayed ejaculation. Also, a condition called retrograde ejaculation may mean sperm ends up in the bladder rather than the penis, often as a side effect of some medications.
- Varicocele This enlargement of veins in the scrotum may harm sperm production and is present in about 30 percent of men with fertility problems, but 10 percent of those without.
How to Naturally Boost Your Chances of Getting Pregnant
Getting pregnant takes time. Even for fully fertile couples in their twenties and early thirties, getting pregnant may routinely take several months. In your late thirties, you may feel you no longer have the luxury of time.
Luckily, you can take a few steps to optimize your natural fertility and conceive as quickly as possible. These include tracking ovulation and timing sex around ovulation.
What Is the Fertility Window?
The best way to get pregnant is to have sex every one to two days during the fertility window.
Not all women have a 28-day cycle. Normal menstrual cycle length varies among women, and some women have cycles that change length from month to month.
Using Fertility Awareness-Based Methods
Fertility awareness-based methods can help couples better understand a woman’s monthly cycle and when she’s ovulating so that they can make the most of the fertile window.
- Keep a menstrual calendar. This can help you become more aware of when you menstruate and ovulate.
- Take your basal body temperature each morning. A woman’s body temperature may fluctuate around 0.5 degrees F around the time of ovulation, so tracking when that change occurs can help to observe your body’s monthly pattern.
- Check your cervical mucus. As a woman gets close to ovulation, her cervical mucus goes from being thick and cloudy to thinner, clearer, and more slippery.
- Use an ovulation predictor kit. These pee-on-a-stick kits detect luteinizing hormone, a hormone that peaks just before ovulation.
Opt for Fertility-Friendly Vaginal Lubrication or Lube
- Cellulose-based lubricants, including Pre-Seed and ConceivEase
- Mineral oil
- Canola oil
Be Open to Fertility Evaluation and Treatment
The Takeaway
- For couples struggling with conception after 35, it's important to know that this age-related fertility decline is common but that there are also viable steps and treatments available.
- Maintaining a healthy lifestyle by regulating weight, avoiding smoking and excessive alcohol, and tracking ovulation can help enhance fertility naturally.
- If you try to get pregnant for six months without success, especially for women over 35, seeing a healthcare professional for a fertility evaluation can help you find out why and improve your odds.
- While advanced age can present challenges, modern medical interventions are helping many achieve successful pregnancies later in life, offering hope for older prospective parents.
Resources We Trust
- Cleveland Clinic: Advanced Maternal Age
- Centers for Disease Control and Prevention: Infertility: Frequently Asked Questions
- American College of Obstetricians and Gynecologists: Thinking About Having a Baby in Your Late 30s or 40s? Here’s What I Tell My Patients
- Johns Hopkins Medicine: Why Can’t I Get Pregnant?
- RESOLVE: The National Infertility Association: Find a Support Group
- Infertility Prevalence Estimates, 1990-2021. World Health Organization. 2023.
- How Pregnancy Happens. Planned Parenthood.
- Advanced Maternal Age. Cleveland Clinic. May 5, 2025.
- Evaluating Infertility. American College of Obstetricians and Gynecologists. November 2024.
- Menopause. Cleveland Clinic. June 24, 2024.
- Can You Get Pregnant During Perimenopause? Yes — Here’s Why. University Hospitals. August 8, 2025.
- What You Need to Know About Pregnancy After Age 40. Mayo Clinic. December 18, 2023.
- Having a Baby After Age 35: How Aging Affects Fertility and Pregnancy. American College of Obstetricians and Gynecologists. April 2025.
- Does My Age Affect My Fertility? American Society for Reproductive Medicine. 2023.
- Gautam D et al. The Challenges of Obesity for Fertility: A FIGO Literature Review. Gynecology & Obstetrics. January 12, 2023.
- Underweight and Fertility When Planning a Pregnancy. Tommy’s. August 29, 2023.
- Sustarsic A et al. The Influence of Lifestyle Interventions and Overweight on Infertility: A Systematic Review, Meta-Analysis, and Meta-Regression of Randomized Controlled Trials. Frontiers in Medicine. November 1, 2023.
- How Smoking Affects Female and Male Fertility. Tommy’s. August 29, 2023.
- Early or Premature Menopause. Office on Women’s Health. March 11, 2025.
- Drugs, Alcohol and Trying to Conceive. Tommy’s. August 29, 2023.
- Ledesma BR et al. Fertility Outcomes in Men With Prior History of Anabolic Steroid Use. Fertility and Sterility. December 2023.
- Infertility: Frequently Asked Questions. Centers for Disease Control and Prevention. May 15, 2024.
- What Are Some Possible Causes of Female Infertility? National Institute of Child Health and Human Development. January 31, 2017.
- Understanding Fertility: The Basics. Office of Population Affairs.
- What Are Some Possible Causes of Male Infertility? National Institute of Child Health and Human Development. January 31, 2017.
- Ducharme S et al. Ejaculation Problems: Too Fast, Too Slow or Not at All? Center for Sexual Medicine at Boston University School of Medicine.
- Nonsurgical Treatment for Male Infertility Caused by Varicoceles. University of California, San Francisco.
- Calculating Your Monthly Fertility Window. Johns Hopkins Medicine.
- Fertility Awareness-Based Methods of Family Planning. American College of Obstetricians and Gynecologists. February 2025.
- Trying to Get Pregnant? Select a Lubricant Most Helpful for Sperm. Mayo Clinic Health System. November 17, 2022.
- Practice Committee of the American Society for Reproductive Medicine in collaboration with the Society for Reproductive Endocrinology and Infertility. Optimizing Natural Fertility: A Committee Opinion. Fertility and Sterility. January 2017.
- Harris BS et al. Markers of Ovarian Reserve as Predictors of Future Fertility. Fertility and Sterility. November 29, 2022.

Kara Smythe, MD
Medical Reviewer
Kara Smythe, MD, has been working in sexual and reproductive health for over 10 years. Dr. Smythe is a board-certified fellow of the American College of Obstetricians and Gynecologists, and her interests include improving maternal health, ensuring access to contraception, and promoting sexual health.
She graduated magna cum laude from Florida International University with a bachelor's degree in biology and earned her medical degree from St. George’s University in Grenada. She completed her residency in obstetrics and gynecology at the SUNY Downstate Medical Center in Brooklyn, New York. She worked in Maine for six years, where she had the privilege of caring for an underserved population.
Smythe is also passionate about the ways that public health policies shape individual health outcomes. She has a master’s degree in population health from University College London and recently completed a social science research methods master's degree at Cardiff University. She is currently working on her PhD in medical sociology. Her research examines people's experiences of accessing, using, and discontinuing long-acting reversible contraception.
When she’s not working, Smythe enjoys dancing, photography, and spending time with her family and her cat, Finnegan.

Lindsey Konkel
Author
Lindsey Konkel is an award-winning freelance journalist with more than 10 years of experience covering health, science, and the environment. Her work has appeared online and in print for Newsweek, National Geographic, Huffington Post, Consumer Reports, Everyday Health, Science, Environmental Health Perspectives, UCSF Magazine, American Association for Cancer Research, and others.
She previously worked as an editor and staff writer at Environmental Health News. She holds a master’s degree in journalism from NYU’s Science, Health and Environmental Reporting Program and a bachelor’s degree in biology from College of the Holy Cross.
Konkel lives in Haddon Township, New Jersey, with her husband, daughter, three cats, and dog. When she isn't writing, she handles social media and content marketing for a small veterinary clinic she started with her husband, Neabore Veterinary Clinic.