12 At-Home Sore Throat Treatments We Love And Why They Work

The 12 Best Sore Throat Treatments That Actually Work

A sore throat is one of the most common (yet most uncomfortable) ailments people face, especially during cold and flu season. Whether it’s sparked by a viral infection, allergies, dry indoor air, or even overusing your voice, that telltale scratch or burn can make it hard to eat, talk, or sleep. The good news is that most sore throats are short-lived and can be safely managed at home with the right treatments. However, choosing the best remedies — from lozenges and sprays to teas and humidifiers — can make all the difference in how quickly and comfortably you recover.

Because the cause of a sore throat matters, we spoke with three doctors to help you navigate what actually works: Nicholas Bower, DO, doctor and regional medical director at University of Maryland Urgent Care (part of the academic University of Maryland Medical System) with multiple locations in Maryland; Jefferey Chester, DO, doctor and medical director at The Ohana Luxury Addiction Treatment Center based in Kailua Kona, Hawaii; and Robert Biernbaum, DO, doctor and chief medical officer for WellNow Urgent Care with multiple locations in New York. In this article, these doctors weigh in on how to tell when a sore throat is a symptom of something more serious (like tonsillitis, acid reflux, or strep), plus explain when over-the-counter (OTC) treatments are enough versus when it’s time to see a doctor. We also asked them for input on ingredients, pain management, and common pitfalls, such as overusing numbing sprays that mask pain but don’t address the root cause.

Armed with their guidance and our own research, this guide breaks down the best evidence-based sore throat treatments you can buy right now. From honey-based remedies to lozenges to salt-water rinses, every option here was chosen with safety, effectiveness, and practicality in mind, so you can soothe discomfort quickly and confidently, while also considering when it’s worth seeking medical care.

When to See a Doctor

Most sore throats clear up on their own, but sometimes they signal something more serious. “For children, any sore throat accompanied by fever should be evaluated by a pediatrician, primary care, or urgent care provider to rule out streptococcal pharyngitis (strep throat),” says Dr. Bower, noting that strep is contagious and requires antibiotics to prevent complications. In adults, he adds, “Mild or short-lived fevers early in a viral illness are usually less concerning, but if fever develops several days in or lasts beyond 72 hours, that can signal a bacterial infection.” Dr. Biernbaum warns to “call 911 or seek emergency medical care if you’re having difficulty breathing, swelling in your face or tongue, or chest pain,” since these may indicate life-threatening airway issues like epiglottitis or abscesses. And if sore throats are chronic or recurrent, “it may be a good idea to see a specialist,” says Dr. Chester.

Our Top Picks for Sore Throat Treatments

sore throat spray

Best Spray for Fast Relief

Chloraseptic Max Sore Throat Spray

Pros

  • Fast-acting pain relief that numbs the throat almost immediately on contact
  • Helps ease pain when swallowing
  • Targeted pain relief
  • Easy to use and can be reapplied several times a day within label directions

Cons

  • Frequent reapplication may be needed
  • Does not treat the cause of pain
  • Potential irritation with overuse
  • Unsuitable for some (young children or those with sensitivities to phenol)

Key Specs

  • Type: Topical throat spray and throat anesthetic
  • Active ingredients: Phenol (used as an oral analgesic-antiseptic)
  • Flavored: Wild berries
  • Who it’s for: Adults and children ages 3 and up

The reason Chloraseptic Max Strength is often recommended for fast relief lies in how topical anesthetics like phenol work. It numbs nerve endings in the throat almost immediately on contact, helping reduce pain in seconds. Because it’s sprayed directly on the back of the throat, it acts locally rather than relying on systemic absorption, providing quick relief. 

That said, the relief is temporary. Sprays like Chloraseptic help mask pain and make swallowing less uncomfortable, but they don’t treat the underlying cause of the throat irritation (like from viral, bacterial, or environmental causes). Sprays like this one act quickly but might not maintain the anesthetic effect as long as some lozenges or slower-dissolving agents, because the exposed surface area and binding time differ. 

“OTC numbing sprays, such as Chloraseptic [with] phenol, provide short-term pain relief and are safe for adults when used as directed,” explains Bower. “For severe pain or difficulty swallowing, prescription viscous lidocaine may be appropriate under medical supervision but avoid swallowing it in large amounts due to potential systemic absorption.”

sore throat and cough lozenges

Best Medicated Lozenges

Cepacol Extra Strength Sore Throat

Pros

  • Benzocaine provides strong numbing relief
  • Helps reduce throat pain fast by temporarily desensitizing the nerves
  • Acts over time while dissolving
  • Combines menthol for a cooling sensation
  • Easy to carry and dose

Cons

  • Risk of local irritation or burning-tingling
  • Rare but serious side effects from benzocaine lozenges have been reported

Key Specs

  • Type: Medicated throat lozenge
  • Active ingredients: Benzocaine
  • Flavored: Various flavors to choose from, like honey-lemon, mixed berry, cherry, and sugar-free variants
  • Who it’s for: Adults and children over 6 years old

Cepacol Extra Strength lozenges leverage benzocaine, a topical anesthetic that works by numbing local nerve endings in the throat, reducing the sensation of pain and making swallowing more comfortable. Because the active ingredient (benzocaine) is delivered right where the discomfort is, the effect tends to be fast and localized. Medicated lozenges like Cepacol may be more effective than nonmedicated ones in reducing the sensation of throat pain, especially when swallowing is painful, because they provide both physical lubrication and targeted numbing directly to the inflamed tissue as the lozenge dissolves. But Biernbaum reminds us, “Over-the-counter [treatments] containing numbing agents like benzocaine or menthol may provide temporary relief from sore throat discomfort. However, these sprays do not cure or speed up the duration of a sore throat.”

And because they release the anesthetic over time while dissolving in the mouth, Cepacol lozenges can maintain a local soothing effect that typically lasts several minutes. While the continuous lubrication of a lozenge can help reduce irritation and dryness, throat sprays offer more immediate (yet short-lived) relief.

sore throat spray

Best Sore Throat Treatment for Kids

Beekeeper’s Naturals Kids Propolis Throat Spray

Pros

  • Offers targeted delivery as a spray
  • Uses a simple ingredient list with no artificial colors, preservatives, or refined sugars
  • Contains propolis, which has antimicrobial, anti-inflammatory, and antiviral properties

Cons

  • Combination of propolis and honey may trigger allergic reactions in individuals sensitive to bee products
  • Limited clinical evidence of efficacy in children
  • Only offers symptom relief; doesn’t cure infections or reduce inflammation

Key Specs

  • Type: Oral throat spray
  • Active ingredients: Propolis extract, buckwheat honey, non-GMO vegetable glycerin, purified water
  • Flavored: Sweetened with buckwheat honey
  • Who it’s for: Children ages 2 and up
For parents looking for a gentler, age-appropriate option to soothe throat discomfort, this propolis throat spray offers an alternative to hard lozenges (which can pose choking risks in younger kids). Because it’s delivered as a spray, it can reach the back of the throat and coat irritated tissues with ingredients known for their traditional soothing and antimicrobial properties. It’s important to note that propolis sprays are said to help alleviate upper respiratory symptoms in adults, although pediatric-specific data are more limited.

This spray should not replace a medical evaluation. It is best viewed as supportive, symptomatic relief — the kind that’s helpful for mild throat irritation or in the early stages of a cold. Caregivers should monitor for allergic reactions (especially in children with bee or pollen sensitivities), avoid excessive use, and consult a pediatrician if symptoms worsen or are accompanied by fever, trouble swallowing, or swollen glands.

sore throat gargle

Best Gargle Rinse

Betadine Sore Throat Gargle

Pros

  • Active ingredient povidone-iodine (PVP-I) is a powerful antiseptic that can help reduce bacteria and viruses in your throat
  • Coats the back of your throat for more focused relief compared with swallowing a pill
  • Easy to use 

Cons

  • Overuse or frequent gargling may lead to local irritation or adverse effects
  • Contains a relatively high alcohol content, which might sting or dry mucous membranes in sensitive users

Key Specs

  • Type: Antiseptic oral rinse
  • Active ingredients: Povidone-iodine
  • Flavored: Medicated mint flavor
  • Who it’s for: Adults and children 12 years and older
Betadine Sore Throat Gargle is a medicated rinse that helps fight bacteria and viruses right where soreness starts. Its active ingredient, povidone-iodine, works quickly to kill germs on contact and ease irritation. Because you gargle it rather than swallow it, the formula coats the throat directly, providing fast, targeted relief when you need it most.


Betadine is best used as a supportive treatment rather than a primary cure. It doesn’t replace antibiotics for bacterial infections or directly address pain and inflammation, but it can help manage symptoms when used correctly. Users should also stick to the recommended frequency and concentration. Overuse might lead to irritation or impact iodine exposure (important for those with thyroid conditions).

Best Salt-Water Alternative

H2Ocean Healing Rinse Natural Sea Salt Oral Care

$9.99 at Amazon
$10.99Now 9% Off

Pros

  • Delivers salt-based cleansing and rinsing benefits in a ready-to-use formula
  • Includes mild soothing agents and sea minerals that may help freshen and calm irritated mucous membranes
  • Doubles as an oral rinse and gargle, offering flexibility for throat or oral discomfort

Cons

  • Some users may find the saltiness or taste strong or slightly uncomfortable
  • Overuse could lead to mild dryness or throat irritation

Key Specs

  • Type: Oral rinse (mouthwash)
  • Active ingredients: Sea salt (sodium chloride) solution, supplemented with trace minerals and flavoring
  • Flavored: Mild saline, sea salt taste
  • Who it’s for: All ages

When a traditional saltwater gargle feels like too much effort, H2Ocean Healing Rinse offers an easy alternative. Preformulated with sea salt and minerals, it delivers similar cleansing benefits without the need for measuring or mixing. That means it can gently rinse away irritants, loosen mucus, and help freshen the throat and mouth with minimal effort. It’s especially handy for those who want the soothing effects of a saltwater gargle without all the prep work.

While saline rinses and gargles like H2Ocean can help clear mucus, calm irritation, and make a sore throat feel better, they work more by washing things away than by “curing” anything. Research shows that gargling with saline early on in an illness may help rinse out some of the germs in your throat and even shorten how long symptoms stick around.

Just make sure to use sterile or distilled water (not straight from the tap), follow the directions on the label, and don’t overdo it. Too much can actually dry out your throat and make it feel more irritated.

Best Herbal Tea for Throat Soothing

Traditional Medicinals Throat Coat Tea

$5.32 at Amazon

Pros

  • Uses a blend of herbs known for soothing throat discomfort
  • Comes as a simple tea; no sugars, no strong chemicals, and flexible dosing
  • Easy to incorporate into a self-care routine
  • Provides hydration

Cons

  • Relief is symptomatic and mild (not strong enough for severe pain or serious infection)
  • Herbs may interact with medications or conditions
  • Taste may not appeal to everyone

Key Specs

  • Type: Herbal tea
  • Active ingredients: Licorice root, slippery elm bark, marshmallow root
  • Flavored: Natural herb mix; no artificial flavoring
  • Who it’s for: Adults and children over 12
Traditional Medicinals Throat Coat Tea is a gentle, plant-based option intended to support throat comfort. When steeped in hot water, its combination of herbs like slippery elm and marshmallow creates a soothing film that coats irritated throat tissues. Licorice root has a mild, soothing effect and has been historically used for respiratory and throat ailments, and there is some evidence to suggest that it can provide short-term relief from a sore throat.


This tea’s biggest benefit comes from keeping you hydrated, which helps thin mucus and soothe throat irritation. Because it’s caffeine-free, it won’t dry you out or interfere with rest the way some teas can. Still, it’s important to watch for potential sensitivities, especially to licorice root, which may raise blood pressure with frequent use.

humidifier

Best Humidifier for Dry Air Relief

Levoit Top Fill Humidifier

Pros

  • Easy to refill and maintain
  • Quiet operation and long runtime, suitable for overnight use in bedrooms or offices
  • Adjustable mist settings

Cons

  • If not cleaned regularly, can develop buildup of bacteria and mold in the reservoir or vapor path
  • Only addresses environmental contributors to throat irritation (dry air), not infections, allergies, or deeper causes

Key Specs

  • Type: Humidifier
  • Active Ingredients: Not applicable
    Flavored: Not applicable
  • Who It’s For: Households dealing with dry indoor air or anyone whose throat discomfort is worsened by environmental dryness
The Levoit Top Fill Humidifier is a practical option for easing sore throat discomfort caused or worsened by dry indoor air. Its ultrasonic cool-mist design adds moisture to the environment quietly and efficiently. This can help soothe irritated throat tissues and make breathing more comfortable, especially during winter or when heating systems dry out the air. Maintaining indoor humidity between 40 and 60 percent can help keep the air from drying out your nasal passages and throat.

Because the Levoit model features a top-fill tank and easy-clean design, it’s simple to maintain and refill, making it a convenient choice for bedrooms or home offices.

A humidifier isn’t a cure for a sore throat caused by illness, but it can make you feel a lot more comfortable while you recover. By adding moisture back into dry indoor air — especially in homes with heat or air-conditioning — it can help keep your throat from getting scratchy or irritated. Just don’t forget to clean the tank often to avoid bacteria or mold buildup.

cough drops

Best All-Natural Lozenges

Ricola Original Natural Herb Cough Drops

Pros

  • Uses a blend of herbs and menthol to soothe the throat
  • Acts as a cough suppressant and gentle oral anesthetic
  • Individually wrapped for on-the-go throat relief 

Cons

  • Some versions contain sugar

Key Specs

  • Type: Lozenge
  • Active ingredients: Menthol
  • Flavored: Herbal flavor using Swiss herb blend (peppermint, lemon balm, and thyme)
  • Who it’s for: Adults and children ages 6 years and older
Ricola Original Natural Herb Cough Drops offer gentle, over-the-counter relief for sore throat and mild cough symptoms. Each drop contains menthol along with a blend of 10 Swiss alpine herbs that help soothe irritation and provide a light cooling effect. This tried-and-true product, with its straightforward formula, will appeal to those who prefer a natural option without harsh numbing agents.
sore throat lollipops

Best Lozenge Alternative for Kids

Beekeeper’s Naturals Throat Soothing Lollipops

Pros

  • Offers throat soothing in a fun lollipop form
  • Contains propolis, honey, zinc, and vitamin D
  • Only 2 g of sugar per serving

Cons

  • Propolis can cause allergic reactions in those sensitive to bee products
  • Not ideal for very young children

Key Specs

  • Type: Lollipop
  • Active ingredients: Propolis extract, wildflower honey, zinc, vitamin D
    Flavored: Naturally sweetened with honey
  • Who it’s for: Children over 4 years old
Beekeeper’s Naturals Kids Throat Soothing Lollipops offer a creative alternative for soothing mild throat irritation in children, especially in age groups where hard lozenges might be risky. Because they dissolve slowly, they can coat the throat like honey and provide a mild antimicrobial, anti-inflammatory effect. Propolis extracts, in particular, show antiviral effects.

While the lollipop format hasn’t been studied as extensively as sprays or lozenges, it’s a fun option for children who aren’t ready for traditional throat drops or pills. As with any over-the-counter remedy, it’s wise to keep an eye on symptoms and reach out to a pediatrician if they linger or worsen.

cough and sore throat medicine

Best Cough Syrup With Sore Throat Focus

Robitussin Adult Maximum Strength Severe Cough + Sore Throat Relief Medicine

Pros

  • Cough suppressant and a sore throat pain reliever in one formula
  • Liquid syrup format can be easier to swallow
  • Effective for more severe symptoms

Cons

  • Risk of ingredient overlap with other OTC products (like acetaminophen) raises the chance of overdose or side effects
  • Not ideal for long-term use or for people with contraindications (like liver disease, certain medications)

Key Specs

  • Type: Liquid cough syrup
  • Active ingredients: Dextromethorphan HBr (cough suppressant) and Acetaminophen (pain reliever and fever reducer)
    Flavored: Standard flavoring
  • Who it’s for: Adults and children 12 years and older

Robitussin Adult Maximum Strength Severe Cough + Sore Throat Relief is formulated for adults experiencing both a persistent cough and throat pain. The liquid formula coats the throat and provides relief through its combination of a cough suppressant (dextromethorphan) and a pain reliever (acetaminophen). This dual approach can help reduce discomfort and make it easier to rest and recover when a cough and sore throat occur together.

Because it’s a combination medication, it’s important to read the label carefully and avoid using other products that contain acetaminophen to prevent overdose. People with liver disease, certain medical conditions, or sensitivity to these ingredients should consult a healthcare provider before using it.

vicks vaporub

Best Menthol Rub for Comfort

Vicks VapoRub

Pros

  • Provides a rapid cooling sensation that many users find soothing to irritated airways and chest tightness
  • Offers multisymptom relief (cough, nasal discomfort, minor throat irritation) through its blend of menthol, camphor, and eucalyptus oils
  • Widely available, affordable, and simple to apply topically

Cons

  • May irritate skin
  • Not safe for use in very young children (particularly under 2 years)

Key Specs

  • Type: Topical ointment
  • Active ingredients: Contains menthol, camphor, eucalyptus oil (in a petrolatum base)
  • Flavored: No oral flavoring; aromatic (menthol-camphor scent)
  • Who it’s for: Adults and children 2 years and older

Vicks VapoRub has long been a household staple for providing topical comfort when a sore throat or cough flares up. Its menthol, camphor, and eucalyptus components generate a cooling aromatic effect that many find soothing, especially for chest and throat discomfort. Clinical trials (although older and mostly in children) support its benefits. 

Because VapoRub is topical and external, its risk profile is relatively mild. However, users should avoid applying it to broken or sensitive skin, near the nostrils or eyes, or using it on infants under the age of 2. 

Best All-in-One Relief

Mucinex Fast-Max Liquid Gels, Cold, Flu, & Sore Throat

$15.97 at Amazon

Pros

  • Multisymptom relief in one gel
  • Rapid symptom control
  • Widely available in drugstores and online

Cons

  • Potential for side effects and interactions with active ingredients

Key Specs

  • Type: Liquid gel capsule
  • Active ingredients: Acetaminophen (pain reliever and fever reducer), dextromethorphan HBr (cough suppressant), guaifenesin (expectorant), and -phenylephrine HCl (nasal decongestant)
  • Flavored: No
  • Who it’s for: Adults and children 12 years and older (not recommended for children under 12)

Mucinex Fast-Max Liquid Gels for Cold, Flu, & Sore Throat is tailored for adults seeking an all-in-one approach to symptom relief. Its formulation targets multiple pathways: pain, fever, congestion, cough, and mucus. So rather than juggling several pills, you take one that covers the essentials. The inclusion of acetaminophen helps ease throat pain and reduce fever, while the expectorant and decongestant work together to make breathing a little easier.

It’s important to note that combination products always come with trade-offs. Because it packs several active ingredients, users must be careful not to overlap with other medications (especially those with acetaminophen). People with liver issues, heart disease, or high blood pressure should check with a doctor or pharmacist before use, and always read the label and follow directions closely to stay within safe limits.

Comparison Table

Superlative
Type
Active Ingredients
Flavored
Who It’s For
Buy Now
Best spray for fast relief
Topical throat spray and throat anesthetic
  • Phenol
Wild berries
Adults and children ages 3 and up
Best medicated lozenges
Medicated throat lozenge
  • Benzocaine 

Various flavors to choose from, like honey-lemon, mixed berry, cherry, and sugar-free variants

Adults and children over 6 years old
Best sore throat treatment for kids
Oral throat spray
  • Propolis extract
  • Buckwheat honey
  • Non-GMO vegetable glycerin
  • Purified water
Sweetened with buckwheat honey
Children ages 2 and up
Best gargle rinse
Antiseptic oral rinse
  • Povidone-iodine 
Medicated mint flavor
Adults and children 12 years and older
Best salt-water alternative
Oral rinse (mouthwash)
  • Sea salt (sodium chloride) solution, possibly supplemented with trace minerals and flavoring 
Mild saline, sea salt taste
All ages
Best herbal tea for throat soothing
Herbal tea
  • Licorice root
  • Slippery elm bark
  • Marshmallow root
Natural herb mix; no artificial flavoring
Adults and children over 12
Best humidifier for dry air relief
Humidifer 
Not applicable 
Not applicable
Households dealing with dry indoor air, especially during heating seasons, or anyone whose throat discomfort is worsened by environmental dryness
Best all-natural lozenges
Lozenge
  • Menthol
Herbal flavor using Swiss herb blend (peppermint, lemon balm, and thyme) 
Adults and children ages 6 years and older
Best lozenge alternative for kids
Lollipop
  • Propolis extract
  • Wildflower honey
  • Zinc
  • Vitamin D
Naturally sweetened with honey
Children over 4 years old
Best cough syrup with sore throat focus
Liquid cough syrup
  • Dextromethorphan HBr (cough suppressant)
  • Acetaminophen (pain reliever and fever reducer)
Standard flavoring
Adults and children 12 years and older
Best menthol rub for comfort
Topical ointment
  • Contains menthol, camphor, eucalyptus oil (in a petrolatum base)
No oral flavoring; aromatic (menthol-camphor scent)
Adults and children 2 years and older
Best all-in-one relief


Liquid gel capsule
  • Acetaminophen (pain reliever and fever reducer)
  • Dextromethorphan HBr (cough suppressant)
  • Guaifenesin (expectorant)
  • Phenylephrine HCl (nasal decongestant)
No
Adults and children 12 years and older (not recommended for children under 12)

How We Selected the Best Treatments for Sore Throats

To find the best sore throat treatments available, we consulted three doctors to understand which remedies truly help and which ones to skip. We evaluated a wide range of OTC options, from lozenges and sprays to teas, humidifiers, and home remedies that support comfort and healing.

When choosing the best sore throat treatments, we prioritized options that meet the highest standards of safety, effectiveness, and accessibility. Each recommendation contains active ingredients backed by scientific research — such as menthol, benzocaine, honey, or pectin — and demonstrates a clear benefit for soothing throat irritation, reducing inflammation, or supporting hydration. We also considered user experience, including taste, ease of use, and relief.

The result is a curated list of doctor-approved sore throat treatments that combine evidence-based relief with practical comfort, so you can recover faster and feel better safely.

What to Look for in a Sore Throat Treatment

The best sore throat treatment depends on what’s causing your symptoms. Treating the underlying cause helps ensure you’re soothing your throat and helping it heal.

Once you know the likely cause, look for treatments with proven soothing ingredients. Biernbaum explains, “For a simple sore throat, pain can be improved with acetaminophen or ibuprofen. These can take 30 minutes to an hour to take effect, but they can be taken on a schedule to control the pain.” For faster relief, Biernbaum adds, “There are OTC topical pain relievers for sore throat like Cepacol or Chloraseptic that contain topical benzocaine and menthol, which have been found to improve sore throat symptoms. The topical pain relievers have a rapid onset of a couple of minutes.” You can also look for lozenges with honey, pectin, or other demulcents that coat and calm irritated tissues.

Just remember to use numbing sprays sparingly, as they can ease pain briefly but won’t treat the root cause and can mask worsening symptoms.


Supportive care goes a long way, too. “Individuals should get plenty of rest and stay hydrated with clear liquids to improve their sore throat,” says Biernbaum. “Gargling with warm salt water can also help alleviate symptoms.” If your sore throat is caused or worsened by dry air, a humidifier can restore moisture and prevent irritation. And when discomfort interferes with eating, sleeping, or talking, that’s the time to add an OTC pain reliever such as acetaminophen or ibuprofen for broader symptom control. The right treatment balances targeted relief with simple self-care, so you can feel better faster and let your throat truly recover.

What’s the Difference Between Strep Throat and a Viral Sore Throat?

Not all sore throats are created equal, and understanding the difference between viral and bacterial causes is key to getting the right treatment. “Clinically speaking, a sore throat refers to inflammation, pain, scratchiness, or irritation in the pharyngeal (posterior throat) area — with or without swallowing,” explains Bower. He says most sore throats (roughly 80 percent) are caused by viruses like rhinovirus, coronavirus, the flu, Coxsackievirus (hand, foot, and mouth disease), or Epstein-Barr (mononucleosis). Bacteria, which cause infections such as strep throat, are responsible for roughly 10 percent of sore throats. Bower points out that allergies and irritants cause about the same percentage of sore throats.

If you have a sore throat, how do you tell the difference? Viral sore throats often develop gradually and are accompanied by cold-like symptoms, such as congestion, cough, or a runny nose.

These typically improve within a few days and can be managed with rest, fluids, and over-the-counter treatments. Strep throat, on the other hand, tends to appear suddenly and may cause severe pain when swallowing, swollen lymph nodes, and fever without the nasal symptoms typical of viral infections.

“A careful history and physical by a provider almost always points you in the right direction,” says Bower. “The timing, pattern, and associated symptoms tell the story, and a quick strep or viral test can confirm or rule out concerning pathogens.”

It’s important to point out that environmental or lifestyle factors can also mimic infection. “Making a connection to other factors in the history is critical,” Bower adds. “For example, a patient having sore throats in the evening or morning, when consuming large meals close to lying down, could surely indicate acid reflux as the cause.” In other words, while most sore throats are viral and self-limiting, persistent or severe symptoms (especially with high fever, rash, or difficulty swallowing) should prompt a visit to your healthcare provider for accurate testing and treatment.

What Should You Avoid When Treating a Sore Throat?

While treating a sore throat, it’s just as important to know what to avoid. “There are certain foods and drinks that can worsen the irritation, like spicy foods and acidic food and drinks,” says Biernbaum. “Alcohol and caffeine should also be avoided because they cause dehydration. Smoking can worsen irritation as well.” Overusing menthol lozenges can also backfire. They may dry out the throat or temporarily mask a worsening infection, delaying proper care.

“Don’t use alcohol based mouthwashes. Don’t smoke,” Chester adds. “Avoid straining your voice.” These irritants can dry out or inflame already sensitive tissues, prolonging healing. Instead, stick to soothing, nonacidic liquids like warm tea with honey, broths, and plenty of water to stay hydrated and support recovery.

Is It Safe to Combine Home Remedies and Medications for a Sore Throat?

When your throat hurts, it’s natural to reach for more than one remedy, but combining treatments requires care. Using several OTC products at once can increase your risk of overlapping ingredients, side effects, or drug interactions. For instance, many multisymptom cold or flu medicines already contain acetaminophen or ibuprofen, so adding an extra dose separately can lead to unintentional overdose or stomach irritation.

Lozenges, sprays, and syrups that include benzocaine or other numbing agents should also be used sparingly to avoid overuse or masking symptoms that warrant medical attention.


If you’re combining a pain reliever (like acetaminophen or ibuprofen) with a topical spray or lozenge, it’s generally safe as long as you follow dosing instructions and check for ingredient overlap. Hydration, humidifiers, and saltwater gargles can safely be used alongside medications and often enhance comfort. When in doubt, pharmacists can help you review ingredients and avoid interactions. As Biernbaum notes, individuals should “always check the boxes on OTC medications to ensure it is a medication they can take with their medical conditions or demographics.” In short: Layering remedies can help you feel better faster, but smart, label-aware use is essential for staying safe.

FAQ

Is honey safe and effective for kids and adults?
Yes, honey can be a safe and effective sore throat remedy for both adults and children over age 1. “Some herbal remedies, such as honey and lemon tea, may provide relief for sore throats,” explains Biernbaum. “Honey has natural antimicrobial properties and can soothe the throat, while lemon provides vitamin C and antioxidants.” Studies suggest honey improved cough frequency and symptom severity in upper respiratory infections compared with usual care. Its thick texture coats the throat, reducing irritation, and its antimicrobial compounds, like hydrogen peroxide and methylglyoxal, may help fight infection. However, honey should never be given to infants under 12 months because it can contain Clostridium botulinum spores, which cause infant botulism. For everyone else, a spoonful of honey or honey-lemon tea can be a soothing, low-risk way to ease sore throat discomfort.
Numbing sprays can provide quick, temporary relief for sore throats, but they’re not a cure. According to Chester, “Numbing sprays are helpful for short-term relief. However, they won’t address the root cause. For example, if the sore throat is caused by a bacterial infection, such as strep throat, it's essential to consult a doctor to receive antibiotics to treat the infection.” Most sprays contain ingredients like benzocaine or phenol, which can dull pain by numbing throat tissues, but they do not treat underlying infections. If symptoms persist beyond a few days, worsen, or are accompanied by fever or swollen lymph nodes, it’s important to seek medical evaluation to rule out bacterial causes that require prescription treatment.
Yes, humidifiers can help ease sore throat discomfort, especially when dryness is a contributing factor. By adding moisture to the air, humidifiers prevent the throat and nasal passages from drying out, which can reduce irritation and promote healing. Research suggests that using heated, humidified air can help reduce the severity and incidence of sore throat symptoms, as shown in a clinical study where patients exposed to humidified air experienced significantly less throat discomfort than those who breathed dry air. While humidifiers don’t cure infections, they can make breathing and swallowing more comfortable, especially during cold, dry months or when using indoor heating.
Yes, saltwater gargles are a time-tested and evidence-backed remedy for soothing sore throats. According to Bower, “Local soothing remedies such as warm saltwater gargles (about ½ teaspoon of salt in 8 ounces of warm distilled or sterile water) can reduce swelling, clear mucus, and soothe pain. Some patients also like to use a fifty-fifty mix of warm water and 3 percent hydrogen peroxide, though this can cause mild irritation.” Bower continues, “Evidence supports salt water as safer and equally effective for routine use.”

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Ysolt Usigan

Ysolt Usigan

Author

Ysolt Usigan is a veteran writer, editor, and commerce journalist with more than a decade of experience creating lifestyle, health, wellness, and shopping content for brands including BestProducts.com, Good Housekeeping, Woman's Day, WhatToExpect, SheKnows, and RetailMeNot.

Ysolt specializes in product testing and reviews, shopping guides, and service journalism that help readers make smart, confident choices.

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Simran Malhotra, MD

Medical Reviewer
Simran Malhotra, MD, DipABLM, CHWC, is a triple board-certified physician in internal medicine, hospice and palliative care, and lifestyle medicine, as well as a certified health and wellness coach. She is currently practicing part time as an inpatient palliative care physician at Medstar Health after serving as the palliative care medical director at Franklin Square Medical Center in Baltimore for a little over four years.

Dr. Malhotra completed her internal medicine residency at Medstar Franklin Square Medical Center, where she also served as chief resident in 2015. She completed her fellowship in hospice and palliative medicine at Johns Hopkins Hospital in 2016. She was named Top Doc in Palliative Medicine in 2019 and 2020 by Baltimore Magazine.

On a personal note, she is a BRCA1 previvor with a strong family history of breast and female reproductive cancers, and underwent a risk-reducing bilateral mastectomy and total hysterectomy in 2020 at 32 years old. After learning about her own genetic risk of cancer, and grounded in her professional experiences in palliative care, she founded Wellness By LifestyleMD, a platform where she works with and educates women at high risk for cancer with or without genetic mutations on the powerful impact that positive lifestyle changes can have on their quality of life and even longevity.

In addition to being a diplomate of the American College of Lifestyle Medicine, she completed the T. Colin Campbell plant-based nutrition certification in 2019, the CHEF culinary coaching certification in 2020, and the WellCoaches health and wellness coaching certification in 2022. She is a member of the ACLM women’s health member interest group and serves as the co-chair of the breast cancer subcommittee.

Malhotra has been featured on several blogs and podcasts, where she has shared her unique perspectives and experiences from palliative care as well as from being a genetic mutation carrier who is passionate about using lifestyle as medicine.

Orlando de Guzman

Fact-Checker

Orlando de Guzman is a writer and editor with expertise in health and environmental news. He has a background in investigative and science journalism and has worked on documentary films about war and trauma, health, sanitation, and the changing climate around the world. His interest in health and medicine started after an early career as a medical and legal translator.

De Guzman is a longtime health and fitness enthusiast who is interested in nutrition, diet, and mental health. He participates in endurance sports and cross-trains in several traditions of martial arts from Southeast Asia. De Guzman is interested in how the progressively complex movements of martial arts training can improve cognition and mental well-being, especially for those with PTSD and for those approaching middle age and beyond.

De Guzman has a dual B.A. in communications and international studies from the University of Washington in Seattle. He is committed to factual storytelling and evidence-based reporting on critical choices that affect our planet.

Katie Tuttle

Editor

Katie Tuttle is an editor and writer specializing in food, nutrition, and product testing. Her work has appeared in EatingWell, Food & Wine, The Spruce Eats, and Real Simple. She has written about meal kits, kitchen tools, fitness, and wellness, and has tested and reviewed a wide range of products, with a particular focus on meal delivery services and their impact on nutrition and convenience.

Beyond food, Katie has covered fitness and wellness topics, drawing from her own experience as a powerlifter and an occasional runner. She’s always interested in how products and services can make healthy living more accessible and practical.

When she’s not researching or writing, Katie is usually surrounded by houseplants or spending time with a foster dog. She firmly believes there’s no such thing as too many books or too much coffee.

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Resources
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