What Is Dementia?

Dementia is not a disease. Instead, it’s a syndrome — a set of symptoms — that occurs when neurons (nerve cells) in the brain stop working, lose connections with other brain cells, and die.
Dementia ranges in severity from mild to severe. In the final stages, people become completely incapable of caring for themselves and require around-the-clock help with the most basic aspects of daily living.
Up to half of all men and women ages 85 and older (sometimes called “the oldest old”) have some form of dementia, yet experts don’t consider it a normal part of aging. Many people live into their nineties with their cognitive abilities intact.
Some people with dementia may be unable to control their emotions, or they may exhibit personality changes.
Dementia is different for everybody. Kalisha Bonds Johnson, PhD, RN, of Emory University’s Nell Hodgson Woodruff School of Nursing in Atlanta explains how.
Next up video playing in 10 seconds
If You Know One Person With Dementia…
Stages of Dementia
Outlining the stages of dementia, however, can be useful for people considering their future caregiving needs, hoping to enlist in clinical trials, or otherwise planning ahead.
Each of the four most common types of dementia — Alzheimer’s, vascular dementia, Lewy body dementia, and frontotemporal disorders — has early symptoms that can be telling. Unlike the short-term memory loss of Alzheimer’s, for instance, vascular dementia may reveal itself as difficulty making plans or decisions.
Signs and Symptoms of Dementia
Dementia involves impairment of core cognitive functions — such as memory, language skills, visual perception, the ability to focus and pay attention, and the ability to reason and solve problems — that’s severe enough to affect a person’s ability to do normal everyday tasks.
An accurate diagnosis is the first step toward getting the right kind of treatment and support for your dementia.
Causes and Risk Factors of Dementia
Dementia occurs when neurons (nerve cells) in the brain stop working, lose connections with other brain cells, and die. Researchers are still working to understand why this happens and are investigating the role that genetics, lifestyle, and environment all play as dementia risk factors.
Scientists have observed an association between certain kinds of dementia and high levels of proteins in the brain, as with the protein beta-amyloid (plaques) in Alzheimer’s disease.
Lewy body dementia, the third-most-common form of dementia, is associated with abnormal deposits of a protein called alpha-synuclein. In a healthy brain, alpha-synuclein helps neurons communicate. But when alpha-synuclein begins to clump inside neurons, forming so-called Lewy bodies, brain function is impaired, impacting thinking, movement, behavior, and mood.
How Is Dementia Diagnosed?
The right diagnosis, though, is critical to getting the best treatment. Typically, this process starts with your primary care doctor, although specialists like a neurologist, neuropsychologist, or geriatrician may play a role.
The first task is ruling out treatable or reversible conditions with symptoms that can mimic dementia, such as depression or a thyroid problem. Your doctor will take a detailed medical history, conduct a physical exam and a neuropsychological assessment, and order lab tests.
Neuropsychological assessments help doctors see cognitive patterns that may indicate the presence of a particular brain disorder. These tests look at cognitive skills like memory, problem solving, language abilities, and focus.
Treatment and Medication Options for Dementia
There is currently no cure for any of the progressive brain diseases that cause dementia. But there are several potential ways to treat dementia, depending on your underlying condition.
Medication Options
Disease-Modifying Monoclonal Antibody Therapies
Some newer drugs may slow down the process of cognitive decline in the early stages of Alzheimer’s disease. These drugs — lecanemab (Leqembi) and donanemab (Kisunla) — work by preventing plaques from clumping in the brain.
Disease-Modifying Monoclonal Antibody Examples
- Lecanemab (Leqembi)
- Donanemab (Kisunla)
Cholinesterase Inhibitors
Cholinesterase Inhibitors Examples
- Donepezil (Aricept)
- Rivastigmine (Exelon)
- Galantamine (Razadyne)
Blood Pressure and Cholesterol Medication
Antidepressants
Cognitive Behavioral Therapy
There are also hundreds of clinical trials in the United States looking at dementia. Investigators working with people online and at centers around the country are studying both pharmaceutical and nonpharmaceutical interventions.
Lifestyle Changes for and Prevention of Dementia
Lifestyle Changes for Dementia
Reduce Stress
People with dementia may improve their quality of life by focusing on their overall well-being and taking steps to reduce stress, simplify tasks, and reduce clutter at home.
Eat Well and Exercise
You can enhance your physical health by being physically active, eating well, and taking part in activities that involve social interaction or stimulate your brain.
Stay Social and Find Meaning
To boost psychological health, relationships are key. Having close friends who can provide emotional support can lift your feelings of well-being and self-worth.
People with dementia can also nourish their spiritual health by taking part in meaningful activities — whether that means outings with family and friends or quiet, meditative moments alone pursuing a hobby like yoga.
Caregivers can help improve quality of life for people with dementia by knowing the best ways to communicate and having strategies to overcome cognitive or behavioral challenges. For instance, presenting complex tasks a step at a time can lead to a greater chance of success and foster feelings of confidence.
Keep a Routine
Prevention of Dementia
While your genetic makeup is known to play a role in dementia risk, in most cases, it’s just one piece of the puzzle. Researchers are actively investigating lifestyle and environmental factors that may increase or decrease your risk of developing dementia.
Keep Your Heart Healthy
Stay Social
Get Better Sleep
How Long Does Dementia Last?
Dementia is an ongoing condition that becomes more severe over time. How quickly your dementia progresses will depend on many factors, including the type of dementia you have, and varies from person to person.
People with vascular dementia typically live for about five years, and are more likely to die from a stroke or heart attack than from their dementia. People with Lewy body dementia typically live for about six years.
Complications of Dementia
Dementia is a progressive neurodegenerative syndrome that affects cognitive, behavioral, and functional abilities. As the disease advances, individuals frequently develop a range of medical and functional complications that significantly contribute to morbidity, hospitalizations, and mortality. Many of these complications arise from declining neurological function, impaired mobility, difficulty swallowing, and reduced ability to perform activities of daily living.
Aspiration Pneumonia and Respiratory Infections
One of the most serious complications of dementia is aspiration pneumonia, which occurs when food, saliva, or stomach contents enter the lungs. Progressive neurological decline often leads to dysphagia (swallowing difficulty), increasing the likelihood of aspiration. Dysphagia can also contribute to dehydration, malnutrition, and respiratory infections. In advanced dementia, aspiration pneumonia is a leading cause of hospitalization and death, highlighting the importance of monitoring swallowing function and respiratory health.
Malnutrition and Weight Loss
Malnutrition is highly prevalent among people living with dementia. Cognitive impairment can reduce appetite, disrupt eating behaviors, and impair the ability to recognize hunger or properly use utensils. In addition, dysphagia and behavioral symptoms such as agitation may further interfere with adequate nutritional intake. Studies have shown that poor nutritional status in dementia is associated with worse functional decline, increased morbidity, and higher mortality risk.
Falls and Functional Decline
As dementia progresses, individuals often experience impaired balance, reduced coordination, and decreased judgment, which substantially increases the risk of falls. Falls can lead to fractures, head injuries, and loss of independence. Functional decline in activities of daily living — including bathing, dressing, and mobility — further contributes to physical frailty and increased healthcare utilization.
Delirium and Neuropsychiatric Complications
People with dementia are particularly vulnerable to delirium, an acute state of confusion often triggered by infections, medications, or hospitalization. Delirium can accelerate cognitive decline, prolong hospital stays, and increase the risk of long-term functional deterioration. Neuropsychiatric symptoms such as agitation, hallucinations, and depression are also common complications that significantly impact quality of life and caregiver burden.
Pressure Injuries and Immobility
Advanced dementia frequently leads to decreased mobility and prolonged bed rest. Reduced movement increases the risk of pressure injuries (bedsores), muscle wasting, and deep vein thrombosis. These complications can worsen overall health status and increase the need for long-term care or institutionalization.
Increased Mortality
The Takeaway
Dementia is cognitive impairment that significantly affects your daily life, and can be caused by several different patterns or processes in your brain. While dementia can’t be cured, it can be treated or managed through medications, changes in your home and daily routine, and a healthy lifestyle with social connections. Don’t hesitate to seek cognitive screening if you notice any concerning changes in thinking or behavior.
FAQ
- What Is Dementia? Symptoms, Types, and Diagnosis. National Institute on Aging. December 8, 2022.
- Mild Cognitive Impairment (MCI). Alzheimer’s Association.
- Stages of Alzheimer's. Alzheimer’s Association.
- Vascular Cognitive Impairment and Vascular Dementia. Mayo Clinic. September 18, 2025.
- Lewy Body Dementia: Causes, Symptoms, and Diagnosis. National Institute on Aging. January 27, 2025.
- Frontotemporal Disorders: Causes, Symptoms, and Diagnosis. National Institute on Aging. January 22, 2025.
- Primary Progressive Aphasia. Mayo Clinic. February 7, 2025.
- Who Gets Frontotemporal Dementia? Alzheimer’s Society.
- Frontotemporal Dementia. Mayo Clinic. December 23, 2025.
- Alzheimer's Disease Facts and Figures. Alzheimer’s Association. 2025.
- Dementia: Diagnosis and Treatment. Mayo Clinic. June 7, 2025.
- Navigating Treatment Options. Alzheimer’s Association.
- Espay AJ et al. Lecanemab and Donanemab as Therapies for Alzheimer's Disease: An Illustrated Perspective on the Data. eNeuro. June 28, 2024.
- What Are the Treatment Options for Lewy Body Dementia? Lewy Body Dementia Association.
- Why Participate in a Clinical Trial? Alzheimer’s Association.
- Sommerlad A et al. Social Participation and Risk of Developing Dementia. Nature Aging. May 18, 2023.
- Budson AE. Sleep Well — and Reduce Your Risk of Dementia and Death. Harvard Health Publishing. May 3, 2021.
- The Later Stage of Dementia. Alzheimer’s Society.
- Dementia: Symptoms and Causes. Mayo Clinic. June 7, 2025.

David Weisman, MD
Medical Reviewer
David Weisman, MD, is the director of the Clinical Trial Center at Abington Neurological Associates in Pennsylvania, where he has conducted numerous clinical trials into mild cogni...

Pamela Kaufman
Author
Pamela Kaufman assigns and edits stories about infectious diseases and general health topics and strategizes on news coverage. She began her journalism career as a junior editor on...