12 Cancer Terms and Phrases to Know Before Starting Treatment

12 Cancer Terms to Know Before You Start Treatment

12 Cancer Terms to Know Before You Start Treatment
Everyday Health

Being diagnosed with cancer is overwhelming enough. But soon after you get the news, you may also be inundated with new and complex terms and concepts that describe the cancer and your potential care or treatment.

“I think hearing you have cancer, for most people, it’s like they’ve gotten run over by a truck,” says Alan Bryce, MD, chief clinical officer, a medical oncologist, and a professor of molecular medicine at the City of Hope Cancer Center and Translational Genomics Research Institute in Phoenix. “There’s just a lot of shock and awe. It’s hard to absorb.” So it’s understandable that any additional information, such as cancer terms, can feel like information overload.

It’s okay if you’re not able to wrap your head around the diagnosis yet, let alone all the terminology your medical team throws your way. “I tell people, ‘You’re not going to remember all this, and we’re gonna have to go over a lot of this again when I see you the next time,” says Dr. Bryce.

Your care team can walk you through the parts that feel complicated, and you’ll become more familiar with the words as time goes on. But if you want to start learning cancer terminology sooner, rather than later, here are some basic words for starters:

Cancer Terms to Know

1. Stage 

The first thing your doctor will likely tell you is the specific type of cancer you have, says Bryce, followed by the stage.

“The stage of cancer describes the extent of cancer, guides treatment choice, and can potentially indicate if the cancer is curable or not,” says Shanthi Sivendran, MD, senior vice president for cancer care support at the American Cancer Society and a hematology/oncology physician at Penn Medicine in Lancaster, Pennsylvania.

It’s important to know that the stage is defined differently across cancer types. Your doctor can provide information about what it means for you.

2. Grade

A tumor may receive a grade, based on how its cells appear under a microscope. As with stages, the grading system varies by cancer type. In general, a low grade means the cells are likely to spread or grow slowly. High-grade cells are expected to spread or grow faster.

3. Locally Advanced

Your oncologist may use this phrase to describe cancer that has spread to lymph nodes near the original tumor.

Whether the cancer has spread can affect which treatments your team recommends.

4. Metastasis

Metastasis is when cancer cells have spread from one part of the body to another, usually through the bloodstream or lymphatic system.

If this has happened with the cancer you have, your team may describe it as “metastatic,” which means it has spread farther than locally advanced cancer.

5. Standard of Care

You may hear your doctor mention that a certain treatment is the standard of care. That means it’s generally accepted to be the proper treatment for this particular disease at this time. You might also hear this called “best practice” or “standard therapy.”

6. Chemotherapy

Dr. Sivendran says that it’s important to understand early on what treatments are available to you and which specific types your doctor recommends.

Chemotherapy is a type of medication or combination of medications given to kill cancer cells. It’s often called “chemo” for short. The medication may be taken by mouth, injection, or infusion.

 

7. Radiation Therapy

In radiation therapy, high-energy rays or particles are used to shrink, kill, or damage cancer cells.

 External beam radiation therapy uses a machine to target a specific area with radiation, whereas internal radiation therapy puts a solid or liquid radiation source inside the body via a catheter, ingestion, or IV.

8. Immunotherapy

There are several types of immunotherapy. They all change the immune system to help the body fight cancer, disease, and infection.

 Immunotherapy trains your body’s immune cells to identify and destroy cancer cells, as well as produce more cells to do this. Common types of immunotherapy drugs include cancer vaccines, CAR T-cell therapy, checkpoint inhibitors, immune system modulators, and monoclonal antibodies.

9. Hormone Therapy

For some types of cancer, you may take medication to change hormones in your body to slow or stop cancer growth.

10. Adjuvant Therapy

“Adjuvant” is used to describe a treatment that complements or helps a main treatment. For example, a doctor could recommend surgery to remove a tumor, followed by hormone therapy as an adjuvant to kill any cancer cells that may remain.

Sivendran explains that treatments may be done in conjunction with each other. She says it’s important to know what order you’ll be getting them in and what side effects are common.

11. Biomarker Testing

Your care team could order tests to learn more about the cancer you have. Biomarker testing looks at genes or substances in the body that offer information about whether a cancer is likely to spread, treatment is working, or the cancer might return.

Biomarker testing may involve biopsies, blood tests, or saliva or skin samples.

12. Palliative Care

Palliative care or treatment (also known as supportive care or treatment) helps people with cancer cope with symptoms of the illness and the side effects of treatment. This type of care can improve quality of life by making you more comfortable and providing services to help with diet, energy, mental health, pain, and more. It’s available at any time during the cancer journey.

How to Gain a Better Understanding of Cancer Terminology

While these terms can get you started, there are many more concepts that will likely come up. Sivendran emphasizes that it’s important to ask your care team any questions you have to help understand the cancer type and suggested treatment course. You may also find it helpful to:
  • Jot down your questions ahead of your appointment, so you remember to ask all of them.
  • Take notes during appointments.
  • Ask your doctor to provide an after-visit summary that contains the diagnosis (including the stage and grade), the recommended treatment course, and any other important details.
  • Let your healthcare provider know if there are terms or concepts you’re still unclear on, so they can further explain or point you to another resource.

It’s also a good idea, Bryce says, to bring a family member or friend along to appointments to support you and also ask questions. “It helps to have more ears hearing the information,” says Bryce. “We understand that it’s overwhelming. It does take a while. We don’t expect you to get it all at once.”

The Takeaway

  • Getting diagnosed with cancer can be overwhelming, and understanding cancer terminology right away can be difficult.
  • The most important things to know about are the type and stage of the cancer and the treatments your doctor is recommending.
  • To help understand your treatment options, ask lots of questions in your appointments, bring a family member or friend to support you, and take notes.
EDITORIAL SOURCES
Everyday Health follows strict sourcing guidelines to ensure the accuracy of its content, outlined in our editorial policy. We use only trustworthy sources, including peer-reviewed studies, board-certified medical experts, patients with lived experience, and information from top institutions.
Resources
  1. Grade. National Cancer Institute.
  2. Adams M. Cancer Glossary: 13 Terms to Know About Your Diagnosis. University of Texas MD Anderson Cancer Center. January 31, 2022.
  3. Cancer Glossary: Definitions & Phonetic Pronunciations. American Cancer Society.
  4. Standard of Care. National Cancer Institute.
  5. What Is Chemotherapy? University of Michigan Health.
  6. Radiation Therapy to Treat Cancer. National Cancer Institute. May 15, 2025.
  7. Immunotherapy. National Cancer Institute.
  8. Immunotherapy. Cleveland Clinic. August 12, 2025.
  9. Hormone Therapy. National Cancer Institute.
  10. Biomarker Testing for Cancer Treatment. National Cancer Institute. December 14, 2021.
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Walter Tsang, MD

Medical Reviewer
Walter Tsang, MD, is a board-certified medical oncologist, hematologist, and lifestyle medicine specialist. Inspired by the ancient Eastern philosophy of yang sheng ("nourishing li...
Elena Donovan Mauer

Elena Donovan Mauer

Author

Elena Donovan Mauer is a writer, editor, and content strategist specializing in health and wellness. Her work has appeared in a variety of publications, including Healthline, Paren...