How Pumpkin Is a Cancer-Fighting Superfood — Plus, 3 Pumpkin Recipes

How Pumpkin Is a Cancer-Fighting Superfood — and 3 Recipes to Get You Started

How Pumpkin Is a Cancer-Fighting Superfood — and 3 Recipes to Get You Started
Everyday Health

Pumpkin is a staple of autumn treats, found in everything from pies to muffins to breads. But on its own, this squash is packed with healthy nutrients that may protect against cancer.

Pumpkins are rich in cancer-fighting antioxidants as well as fiber in the form of pectin; the seeds contain polyunsaturated fatty acids, which have been likewise shown to help prevent cancer.

No one food can ward off cancer, says Shaye Arluk, RDN, the nutrition and wellness coordinator at Sentara Brock Cancer Center in Norfolk, Virginia, but an overall healthy diet is certainly a good start. This fall, consider swapping pumpkin muffins for pumpkin chili — you just might find that the squash is more versatile (and healthier) than you thought.

How Pumpkin May Reduce Cancer Risk

Pumpkins — which are, botanically speaking, a fruit — contain natural plant compounds that have slowed cancer-cell growth in laboratory and animal studies, says Arluk.

Cell-Protecting Nutrients

Pumpkins get their bright orange color from their high concentration of beta-carotene, “a plant compound that converts into vitamin A in our bodies,” says Crystal Tallman, RD, who specializes in oncology nutrition at Mission Cancer + Blood, part of the University of Iowa in Des Moines. Vitamin A — as well as vitamins C and E, also found in pumpkins — acts as a powerful antioxidant, says Tallman.

Antioxidants can help fight free radicals, which are harmful molecules in the body that may contribute to cancer.

Fiber for a Healthy Gut

“Pumpkin is also an excellent source of fiber,” says Tallman. One cup of pumpkin has more than 5 grams (g) of fiber — more than that found in the same amount of strawberries, apples, or oranges.

 Fiber is also found in the pumpkin's edible skin, says Arluk.
Fiber can protect against cancer because it:

  • Bulks up stools: Fiber adds bulk to stools, speeding up their passage through the intestines. This can improve our metabolic health, protecting against certain cancers.

  • Balances hormones: Fiber helps your body use insulin more effectively, which prevents cancer-promoting inflammation.

     It also decreases estrogen, a hormone that can increase your risk for breast cancer.

  • Helps with weight management: Eating more fiber can help keep you at a healthy weight, which is one way to prevent cancer, says Arluk.

  • Balances gut bacteria: Fiber helps your body maintain a healthy microbiome — the community of bacteria and other microorganisms in your digestive system. A healthy gut microbiome may, in turn, help protect against colorectal cancer.

How Much Pumpkin Should You Eat?

In general, adults should eat about two servings of fruit each day.

“A serving of pumpkin is ½ cup canned or mashed or about one cup of pumpkin cooked and cubed,” says Anna Maria Merz, RD, an outpatient oncology dietitian at the Ohio State University Comprehensive Cancer Center Arthur G. James Cancer Hospital and Richard J. Solove Research Institute in Columbus.

Pumpkin Seeds vs. Pumpkin Flesh

Every part of a pumpkin fruit is edible — and, as it turns out, nutritious.

 “The nutritional benefits of pumpkin extend beyond the orange flesh,” says Tallman.
“Pumpkin seeds are high in protein, fiber, heart-healthy fats, and important minerals such as magnesium, zinc, and iron,” says Tallman.

 One-fourth cup of pumpkin seeds give you about 9 g of protein and almost half the daily recommended intake of magnesium.

"Pumpkin seeds also contain phytosterols, which are natural compounds in plants that may help lower cholesterol levels," says Merz.

The nutrients in pumpkin seeds can:

  • Strengthen your immune system
  • Reduce inflammation
  • Protect against free radicals
Because of these effects, experts think pumpkin seeds could lower your risk for several cancers, including breast, rectal, and lung cancers.

Pumpkin peels and leaves — two parts of the plant that are often overlooked — are also packed with nutrients. “The pumpkin peel contains a rich source of beta-carotene, polyphenols, potassium, and fiber,” says Arluk. “Pumpkin leaves are also used globally because they contain higher levels of antioxidants, minerals, and iron than our standard greens like spinach, kale, and broccoli.”

Fresh vs. Canned Pumpkin

Canned pumpkin can be as healthy as fresh pumpkin, says Merz. Canning pulls out the water content and creates a denser product per serving, so you usually get double the fiber and more iron from canned pumpkin than from the same amount fresh, says Arluk.

“When buying canned pumpkin puree, look for '100 percent pure pumpkin' on the label or check that 'pumpkin' is the only ingredient on the ingredient list,” says Merz.

Just make sure you choose unsweetened canned pumpkin. “Avoid pumpkin pie filling or pumpkin pie mix, which often contain added sugars and syrups that increase calories without adding nutritional value,” says Tallman.

“If you opt to use fresh — rather than canned — pumpkin in your food preparation, choose baking pumpkins, also called sugar pumpkins or pie pumpkins, instead of large carving pumpkins,” says Tallman. Baking pumpkins have more sugar and less moisture, which makes them a better option for purees, pies, soups, and breads than carving pumpkins.

1
pumpkin
Adobe Stock

Roasted Pumpkin Halves

This is perhaps the easiest way to cook and enjoy fresh pumpkin at home. In fact, one might say that it’s as easy as pie. If you’re going to blend or puree the cooked pumpkin for a soup or pie, this is the way to do it.

3.5 out of 2 reviews

SERVES

8

CALORIES PER SERVING

57

PREP TIME

5 min

COOK TIME

35 min

TOTAL TIME

40 min

Ingredients

1 whole sugar pumpkin
1 tsp olive oil

Directions

1

Preheat oven to 400 degrees F. Line a baking sheet with parchment paper and set aside.

2

Slice pumpkin in half and remove all seeds and strings. Reserve seeds for roasting.

3

Lightly brush flesh of pumpkin with olive oil and place it cut-side down on lined baking sheet.

4

Carefully pierce skin of each pumpkin half with a knife in a few places.

5

Place baking sheet in preheated oven and bake until pumpkin can be easily pierced with a fork, about 35–45 minutes.

6

Allow pumpkin to cool thoroughly before handling.

Nutrition Facts

Amount per serving

Serving sizeAbout 1 cup puree

calories

57

total fat

1g

saturated fat

0.2g

protein

2g

carbohydrates

13g

fiber

1g

sugar

5g

added sugar

0g

sodium

2mg

TAGS:

Anti-Inflammatory, Low-Fat, Heart-Healthy, Gluten-free, Low-Sodium, Vegetarian, Vegan
2
Mushroom Chili
Getty Images

Veggie-Packed Pumpkin Chili

With 10 grams (g) of fiber per serving, this veggie-stuffed chili really packs a nutritional punch. Plus, the smooth, pumpkin-enhanced broth is more than just nutritious, it adds a number of important nutrients to this dish as well. For example, ½ cup of pumpkin puree contains more than the recommended daily amount of vitamin A, according to the USDA and NIH.

5.0 out of 2 reviews

SERVES

6

CALORIES PER SERVING

217

PREP TIME

10 min

COOK TIME

27 min

TOTAL TIME

37 min

Ingredients

2 tbsp extra-virgin olive oil
1 medium yellow onion, chopped
1 cup baby portobello mushrooms, quartered
1 medium sweet potato, peeled and cubed
3 cloves garlic, minced
½ tsp ground cinnamon
2½ tsp ground cumin
2 tsp chili powder
1 tsp onion powder
½ tsp kosher salt
½ tsp freshly ground black pepper
1 15-oz can kidney beans, drained and rinsed
1 medium zucchini, chopped
1 cup frozen corn
1 15-oz can no-salt-added diced tomatoes, with juice
2 cups low-sodium vegetable broth
1 15-oz can pumpkin puree

Directions

1

Place a large pot over medium heat. Add olive oil, onion, mushrooms, and sweet potato. Cook, stirring frequently, until the onion softens, about 5 minutes. Add garlic and cook until it becomes fragrant, about 1 minute more.

2

Add cinnamon, cumin, chili powder, onion powder, salt, and pepper and cook for 1 minute.

3

Add remaining ingredients, reduce heat, cover, and simmer for 20 minutes, stirring occasionally. Serve and enjoy.

Nutrition Facts

Amount per serving

Serving size2 cups

calories

217

total fat

5.8g

saturated fat

1g

protein

9g

carbohydrates

35g

fiber

10g

sugar

7.3g

added sugar

0.3g

sodium

326mg

TAGS:

Cholesterol-Conscious, Dinner, Gluten-free, Mediterranean, High-Fiber, Vegan, Vegetarian
3
pumpkin soup
Svetlana Monyakova/iStock

Curried Pumpkin Soup

Nothing combines the flavors and feelings of autumn quite like pumpkin soup. Here, the rich flavor of curry brings this soup to life while lending the anti-inflammatory benefits of the spices it contains (namely turmeric, as Johns Hopkins Medicine notes). A touch of black pepper is added to increase your body’s ability to absorb the curcumin from the turmeric, as described in the results of a past study. Low-sodium broth makes this recipe healthier for your ticker.

4.1 out of 15 reviews

SERVES

6

CALORIES PER SERVING

165

PREP TIME

15 min

COOK TIME

25 min

TOTAL TIME

40 min

Ingredients

2 tbsp olive oil
1 large sweet onion, diced
2 cloves garlic, minced
2 medium apples, peeled and diced
1 medium sugar pumpkin (about 4 to 5 lb), roasted as above
4 cups low-sodium vegetable or chicken broth (plus more as needed)
1 tbsp ground curry powder (plus more to taste)
½ tsp ground nutmeg
1 tsp ground cumin
1½ tsp kosher salt, plus more to taste
½ tsp freshly ground black pepper
½ cup whole milk (optional)

Directions

1

Place a large stockpot over medium heat. Add olive oil and onion and sauté until onions begin to soften, about 5 minutes.

2

Add garlic and apple to stockpot. Sauté, stirring occasionally, until ingredients are soft, about 5 to 10 more minutes.

3

Add pumpkin and broth and bring mixture to a boil, then reduce to a simmer. Cover and continue to simmer for 15 minutes.

4

Remove pot from heat. Blend using an immersion blender or cool slightly and use a countertop blender.

5

Return to stove and season with curry powder, nutmeg, cumin, salt, and pepper. Stir in milk, if using, and serve.

Nutrition Facts

Amount per serving

Serving size1⅔ cup

calories

165

total fat

5g

saturated fat

0.8g

protein

3g

carbohydrates

31g

fiber

4g

sugar

17g

added sugar

1g

sodium

369mg

TAGS:

Gluten-free, Vegetarian, Vegan, Side Dish

Resources We Trust

EDITORIAL SOURCES
Everyday Health follows strict sourcing guidelines to ensure the accuracy of its content, outlined in our editorial policy. We use only trustworthy sources, including peer-reviewed studies, board-certified medical experts, patients with lived experience, and information from top institutions.
Resources
  1. Gavril Rațu RN et al. Pumpkin and Pumpkin By-Products: A Comprehensive Overview of Phytochemicals, Extraction, Health Benefits, and Food Applications. Foods. August 26, 2024.
  2. Pinna N et al. Carotenoids from Different Pumpkin Varieties Exert a Cytotoxic Effect on Human Neuroblastoma SH-SY5Y Cells. Nutrients. September 9, 2024.
  3. Squash, Pie Pumpkin, Peeled, Seeded, Raw. U.S. Department of Agriculture. April 24, 2025.
  4. Chart of High-Fiber Foods. Mayo Clinic. December 24, 2025.
  5. Hu J et al. Use of Dietary Fibers in Reducing the Risk of Several Cancer Types: An Umbrella Review. Nutrients. May 30, 2023.
  6. Celiberto F et al. Fibres and Colorectal Cancer: Clinical and Molecular Evidence. International Journal of Molecular Sciences. August 31, 2023.
  7. Cancer Prevention Overview (PDQ®)–Health Professional Version. National Cancer Institute. February 12, 2025.
  8. Farvid MS. Fiber Consumption and Breast Cancer Incidence: A Systematic Review and Meta-Analysis of Prospective Studies. Cancer. April 6, 2020.
  9. Fu J et al. Dietary Fiber Intake and Gut Microbiota in Human Health. Microorganisms. December 18, 2022.
  10. Kandalai S et al. The Human Microbiome and Cancer: A Diagnostic and Therapeutic Perspective. Cancer Biology & Therapy. July 27, 2023.
  11. Dietary Guidelines For Americans, 2025–2030. U.S. Department of Agriculture. 2025.
  12. Kassa MG et al. Phytochemical Composition, Health Benefits, Functional Properties, and Food Applications of Pumpkin Seeds. Food Science & Nutrition. May 8, 2026.
  13. Seeds, Pumpkin Seeds (Pepitas), Raw. U.S. Department of Agriculture. April 20, 2023.
  14. Peng M et al. Effect of Roasting on the Antioxidant Activity, Phenolic Composition, and Nutritional Quality of Pumpkin (Cucurbita pepo L.) Seeds. Frontiers in Nutrition. March 10, 2021.
  15. Raza N et al. Nutritional and Health Potential of Edible Seeds: Micronutrient Bioavailability and Mechanistic Insights. Food Science & Nutrition. January 28, 2026.
  16. Batool M et al. Nutritional Value, Phytochemical Potential, and Therapeutic Benefits of Pumpkin (Cucurbita sp.). Plants. May 24, 2022.
Jennifer Frediani

Jennifer Frediani, PhD, RD

Medical Reviewer

Jennifer K. Frediani, PhD, RD, ACSM-CES, is a nutrition scientist, exercise physiologist, and registered dietitian with over two decades of experience in clinical research, educati...

Abby McCoy, RN

Author

Abby McCoy is an experienced registered nurse who has worked with adults and pediatric patients encompassing trauma, orthopedics, home care, transplant, and case management. She is...