Top Supplements for Women: 7 to Consider for Better Health

Note: The U.S. Food and Drug Administration (FDA) does not approve supplements for safety or effectiveness. Talk to a healthcare professional about whether a supplement is the right fit for your individual health, and about any potential drug interactions or safety concerns.
“If you are unsure if a supplement you see on TikTok or your favorite celebrity is selling is worth it [or safe for you], ask your healthcare provider,” says Jennifer Lincoln, MD, a board-certified ob-gyn at Providence Health & Services in Portland, Oregon. “They can help you separate the fact from the fiction, and potentially save you quite a bit of money.”
Here are seven supplements for women to consider taking daily.
1. Vitamin D
2. Calcium
“Calcium and vitamin D are essential together for building and maintaining strong bones, especially as bone weakens naturally with age,” says Jennifer Choe, MD, an ob-gyn at Montefiore Einstein Advanced Care in New York City.
3. Iron
4. Folic Acid
“The critical window is often before women know they're pregnant, which is why women of reproductive age who could become pregnant should take a folic acid supplement,” Lincoln says. “You can't feel if you're getting enough folic acid.”
5. Vitamin B12
Vitamin B12 supports a healthy nervous system, red blood cell formation, and DNA synthesis. Levels tend to temporarily drop during pregnancy for several reasons, including that the mother’s blood becomes more diluted, the fetus requires more nutrients from the mother, and there’s greater loss of vitamin B12 in the mother’s urine. Vitamin B12 is particularly important in pregnant and breastfeeding women because deficiencies can cause issues like neural tube defects, developmental delays, and anemia in their children.
The risk of B12 deficiency is higher in those who don’t eat meat. It can cause symptoms like fatigue, a swollen tongue, heart palpitations, and low counts of red and white blood cells.
“B12 is found almost exclusively in animal products,” Lincoln says. “Plant-based diets don't provide reliable B12, and deficiency is extremely common among vegetarians and vegans who don't supplement.”
The body stores large amounts of B12, and it can take a long time to use up those reserves, so signs of B12 deficiency may take years to appear. Severe deficiency that causes clear blood or nerve issues is rare, but low or borderline B12 deficiency that is symptom-free may affect up to 40 percent of people in Western countries.
Before taking vitamin B12 supplements, speak to your doctor about potential medication interactions. Some drugs, like gastric acid inhibitors for issues like gastroesophageal reflux disease (GERD) or metformin for issues related to diabetes, can affect absorption. It’s best to take vitamin B12 in the morning with a glass of water for absorption and to avoid sleep disruptions.
Adult women generally need 2.4 mcg of vitamin B12, or 2.6 mcg during pregnancy and 2.8 mcg while breastfeeding.
6. Magnesium
Magnesium is a nutrient that supports many important body processes, including helping to increase bone mineral density in older women (though it isn’t clear if magnesium supplements help reduce the risk of osteoporosis).
Magnesium may also support sleep by helping muscles relax, and supplements might be helpful for perimenopausal and menopausal women, many of whom have sleep issues, says Maria Sophocles, MD, an ob-gyn who has a private practice in New York City.
Sleep issues during this stage of life may stem from fluctuations in the hormones estrogen and progesterone. Some experts recommend taking magnesium at bedtime to support sleep.
Magnesium is found in foods like leafy greens, beans, seeds, nuts, lean proteins, whole grains, and dairy. You may not need supplements if you eat these foods as part of a healthy diet. Typically, getting magnesium from food is considered safe because it’s digested less rapidly and excreted by the kidneys, whereas high-dose magnesium supplements can cause diarrhea, nausea, and cramping in certain individuals.
Magnesium deficiency can be asymptomatic, but mild cases often cause tremors, muscle spasms, numbness, and fatigue. Severe deficiency can lead to seizures, delirium, or heart arrhythmias. To confirm a diagnosis, your doctor can order a blood test.
Adult women generally need 310 to 320 mg of magnesium daily, or 350 to 360 mg if they’re pregnant and 310 to 320 mg if they’re breastfeeding.
7. Protein
Protein is important because it can help support lean muscle mass, Dr. Sophocles says. Changes in hormones during menopause may lead to muscle loss in women.
Most adults need 0.8 to 1.6 grams (g) of protein per kilogram (kg), or 2.2 pounds (lb), of body weight. Older adults need 1.2 to 1.6 g per kilogram to help preserve muscle mass, and experts recommend that physically active adults consume up to 2 g of protein per kilogram of body weight to support muscle repair and recovery.
To estimate your daily protein needs, divide your weight in pounds by 2.2 to convert it to kilograms, then multiply by this protein range. For example, a 150-lb person needs between about 55 and 136 g of protein per day, depending on their age, activity level, and other health goals. Your doctor can help you determine the right amount for you.
Research from Pakistan suggested that women with age-related muscle loss (sarcopenia) see significant improvements in muscle composition and strength when on a moderately high-protein diet (1.2 g per kg, or 2.2 lbs, of body weight per day) compared with a normal-protein diet (0.8 g per kg, or 2.2 lbs, of body weight per day).
Most people can get enough protein from their diet. However, supplementation may be helpful for those having trouble meeting their daily needs, such as cancer patients undergoing treatment, those recovering from surgery or severe injury, chronically ill patients, athletes, and those who don’t have the appetite to eat enough protein.
If you don’t like the chalky taste of protein powder, try adding it to your smoothies, soups, or pancake batter, Sophocles says.
The best way to know if you’re getting enough protein is to monitor your diet. Your doctor may also order a blood test, particularly if you have signs of extremely low protein levels, such as brittle hair and nails, fatigue, getting sick often, or muscle weakness.
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8 Foods High in Vitamin B12
5. Vitamin B12
6. Magnesium
7. Protein
To estimate your daily protein needs, divide your weight in pounds by 2.2 to convert it to kilograms, then multiply by this protein range. For example, a 150-lb person needs between about 55 and 136 g of protein per day, depending on their age, activity level, and other health goals. Your doctor can help you determine the right amount for you.
If you don’t like the chalky taste of protein powder, try adding it to your smoothies, soups, or pancake batter, Sophocles says.
The Takeaway
- Most women don't need a robust lineup of supplements if they're eating a balanced diet; however, in some cases (like you're not getting enough from food or for certain life phases (like pregnancy or perimenopause), extra support may be needed.
- Women’s nutritional needs change as they age, with iron and folate becoming more important for reproductive health, for instance, and protein and calcium needs increasing during postmenopause. Check with your healthcare team to make sure your nutritional needs continue to be met.
- Always consult your doctor before you start a new supplement. They can check your blood levels and review your medications for potential interactions while taking into consideration your specific health needs.
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Justin Laube, MD
Medical Reviewer
Justin Laube, MD, is a dual board-certified integrative and internal medicine physician, retreat leader, and healing educator with over 15 years of experience caring for patients w...

Kelsey Kloss
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Kelsey Kloss is a health and wellness journalist with over a decade of experience. She started her career as an in-house editor for brands including Reader’s Digest, Elle Decor, Go...