What Is Vitamin C Serum, and How Does It Help Your Skin?

What Is Vitamin C Serum, and How Does It Help Your Skin?

What Is Vitamin C Serum, and How Does It Help Your Skin?
Adobe Stock; Everyday Health

You might reach for vitamin C when you feel a cold coming on, but did you know it can also help you achieve a glowing complexion? In recent years, vitamin C has become a holy grail product for anyone looking to maximize their skin health.

“Vitamin C is a hot topic, and it is buzzworthy, because it has so many preventive and maintenance benefits,” says Nazanin Saedi, MD, a board-certified dermatologist and a clinical associate professor at Thomas Jefferson University in Philadelphia.

Here, we dive into everything you need to know about vitamin C serums, including why to use one, how to apply it, and what to watch out for.

What Is the Purpose of Vitamin C Serum?

A vitamin C serum is a skin-care product packed with vitamin C. It has the consistency of a liquid or gel, which you can apply directly to your skin. You’ll find these serums wherever you normally purchase skin-care products — at department stores, beauty stores, some drugstores, and in your dermatologist’s or aesthetician’s office too. On the packaging, you’ll likely see words touting skin benefits like “firming,” “brightening,” and “collagen boosting.” These skin benefits are the reason so many people have started adding vitamin C serum to their daily routines.

“The benefit of vitamin C is it’s an antioxidant, so it helps prevent the forming of free radicals, which go on to break down collagen and elastin,” Dr. Saedi says. She explains that the result of incorporating vitamin C serum into your skin-care routine is glowing, youthful skin.

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Does Vitamin C Serum Actually Work, and How?

Nutritionally speaking, vitamin C is important for our bodies. It’s essential for growth and development, playing a role in forming and repairing body tissue, and it provides antioxidants that fight the free radicals that contribute to diseases like cancer, heart disease, and arthritis. All fruits and vegetables contain some vitamin C, but you’ll source the most from produce such as cantaloupes, oranges, broccoli, and spinach.

Vitamin C is naturally present in the skin, where it boosts collagen production and antioxidant levels. It may also protect the skin against damage from UV light rays (especially when used alongside vitamin E). Vitamin C also maintains the skin’s barrier, which keeps irritants out of your skin, and aids in water retention for proper skin hydration.

These benefits sound great, right? So, you might be thinking it’s a good idea to increase your vitamin C intake just through diet. And while eating fruits and vegetables is a great idea for overall health, you’ll likely need a topical boost to reap the skin-care benefits of vitamin C. That’s because the epidermis, the outermost layer of the skin, doesn’t have blood vessels to send nutrients to the skin cells, research notes.

However, you can apply vitamin C directly to your skin, and that’s where serums come in handy. “Vitamin C is best known for its ability to neutralize free radicals and improve aging skin,” says Joel Schlessinger, MD, a dermatologic surgeon in Omaha, Nebraska. “It can also improve collagen and elastin synthesis — which can improve the appearance of fine lines and wrinkles, help reduce inflammation, provide natural, mild exfoliation, and brighten skin.”

And there’s evidence to back these claims too. One study found that topical vitamin C increased collagen production among study participants in all age groups. The study participants noticed the effects after 40 days of treatment, and found they were even more pronounced at the 60-day mark.

Vitamin C serum can also help with hyperpigmentation. Research notes that vitamin C plays a role in reducing tyrosinase (a type of enzyme that supports melanin production). By blocking this enzyme, vitamin C may aid in minimizing dark spots. Additionally, vitamin C offers protection against the sun’s UV rays — a common cause of hyperpigmentation.

Who Should Use a Vitamin C Serum on Their Skin?

Vitamin C is an important ingredient that can support a variety of skin concerns, including dark spots, wrinkles, sun damage, acne, and premature aging.

Anyone who wants to improve their skin health, especially if they’re dealing with these types of skin concerns, may consider adding vitamin C serum to their skin-care routine. But it’s a good idea to use vitamin C as a preventative measure, even if you’re not experiencing any significant skin concerns. The best time to deal with the visible signs of aging is before they occur, Dr. Schlessinger says.

Saedi recommends vitamin C serums for people of all ages because virtually everyone is at risk of sun damage. With vitamin C serums, “we are minimizing the amount of sun damage that our skin’s getting from sunlight,” she says. She explains that vitamin C serum does double duty, both protecting the skin and helping problem areas recover. “It’s preventive in that it’s protecting you from sun damage and signs of aging like wrinkles,” Saedi says. “It also helps promote collagen and boost your natural collagen formation.”

Expert Tips for Choosing a High-Quality Vitamin C Serum

You’ll find vitamin C in a few different forms, including L-ascorbic acid, tetrahexyldecyl ascorbate, and magnesium ascorbyl phosphate.

 So, how exactly do you choose which to go with? Well, it depends on your exact skin concerns and goals, as well as your budget.

The price of these serums can vary greatly, from about $10 to $250 per ounce. Pay attention to the vitamin C concentration levels, usually referred to as L-ascorbic acid or ascorbic acid on the label. Schlessinger explains that some of these serums may have 10 percent, while others may have 15 or 20 percent.

Look for one with a concentration higher than 8 percent, which is the minimum amount considered biologically significant. The higher the concentration, the stronger the serum, though the benefits taper off after 20 percent. “Twenty percent is where it maxes out — you’re not going to get anything more powerful than that,” Saedi adds.

When choosing your product, look for one that also contains vitamin E, which helps deliver vitamin C more effectively.

“When vitamin C and E are combined, they work together to provide very powerful antioxidant protection,” Schlessinger says.
Ferulic acid is also a good addition to your skin-care routine — it helps stabilize vitamin C, which makes it less likely to irritate the skin and more effective.

“When these vitamins [C and E] work with ferulic acid, they enhance one another’s stability to ensure maximum benefits are achieved,” Schlessinger adds.

How to Use Vitamin C Serum Correctly

Saedi says to apply a few drops of serum to your face after you wash and dry it. “A little bit goes a really long way,” she says. She recommends putting it on every morning, all year round. “It has some benefits with sun exposure, so it helps to apply it in the morning as the first layer of protection,” she says. She says to then layer on your moisturizer and sunscreen. Serums are better than drops of vitamin C “boosters” added to your moisturizer, Saedi says. Vitamin C drops may not be as potent as serums, and mixing them with moisturizer may dilute the effects.

Store your bottle in an area away from extreme heat, such as a bathroom cabinet. “Storing a vitamin C serum correctly is integral to its success,” Schlessinger says. “A good rule of thumb is to toss the serum six months after it’s been opened and to keep the serum in a cool, dark place.” If you’re using it according to the instructions, it’ll likely be gone before the six months are up. If not, you’ll want to throw it out. “When vitamin C is used past its shelf life, it can actually have negative effects,” Schlessinger says.

Potential Side Effects and Risks of Vitamin C Serums

Vitamin C is a safe and generally well-tolerated ingredient. “The only risk is that some of these serums have so many different ingredients in them,” Saedi says, adding that these extra ingredients may result in an allergic reaction in some people.

However, in rare cases, you may experience some skin dryness, itching, or redness after using vitamin C serums. This is typically only a minor concern if you have sensitive skin. So, in order to help minimize these potential risks, consider starting with a lower concentration of L-ascorbic acid, such as the 10 percent one first, before jumping up to higher levels.

Dermatologist-Approved Vitamin C Serums to Buy

SkinCeuticals C E Ferulic With 15 Percent L-Ascorbic Acid ($166, Skinceuticals.com) is “tried and true,” says Saedi, who notes it has a cultlike following.

Drunk Elephant C-Firma Day Serum ($79, Sephora.com) contains 15 percent L-ascorbic acid, plus ferulic acid for a powerful yet lightweight day serum.

Paula’s Choice C15 Super Booster ($55, Dermstore.com) is another high-potency pick with 15 percent vitamin C, along with vitamin E and ferulic acid, plus hyaluronic acid to attract moisture for supple skin.

Vichy 16 Percent Pure Vitamin C Brightening Serum ($35, Ulta.com) boasts minimal ingredients to keep things simple. With ascorbic acid, vitamin E, and hyaluronic acid, this serum may boost skin smoothness and radiance.

The Takeaway

  • Many people have started using vitamin C serums due to their ability to boost skin health, minimize fine lines, and protect from sun damage.
  • Vitamin C can help improve collagen production, brighten your skin, and reduce dark spots or hyperpigmentation.
  • While vitamin C is generally very safe for everyone, if you have sensitive skin, consider using a lower concentration when you’re first starting out with a serum.

Additional reporting by Jessica Migala.

EDITORIAL SOURCES
Everyday Health follows strict sourcing guidelines to ensure the accuracy of its content, outlined in our editorial policy. We use only trustworthy sources, including peer-reviewed studies, board-certified medical experts, patients with lived experience, and information from top institutions.
Resources
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  3. Blood Supply to the Epidermis. LibreTexts Health. October 14, 2025.
  4. Crisan D et al. The Role of Vitamin C in Pushing Back the Boundaries of Skin Aging: An Ultrasonographic Approach. Clinical, Cosmetic and Investigational Dermatology. September 2, 2015.
  5. Sanadi RM et al. The Effect of Vitamin C on Melanin Pigmentation — a Systematic Review. Journal of Oral and Maxillofacial Pathology. September 9, 2020.
  6. Nathan N et al. Why Is Topical Vitamin C Important for Skin Health? Harvard Health Publishing. November 10, 2021.
  7. Lazar M et al. Consumer Preferences of Topical Vitamin C Products: A Comparative Study. Cureus. September 17, 2023.
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  9. Benefits of Ferulic Acid as Part of Your Skin Care Routine. Cleveland Clinic. June 7, 2024.
  10. What Can Vitamin C Do for Your Skin? Cleveland Clinic. December 12, 2022.
Jacquelyn Dosal

Jacquelyn Dosal, MD

Medical Reviewer

Jacquelyn Dosal, MD, is a board-certified dermatologist practicing at The Dermatology House in Park City, Utah. Her areas of expertise include acne, rosacea, integrative treatments of inflammatory skin diseases, as well as laser treatment of the skin and injectables.

Dr. Dosal writes cosmetic questions for the certifying exams for the American Board of Dermatology. She is also the deputy editor for the American Academy of Dermatology's podcast, Dialogues in Dermatology.

Moira Lawler

Author
Moira Lawler is a journalist who has spent more than a decade covering a range of health and lifestyle topics, including women's health, nutrition, fitness, mental health, and travel. She received a bachelor's degree from Northwestern University’s Medill School of Journalism and lives in the Chicago suburbs with her husband, two young children, and a giant brown labradoodle.