11 Best Vitamin C Serums of 2026

We Tested 19 Vitamin C Serums. Here Are Our Favorites for Gorgeous, Glowing Skin

If you’ve ever made a fruit salad, you know that squeezing a lemon on your apple and banana slices keeps them from turning brown. It’s largely the vitamin C in the lemon that keeps the fruit from oxidizing. Vitamin C offers the same protective benefits to your own skin.

“Vitamin C is wonderful,” says Angela Lamb, MD, a dermatologist and associate professor at the Icahn School of Medicine at Mount Sinai in New York City. “It’s good for targeting brown spots because it has antioxidant properties. It helps with pigmentation and brightening of tone.”

Like the lemon on the apple, vitamin C provides a protective shield that “neutralizes free radical damage from environmental factors that accelerate signs of skin aging, such as UV exposure and pollution,” says Helen He, MD, a dermatologist and the director of lasers and cosmetic surgery at Mount Sinai in New York City. This is why vitamin C is best applied in the morning — a large part of its benefit comes from shielding your skin from the onslaught of stressors you’re exposed to throughout the day.

Here at Everyday Health, we tested 19 leading vitamin C serums (and one cream) to put together a list of our 11 favorites. I had never used vitamin C consistently before this trial, and by the end of it, I was sold. My skin is luminous and glowing, and its tone is so even that I’ve stopped regularly using concealer. The dark circles I’ve always had under my eyes have almost disappeared. The power of vitamin C has been a revelation for me, and it’s one you can easily experience yourself.

We’ve included picks at different price points, suitable for various skin types, and catering to specific issues to help you select a vitamin C serum that brings out the best in your skin.

vitamin c serum

Best for Building a Strong Skin Barrier

SkinCeuticals Phloretin CF with Ferulic Acid

Pros

  • Fan favorite with a cult following
  • Dermatologist recommended
  • Ferulic acid boosts effectiveness

Cons

  • High price point

Key Specs

  • Type of vitamin C: L-ascorbic acid
  • Concentration: 10%
  • Additional ingredients: Phloretin (2%), ferulic acid (0.5%)
  • Size: 1 oz
SkinCeuticals’ Phloretin CF is a newer, yet similar, formula to its legendary CE Ferulic Serum, which has a well-deserved reputation as perhaps the best vitamin C serum on the market. Phloretin CF, which was introduced several years later, is recommended more for normal, oily, or combination skin, while the original CE Ferulic is better suited to dry skin. Both contain L-ascorbic acid (pure vitamin C) and ferulic acid, another antioxidant that can actually double the effectiveness of vitamin C when combined.

The main difference is that this formula contains 5 percent less vitamin C than the original CE Ferulic. Instead, it swaps in phloretin, another powerful antioxidant derived from plants (apples and pears, in this case).

Phloretin has many of the same visible anti-aging and brightening effects as vitamin C, as it has “antioxidant, anti-inflammatory, and anti-cancer properties,” according to research.

It’s so effective against cancer, it’s currently being studied for chemoprevention as well as chemotherapy, so if you spend a lot of time in the sun, this is an ideal serum to layer under your sunscreen. Not only will it help your skin look good, but it may also help protect you from skin cancer.

Of the five vitamin C serums I tried, this one had, by far, the most positive impact on my skin. I noticed increased luminosity and firmness, but the real shock was how much it improved my skin’s actual health. I was diagnosed with perioral dermatitis (POD) about three years ago. A prescription cream has kept flare-ups in check, but nothing has really helped heal it until I used this serum. The redness and flaking around my nose began to retreat immediately. After using this serum daily for about a month, my POD looks and feels better than it has in years.

vitamin c serum

Best for Dark Spots

Clinique Even Better Clinical Dark Spot Clearing Serum

Pros

  • Additional ingredients specifically target dark spots
  • Suitable for all skin types; safe for sensitive skin
  • Free from sulfates, parabens, fragrances

Cons

  • Concentration of vitamin C not disclosed
  • Tall, thin bottle is inconveniently shaped 

Key Specs

  • Types of vitamin C: Magnesium ascorbyl phosphate (MAP), ascorbyl glucoside
  • Concentration: Not disclosed
  • Additional ingredients: UP302 (Clinique’s proprietary brightening molecule), niacinamide, salicylic acid, glucosamine
  • Size: 1 oz (also available in 1.7 oz and 2.5 oz)

Vitamin C is scientifically proven to reduce dark spots. Here, Clinique has paired it with several other ingredients to reduce dark spots, creating an effective combination product.

The company doesn’t disclose the amount of vitamin C its formula contains, but the derivatives it uses — magnesium ascorbyl phosphate (MAP) and ascorbyl glucoside — are both less irritating than pure L-ascorbic acid. They’re also considered particularly effective in promoting collagen production. Unlike L-ascorbic acid, MAP and ascorbyl glucoside are water-soluble, so you don’t have to worry about reduced effectiveness if you apply the product right after washing your face.

This formula also contains UP302, a proprietary molecule developed by Clinique to mimic the botanical harebell (Dianella ensifolia). It’s another potent antioxidant known to brighten the skin.

Niacinamide, also known as vitamin B3, helps fade dark spots and strengthen the moisture barrier. Meanwhile, salicylic acid and glucosamine are chemical exfoliants that remove dead skin to reveal brighter, new skin on the surface.

 

Our tester, Everyday Health editor Nicole Bonaccorso, found this serum gave her a generally brighter complexion after just one week and left her skin feeling hydrated. She noted the product did not yield dramatic, quick results in terms of dark spots, but she appreciated that it felt gentle and liked it enough to continue using it long term.

Bonaccorso also enjoyed the feel of the serum, which she described as “more of a thin lotion, creamier than a serum. It isn’t sticky, but rather smooth and silky, and it absorbs well. It feels like you’re just adding an extra moisturizer, so it’s unintimidating,” she says.

vitamin c serum

Best for Acne-Prone Skin

Mad Hippie Vitamin C Serum

Pros

  • Ferulic acid boosts effectiveness
  • Pleasant scent
  • Feels good on skin
  • Good introductory serum
  • Specifically formulated to treat acne and acne blemishes 

Cons

  • Results are slow and subtle
  • Effects on fine lines and wrinkles are mild

Key Specs

  • Type of vitamin C: Sodium ascorbyl phosphate (SAP)
  • Concentration: Equivalent to 15–20% L-ascorbic acid
  • Additional ingredients: Vitamin E, ferulic acid, hyaluronic acid, chamomile, konjac root
  • Size: 1 oz
One of vitamin C’s bonus benefits is its ability to fight acne. It can dry out oily skin, ward off environmental stressors like pollution, reduce inflammation, and aid in healing scars and discoloration caused by breakouts.

As you might expect from the name, Mad Hippie’s C serum is packed with natural ingredients, including chamomile to reduce redness and soothe skin, and konjac root, which helps lock in moisture.

 

The form of vitamin C in this formula, sodium ascorbyl phosphate (SAP), is known to be particularly good at fighting acne. One study found a 5 percent SAP formula reduced acne by 48.8 percent after 8 weeks.

“I really liked mostly everything about this product,” says Bonaccorso, who tested this serum. “My skin felt good wearing this. It looked brighter, and the product feels good going on. It feels silky between the fingertips while applying, and I like that it has a faint scent. I like how it wears as well.”

Vitamin C serums can sometimes smell pretty bad and feel sticky, which can discourage people from using them. If you’re concerned about a nice-feeling application, this is a great formula to try. Also, the scent is not artificial. It comes straight from the real botanicals included in this serum. “We do not use synthetic fragrances in our line, however, this serum does contain konjac root, chamomile, and clary sage extracts which do impart a faint aroma,” Mad Hippie reports on its website.

Results with this one may be slow and subtle, but that’s often the case with skin care products.

vitamin c serum

Best for Sensitive Skin

Typology L32 Radiance Serum 11% Vitamin C + Silk Tree Extract

Pros

  • Relatively mild concentration is gentle for sensitive skin
  • Silk tree extract helps brighten skin
  • 99% naturally derived
  • Scent-free

Cons

  • Only one additional active ingredient
  • May dry out skin

Key Specs

  • Type of vitamin C: Sodium ascorbyl phosphate (SAP)
  • Concentration: 11%
  • Additional ingredients: Silk tree extract
  • Size: 1 oz

Typology is a brand designed for minimalists. Everything about its products, from the sparse ingredients list to the sleek packaging and the bottle’s sans serif typeface, has a “less is more” feel to it.

Its vitamin C serum contains a modest 11 percent concentration of SAP, a vitamin C derivative that is gentler and more stable than pure L-ascorbic acid. The only additional active ingredient is an extract from the bark of the Persian silk tree (Albizia julibrissin), which is also an antioxidant and anti-inflammatory that has been used for centuries in traditional Chinese medicine to treat mood disorders, insomnia, and skin infections. Now, it’s a common ingredient in skin care products, and its effect on skin is being studied more closely. One study found it to be an effective treatment for atopic dermatitis in cell and animal models, primarily due to its powerful anti-inflammatory properties.

Our tester, Ashley Rowe, appreciated that the product was truly odorless, as many supposedly “unscented” products can still smell pretty strong. “I have some dark spots and dark circles, and while I did not notice a change in those areas, I did notice an overall evening of my skin tone,” Rowe says.

To be fair, Rowe tested the product for two weeks, and most vitamin C serums, even those with higher concentrations, typically take at least four weeks to have a noticeable effect. Rowe did notice that if she used a light moisturizer, her skin felt pretty dry by the end of the day. She suggests using a heavier cream on top of this serum. “It is lightweight and smooth and absorbed into my skin within one to two minutes,” she says.

vitamin c serum

Best Drugstore Brand

e.l.f. Skin Bright Icon Vitamin C + E + Ferulic Serum

Pros

  • Ferulic acid enhances effects
  • Affordably priced
  • Effective
  • Cruelty-free

Cons

  • Slightly sticky
  • Not suitable for oily skin

Key Specs

  • Types of vitamin C: 3-O-ethyl ascorbic acid
  • Concentration: 15%
  • Additional ingredients: Ferulic acid, vitamin E
  • Size: 1 oz

Although it uses a different, less potent form of vitamin C, this serum’s basic breakdown (15 percent vitamin C, 0.5 percent ferulic acid, and 1 percent vitamin E) is comparable to some of the more expensive items out there. If you’re looking for an affordable dupe, we suggest this one.

Our tester, Everyday Health editor Katie Tuttle, described this serum as “thin and oily, and it absorbs quickly. I got positive results from using it consistently; my skin seemed brighter and more hydrated.” While her one-week trial wasn’t enough to see an impact on her dark spots, it did brighten her skin significantly, and she liked the product enough to continue using it.

vitamin c serum

Best Low Concentration

Innisfree Green Tea Enzyme Vitamin C Brightening Serum

Pros

  • Gentle on the skin
  • Quick results
  • Suitable for sensitive skin
  • Effective for very smooth skin

Cons

  • Vitamin C concentration may be lower than others

Key Specs

  • Types of vitamin C: 3-0-ethyl ascorbic acid, ascorbyl tetraisopalmitate
  • Concentration: Not disclosed
  • Additional ingredients: Green tea enzyme, hyaluronic acid, niacinamide, ferulic acid, vitamin E
  • Size: 1 oz
Innisfree is one of our favorite Korean beauty brands, and its Green Tea line is particularly popular. Innisfree’s green tea–derived enzyme is frankly the hero ingredient in this serum, while the vitamin C content plays more of a supporting role. The brand claims its green tea enzyme exfoliates the skin and has been proven to reduce wrinkles, promote collagen production, lighten skin, and even inhibit the growth of skin cancer cells.


Tuttle found she gained extremely smooth skin from using this product. Vitamin C needs to have at least an 8 percent concentration to have an effect on its own, but paired with the green tea enzyme, this serum brings quick results.

If you’re sensitive to vitamin C and looking for a serum that functions similarly in terms of brightening — and also gives you extremely smooth skin — we recommend giving this one a try. Like most Korean beauty products, the formula is also designed to keep your skin healthy: It includes niacinamide to help strengthen your moisture barrier and soothe skin that may be irritated by exfoliation due to other ingredients.

“The product absorbs well and has a texture that is somewhere between an oil and a gel. It took a little bit longer to absorb, but with a little patience, it played nicely with my moisturizer, sunscreen, and makeup regimen,” Tuttle says. “My skin felt smooth and hydrated; I was pleasantly surprised that I noticed a difference within a week.”

vitamin c serum

Best High Concentration

TruSkin Vitamin C Serum

Pros

  • Effective at brightening
  • Unscented
  • Lightweight feel on skin

Cons

  • May cause irritation due to high concentration of vitamin C

Key Specs

  • Type of vitamin C: Sodium ascorbyl phosphate (SAP)
  • Concentration: 20%
  • Additional ingredients: Hyaluronic acid, vitamin E, aloe
  • Size: 1 oz
Most vitamin C serums are formulated using a 10 to 20 percent concentration. At concentrations higher than 20 percent, research indicates that vitamin C is more likely to cause irritation, with no added benefit to the skin.

 TruSkin’s Vitamin C Serum pushes the envelope of this limit. I found it effective in both brightening my skin and fading my freckles, and it even plumped the skin around my eyes. After a few weeks using this product, my face looks like the skin care equivalent of a shiny new penny.

During my testing, I also tried a 22 percent concentration vitamin C serum as well, and, just as the research posits, my skin became irritated, with rough, red patches across my cheeks. TruSkin’s vitamin C serum, with just a slightly lower concentration, didn’t irritate my skin at all. It went on so smooth and clean, it felt like nothing at all, and offered visible brightening results in just weeks.

One caveat: While this is the highest concentration vitamin C serum on this list, that doesn’t necessarily mean it’s the most effective. I found that the SkinCeuticals Phloretin CF with Ferulic Acid yielded more noticeable results (albeit at 10 times the price), which goes to show that much of a serum’s efficacy depends on its individual formulation and blend of ingredients. In particular, whether the formula contains ferulic acid or not is going to play a big factor, making it hard to make cut-and-dry comparisons between concentrations.

This is not to say TruSkin’s formula lacks effectiveness; it contains hyaluronic acid to help hydrate and vitamin E and aloe to help soothe and protect skin. If you’re looking for a high-concentration serum that delivers dramatic results, TruSkin doesn’t disappoint.

vitamin c serum

Best for Redness

The Inkey List 15% Vitamin C + EGF Serum

Pros

  • Cruelty-free
  • Affordably priced
  • Effective
  • EGF peptide boosts elasticity
  • Unscented

Cons

  • Thin consistency can feel runny
  • May cause irritation

Key Specs

  • Type of vitamin C: Ascorbyl glucoside
  • Concentration: 15%
  • Additional ingredients: 1% Epitensive (epidermal growth factor)
  • Size: 1 oz

Similar to e.l.f.’s vitamin C serum, The Inkey List offers a reliable, well-loved, and effective vitamin C serum at a highly affordable price. During testing, Everyday Health writer Mary Sauer found The Inkey List’s formula was particularly good at evening out redness, leaving her skin looking brighter overall. She didn’t like how runny the serum was, but “on the plus side, it absorbed very quickly. It is a little oily, but that feel went away after it was fully absorbed,” she says of the application experience.

This formula contains 15 percent ascorbyl glucoside, a vitamin C derivative that is gentler, less irritating, and more stable than pure L-ascorbic acid, so the effects last longer.

It also includes 1 percent Epitensive, a patented compound that mimics epidermal growth factor (EGF), a protein found in the body that is key to healing wounds.

When used in skin care products, EGF stimulates cell renewal and boosts collagen production, so it targets wrinkles and fine lines, making this serum more well-rounded than vitamin C serums that focus exclusively on pigmentation and tone.

vitamin c serum

Best for Firm Skin

Youth to the People 15% Vitamin C + Caffeine Energy Serum

Pros

  • Full of natural plant extracts
  • 3 vitamin C derivatives provide well-rounded efficacy
  • Caffeine helps reduce puffiness
  • Cruelty-free

Cons

  • May not layer well under makeup

Key Specs

  • Types of vitamin C: 3-O-ethyl ascorbic acid, tetrahexyldecyl ascorbate (THD ascorbate), magnesium ascorbyl phosphate (MAP)
  • Concentration: 15%
  • Additional ingredients: Caffeine, passion fruit extract, dragon fruit extract, squalane
  • Size: 1 oz

The ingredients list may sound more like a snack than a serum, with dragon fruit, passion fruit, and caffeine derived from yerba mate and guayusa, but Youth to the People’s formula is highly effective.

Dragon fruit, passionfruit, and squalane join forces with three vitamin C derivatives to create a powerhouse force of antioxidants. While vitamin C helps firm skin by stimulating collagen production, it is the plant-sourced caffeine that takes the lead in tightening skin and reducing puffiness.

Like vitamin C, caffeine stimulates collagen production for long-term results. It has been shown to reduce wrinkles when used twice daily for 4 weeks.

 Caffeine also constricts blood vessels, which reduces blood flow to the skin and causes an immediate reduction in puffiness.

“I lost 40-plus pounds rapidly and have been trying to get some of the skin in my face to tighten. Since starting this, I am starting to see some difference in my jaw area. I also feel like this serum wakes up my skin, and it looks brighter after use,” Sauer says. She also enjoyed the application of this formula, which felt “very, very light and enjoyable.” Sauer also felt that the product would last a long time, as “a little bit goes a very long way.”

If you’re looking for a serum that does double duty with both brightening and firming properties, this is an excellent choice. “It was one of my favorite products I’ve tried recently. I really noticed a difference in looseness, skin tone, and puffiness in the morning,” Sauer says.

vitamin c serum

Best Cream

Laneige Radian-C Cream

Pros

  • Gentle
  • Pleasant scent
  • Highly moisturizing
  • Luxurious-feeling application

Cons

  • Low concentration may yield mild results

Key Specs

  • Type of vitamin C: 3-0-ethyl ascorbic acid
  • Concentration: 8.5%
  • Additional ingredients: Madecassoside (derived from Centella asiatica, also known as gotu kola), vitamin E
  • Size: 1 oz

This may be a list of vitamin C serums, but if you prefer a cream, we’ve got you covered: Laneige, a high-quality and well-loved Korean skin care company, delivers vitamin C with fantastic brightening, luxurious hydration, and an outstanding application experience in cream form. With a serum, you need to cover your application with a cream anyway; Laneige saves you the extra step.

“The scent, the bottle, the fact that it comes with a little orange applicator, the texture, the way it felt on my skin — I kind of loved everything about it,” says Everyday Health editorial director Simone Scully, who tested this product. “I’m a huge fan of Laneige products generally, but this one in particular is great.”

Scully particularly raved about the application feel of the cream. “It dissolves so well you forget it is there,” she says. Her three-week trial left her skin feeling softer and brighter. In a world where vitamin C can be sticky and stinky, the creamy texture and delicious citrusy scent of this cream earn it points for both application and results.

Laneige also includes some excellent additional ingredients into this cream: Vitamin E helps trap moisture and soften skin, while madecassoside from the Centella asiatica plant (one of my personal favorite botanical extracts) promotes cell regeneration and heals irritated skin.

vitamin c serum

Best for Dry Skin

NourishMax Vitamin C + B + E + Ferulic Serum

Pros

  • Ferulic acid boosts effectiveness
  • Goes on smooth; not sticky or tacky
  • Works on fine lines, discoloration
  • Very hydrating
  • Cruelty-free
  • Highly effective

Cons

  • Mildly unpleasant scent
  • Slightly oily feel

Key Specs

  • Type of vitamin C: L-ascorbic acid
  • Concentration: 15%
  • Additional ingredients: Vitamin E, ferulic acid, niacinamide (vitamin B), hyaluronic acid
  • Size: 1 oz

With a 15 percent concentration of pure vitamin C boosted by ferulic acid, it’s no wonder Bonaccorso found this product highly effective as well as highly moisturizing. “I think this brightens, hydrates, and addresses fine lines. It feels nourishing to the skin,” she says. “My skin looked brighter and more hydrated, and perhaps a bit smoother where my fine lines are around my eyes.”

According to Dr. Lamb, ferulic acid is one of the best additional ingredients a vitamin C serum can have. Not only is it an antioxidant in its own right, it also enhances the efficacy of the vitamin C while stabilizing it so it lasts longer and is less irritating on the skin.

This product also contains vitamin E, which has been shown to reduce pigmentation when combined with vitamin C and ferulic acid.

 Niacinamide and hyaluronic acid are in the mix to not only hydrate skin but also strengthen the skin barrier to keep that moisture locked in.

Superlative
Concentration
Type of Vitamin C
Additional Ingredients
Buy Now
Best for building a strong skin barrier
10%
L-ascorbic acid
Phloretin, ferulic acid
Best for dark spots
Not disclosed
Magnesium ascorbyl phosphate, ascorbyl glucoside
UP302, niacinamide, salicylic acid, glucosamine
Best for acne-prone skin
Equivalent to 15–20% L-ascorbic acid
Sodium ascorbyl phosphate
Vitamin E, ferulic acid, hyaluronic acid, chamomile, konjac root
Best for sensitive skin
11%
Sodium ascorbyl phosphate
Persian silk tree extract
Best drugstore brand
15%
3-O-ethyl ascorbic acid
Ferulic acid, vitamin E
Best low concentration 
Not disclosed
3-0-ethyl ascorbic acid, ascorbyl tetraisopalmitate
Green tea enzyme, hyaluronic acid, niacinamide, ferulic acid, vitamin E
Best high concentration
20%
Sodium ascorbyl phosphate
Hyaluronic acid, vitamin E, aloe
Best for redness
15%
Ascorbyl glucoside
1% Epitensive (epidermal growth factor)
Best for firm skin
15%
3-O-ethyl ascorbic acid, tetrahexyldecyl ascorbate, magnesium ascorbyl phosphate
Caffeine, passion fruit extract, dragon fruit extract, squalane
Best cream
8.5%
3-0-ethyl ascorbic acid
Madecassoside
Best for dry skin
15%
L-ascorbic acid
Vitamin E, ferulic acid, niacinamide, hyaluronic acid

Other Noteworthy Vitamin C Serums We Tried

We tested 19 vitamin C serums for this roundup. Although these didn’t quite make the cut, we still found them outstanding enough to recommend:

Maelove: The Glow Maker Antioxidant Serum

Maelove’s Glow Maker serum is one of Dr. He’s top choices in vitamin C serums. It’s got both ferulic acid and vitamin E as well as a powerful dose of 15 percent pure L-ascorbic acid. The catch is the odor. “It smells smoky. The scent reminded me of what hot dogs smell like right out of the package, and made continued use very difficult,” says Rowe, who tested this product.

Drunk Elephant C-Firma Fresh Day Serum

I was excited to try this serum, as it has a great reputation, and I generally love Drunk Elephant products. It didn’t disappoint in terms of results, either — it improved my skin tone, firmed my fine lines, and faded my freckles. For me, the issue was the metallic smell and the application feel. This serum is quite a bit thicker than any other I’ve tried, which makes it harder to evenly coat your whole face and causes the smell to linger. Covering the serum with lotion neutralized the stickiness, but it still felt heavy and greasy on my skin.

La Roche-Posay Vitamin C12 Serum

We love that La Roche-Posay’s 12 percent vitamin C serum comes in two formulations, one for normal and one for oily/combination skin. It’s also boosted with hyaluronic acid to moisturize and salicylic acid to exfoliate. “This was my favorite of the vitamin C serums I tested because I felt like I noticed the best results with it,” says Scully. However, she did notice the serum felt sticky on her face and fingers. We also took issue with the bottle: It contains pure vitamin C, which is unstable and degrades easily when exposed to sunlight, yet it comes packaged in a transparent, light orange bottle. It may look more appealing than muted dark brown or completely opaque bottles, which are the industry standard, but it will degrade more rapidly if stored on a counter exposed to sunlight.

How We Tested Vitamin C Serums

vitamin c serum testing
Everyday Health

After conducting extensive research, including interviews with two top dermatologists, Angela Lamb, MD, a dermatologist and associate professor at the Icahn School of Medicine at Mount Sinai in New York City, and Helen He, MD, a dermatologist and the director of lasers and cosmetic surgery at Mount Sinai in New York City, we chose 19 vitamin C serums to test over two months between six testers. I brought my own experience, including years of evaluating and writing about healthcare products and being picky about skin care, to the table.

We assessed effectiveness, considering how well the product worked and what it excelled at in particular. We also took into account the application process, including whether the container was easy to use, whether the scent was appealing or off-putting, and how the serum felt on our skin. We also noted any irritation that occurred.

Based on our findings, we pared down our selection to our 11 favorite serums and one cream, which we feel are truly outstanding and accommodate a variety of skin concerns and price points.

What to Look for When Buying a Vitamin C Serum

When picking out a vitamin C serum, there are a few factors you’re going to want to take into account. Considering what kind of skin you have, what results you’re hoping to get, what additional ingredients a formula has, and how much you’re willing to spend will help you hone in on the perfect vitamin C serum for you.

Type of Skin

Derivatives are generally considered less irritating than pure vitamin C and better suited to sensitive skin. If your skin is particularly oily or dry, picking a serum that specifically suits your skin type may help. If you have normal skin that tolerates products well, you may want to pick something more powerful. You want to get the most effective serum for your skin type, without risking irritation.

Desired Results

All vitamin C serums primarily target evening out skin tone, but different formulations do cater to specific needs. If you’re looking to clear acne, fade scars, tighten your skin, or address dark spots, vitamin C can address all of these concerns. However, different serums may be better suited to target specific issues, depending on their individual formulations.

Additional Ingredients and Considerations

Ferulic acid is one of the best things you can add to a vitamin C serum, as it doubles its effectiveness.

Vitamin B3, or niacinamide, is sometimes rumored to weaken the effects of vitamin C, but most dermatologists agree this is actually a myth. Mixing stabilized vitamin C with niacinamide is great for repairing the moisture barrier and developing strong, healthy skin.

Specialty ingredients may be added to a product. Pay attention to the signature ingredients used in a formula and their impact on your skin. Ingredients like phloretin, green tea extract, caffeine, epidermal growth factor (EGF), and madecassoside, all of which appear on this list, are powerful ingredients in their own right and may have a significant impact on how your serum feels and affects your skin. If you’d rather keep it simple, there are also more basic serums that really focus on vitamin C as the sole hero ingredient.

Price can vary a lot. The serums on this list range from under $20 to close to $200, so getting a vitamin C serum can be an impulse Target buy or a serious investment. It’s nice to be able to try a clinically proven product like vitamin C at a low price point, but maybe you want to splurge and treat yourself to a high-end product that’s going to be a great way to pamper yourself every day. (You deserve it.)

What Is the Best Way to Incorporate Vitamin C Into My Skin Care Routine?

Apply vitamin C in the morning. Much of its benefit lies in protecting your skin from daytime stressors, including UV rays and other environmental factors, like pollution.

If you’re wondering how to best round out your skin care, a popular method for anti-aging has been coined the “CSA routine”: It involves applying a vitamin C serum in the morning, covering it with sunscreen, and then applying a retinoid (vitamin A) at night. “I like that, that’s perfect,” says Lamb of the CSA routine. She follows it herself, and “100 percent” recommends it to her patients.

What Effect Does Vitamin C Have on Skin?

Being a powerful antioxidant may be vitamin C’s main superpower, but it’s much more than a one-trick pony.

“It’s one of my favorite skin care ingredients because it has many benefits on the skin that are backed by scientific evidence. It is also a key ingredient for producing and maintaining collagen, supports immune and barrier function of the skin, and targets hyperpigmentation,” says He. With its long list of scientifically proven benefits, vitamin C is an easy, affordable way to step up your skin care routine.

Vitamin C’s primary effect is in evening skin tone, fading dark spots, and generally creating bright, luminous skin. It does have some impact on wrinkles and lines, but generally speaking, managing wrinkles is more of a retinol thing.

“I recommend vitamin C to many of my patients who want to brighten their complexion or address specific skin concerns like uneven skin tone, hyperpigmentation, age spots, sunspots, or dullness. I practice in New York City, where many of my patients are constantly exposed to pollution, tobacco smoke, and other sources of oxidative stress. Antioxidants like vitamin C play a key role in skin health and anti-aging,” says He.

Does the Type of Vitamin C in a Serum Matter?

Not very much, according to Lamb. “So, unlike retinols, where there’s a lot of data around which one binds to a particular receptor, a lot of (C-derivatives) are all about stability,” Lamb explains, rather than differing in function. “We don't have as much talk about like, ‘Oh, what type of vitamin C it is?’ Unlike, for example, a retinol, [where] we have more categories. It’s not as nuanced with the vitamin C.”

That said, L-ascorbic acid is pure vitamin C. It’s the strongest, most effective form of vitamin C available. About a dozen popular derivatives are used in skin care, and while none are as strong as L-ascorbic acid, they usually don’t vary too greatly in concentration, either.

According to an independent study from the skin care company Exponent, SAP and MAP are 58 percent as potent as L-ascorbic acid, and 3-0-ethyl ascorbic acid is 86 percent as effective. So, derivatives are weaker but still in the same ballpark.

FAQ

What ingredients shouldn’t I mix with vitamin C?

Avoid mixing vitamin C with other acids, such as alpha-hydroxy acids (AHAs), beta-hydroxy acids (BHAs), or retinol, as this can lead to irritation. If you’d like to incorporate these acids, apply them at night, after you’ve washed off your vitamin C serum.

According to He, “With vitamin C, patience and consistency are key. With consistent use, as the skin naturally turns over, most people will start seeing visible improvements at around 2 months.”

It does the opposite. Applying vitamin C in the morning will actually help protect your skin from the damaging effects of the sun. It does not block out the sun the way sunscreen does and should never be considered a substitute for sunscreen. However, when layered together, vitamin C can offer an additional source of protection from damaging free radicals, including UV rays, according to research


Yes, especially at higher concentrations. If you have sensitive skin, start with a serum or cream that contains a vitamin C derivative that’s good for sensitive skin, like MAP or 3-0-ethyl ascorbic acid. Start with a low concentration, closer to 10 percent than 20 percent. Also, avoid applying the serum too close to your eyes or on your eyelids until you know how well your skin tolerates it.

Why Trust Everyday Health

We independently investigate and recommend products and services we believe will enrich the lives of our readers and meet their specific needs. You can trust our reviews because we do the legwork for you. Read more about why you can trust us.

Mary Dennis

Author

Mary Dennis is a Singaporean American health and science writer based in New York. Her work has been published in the Beijinger, Nautilus, South China Morning Post, Motherly, and Verywell Mind.

Her interest in covering mental health increased after the pandemic revealed our society's increasing need for care and information about how to manage our emotional health. She is passionate about maternal mental health issues in particular, and is the founder of Postpartum Brain, a website designed to educate and encourage people to learn more about perinatal mental health issues.

Mary has a masters degree in science journalism from Columbia University.

Jacquelyn Dosal

Jacquelyn Dosal, MD

Medical Reviewer

Jacquelyn Dosal, MD, is a board-certified dermatologist practicing at The Dermatology House in Park City, Utah. Her areas of expertise include acne, rosacea, integrative treatments of inflammatory skin diseases, as well as laser treatment of the skin and injectables.

Dr. Dosal writes cosmetic questions for the certifying exams for the American Board of Dermatology. She is also the deputy editor for the American Academy of Dermatology's podcast, Dialogues in Dermatology.

Daniel Oakley

Fact-Checker

Daniel Oakley is a journalist, editor, and fact-checker. He has written, edited, taught, and produced media for Dow Jones, S&P Global, IHS Markit, Third Coast Studios Magazine, and 826 National.

Oakley's path has always been a health-and-wellness-focused one. A competitive triathlete and racing fundraiser for the Leukemia and Lymphoma Society, he also spends summer weekends as an ISA-certified surf instructor and Red Cross professional water rescuer with Laru Beya Collective in Rockaway Beach, which helps kids master and delight in their own backyard — the ocean. It has taught Oakley that “optimizing body and mind” flourishes precisely at the wellspring of community.

Nicole Bonaccorso

Nicole Bonaccorso

Editor

Nicole Bonaccorso is a writer and editor with more than 12 years of journalism experience. She has been writing for Everyday Health since 2025, and has also been published on NBCNews.com, Treehugger, Verywell, Mashable, and Upworthy, among other publications.

Nicole was also a senior editor at Weather.com for more than 11 years, covering everything from weather and climate change to health, science, and travel.

In addition to writing, Nicole has also found a passion in helping new parents reach their breastfeeding goals and is working towards becoming a certified breastfeeding specialist.

In her free time, Nicole enjoys hiking, camping, cooking, reading, and spending time outdoors with her two young sons, husband, and dog.

Ashley Rowe

Tester

Ashley is a health and education writer who has covered fitness, mental health, nutrition, parenting, and education topics in her writing.

She is also an educator who brings over 15 years experience teaching in early childhood education. She has written early childhood education blogs and newsletters, and developed curriculums based on the Nature Explore project. She has also helped develop nutritional guides for families and education centers in Southern California and spearheaded the implementation of physical fitness programs for children.

Ashley received her bachelor’s degree in liberal studies from the University of La Verne, where she focused on elementary education, educational policy, and curriculum design. Her work in education has led to multiple certifications, including Nature Explore Specialist for the Outdoor Classroom Project, NESTA Children’s Nutrition Specialist, and is an active member of the National Association for the Education of Young Children.

Before joining Everyday Health, she wrote for Verywell Mind, Verywell Health, Parents, and Verywell Family. As a mother of three young boys, Ashley splits her time between her career and her family.

Katie Tuttle

Tester

Katie Tuttle is an editor and writer specializing in food, nutrition, and product testing. Her work has appeared in EatingWell, Food & Wine, The Spruce Eats, and Real Simple. She has written about meal kits, kitchen tools, fitness, and wellness, and has tested and reviewed a wide range of products, with a particular focus on meal delivery services and their impact on nutrition and convenience.

Beyond food, Katie has covered fitness and wellness topics, drawing from her own experience as a powerlifter and an occasional runner. She’s always interested in how products and services can make healthy living more accessible and practical.

When she’s not researching or writing, Katie is usually surrounded by houseplants or spending time with a foster dog. She firmly believes there’s no such thing as too many books or too much coffee.

Mary Sauer

Tester

Mary Sauer is a freelance health and parenting writer whose work often covers mental health (especially maternal mental health), grief, and caregiving. Her work has been published by the Washington Post, Verywell Mind, Parents, Vice's Tonic, and ARC Poetry Magazine. She's also the managing editor of the upcoming Salt Tooth Press and an MFA student at University of Missouri, Kansas City.

Sauer is a mom of four and lives in Kansas City, Missouri. She enjoys hiking, trying new coffee shops, and shopping at used bookstores. At home, she spends her precious free time reading, rewatching Fleabag, and gardening.

Simone Scully

Tester

Simone Scully is the editorial director for service commerce and marketplace content at Everyday Health. She has nearly 15 years of experience as a professional health and science journalist, covering topics such as the psychological impacts of living with chronic conditions, nationwide gaps in menopause healthcare, grief, neonatal loss, and the latest wellness trends over her career. Her byline has been published by over 35 publications, including Healthline, Well+Good, InStyle, Psych Central, Romper, Narratively, Nautilus magazine, and more.

Before joining Everyday Health, Simone was an editorial director of health and parenting commerce and service content at Dotdash Meredith. She oversaw a team of editors and writers that published content across nine different sites, including the Verywells, Parents, Health, and Shape. Prior to this, she also worked as an editor at The Weather Channel's Weather.com, Upworthy, theSkimm, and Business Insider. A project Simone oversaw at Weather.com on the health and environmental impacts of global water shortages won several awards in 2020, including the CMA award for Best Series of Articles, an IAC award, and an Eppy award, among others.

Simone received a master's degree in Journalism from Columbia University's Graduate School of Journalism, where she focused on science and health long-form reporting and photojournalism. Her master's thesis explored the treatment of prolonged grief disorder following a miscarriage or the loss of a child. She was also awarded the John Horgan Award for Critical Science and Health Journalism at graduation.

Born in Minnesota, Simone lived 14 years in France until she graduated high school, then three years in London to get her bachelor's degree at the London School of Economics and Political Science. She currently lives in the Hudson Valley of New York with her husband, son, dog, and cats. When she's not working, you can find her writing fiction or plays, hiking in national parks, or tending to her garden and indoor plants.

EDITORIAL SOURCES
Everyday Health follows strict sourcing guidelines to ensure the accuracy of its content, outlined in our editorial policy. We use only trustworthy sources, including peer-reviewed studies, board-certified medical experts, patients with lived experience, and information from top institutions.
Resources
  1. Lin F et al. Ferulic Acid Stabilizes a Solution of Vitamins C and E and Doubles its Photoprotection of Skin. Journal of Investigative Dermatology. October 1, 2005.
  2. Anunciato Casarini TP et al. Dermatological applications of the flavonoid phloretin. European Journal of Pharmacology. December 15, 2020.
  3. Tuli HS et al. Phloretin, as a Potent Anticancer Compound: From Chemistry to Cellular Interactions. Molecules. December 12, 2022.
  4. Nesterov A et al. 1-(2,4-Dihydroxyphenyl)-3-(2,4-dimethoxy-3-methylphenyl)propane, a Novel Tyrosinase Inhibitor with Strong Depigmenting Effects. Chemical and Pharmaceutical Bulletin. 2008.
  5. Hakozaki T et al. The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer. The British Journal of Dermatology. July 2002.
  6. Nicotinamide. Memorial Sloan Kettering Cancer Center. February 21, 2023.
  7. Farris P.K.  "Cosmeceutical Vitamins: Vitamin C.". Procedures in Cosmetic Dermatology, Fourth Edition . April 25, 2024.
  8. Srivastava JK et al. Chamomile: A Herbal Medicine of the Past With Bright Future. Molecular Medicine Reports. November 1, 2010.
  9. Heggar Venkataramana S et al. Potential benefits of oral administration of AMORPHOPHALLUS KONJAC glycosylceramides on skin health – a randomized clinical study. BMC Complementary Medicine and Therapies. January 31, 2020.
  10. Ruamrak C et al. Comparison of clinical efficacies of sodium ascorbyl phosphate, retinol and their combination in acne treatment. International Journal of Cosmetic Science. February 2009.
  11. Kim E et al. Inflammation-modulating effects of an Albizia julibrissin Durazzini extract in an animal model of atopic dermatitis. South African Journal of Botany. May 1, 2025.
  12. An B et al. Physiological Activity of Irradiated Green Tea Polyphenol on the Human Skin. The American Journal of Chinese Medicine. January 2005.
  13. Al-Niaimi F et al. Topical Vitamin C and the Skin: Mechanisms of Action and Clinical Applications. The Journal of Clinical and Aesthetic Dermatology. July 1, 2017.
  14. Jacques C et al. Ascorbic acid 2‐glucoside: An ascorbic acid pro‐drug with longer‐term antioxidant efficacy in skin. International Journal of Cosmetic Science. December 2021.
  15. Pastore S et al. The Epidermal Growth Factor Receptor System in Skin Repair and Inflammation. Journal of Investigative Dermatology. June 1, 2008.
  16. Shin SH et al. The use of epidermal growth factor in dermatological practice. International Wound Journal. December 30, 2022.
  17. Dewi SR et al. The Comparison of the Effects of Caffeine Topical 0.25% and 0.5% as Anti-wrinkle Therapy. Proceedings of the 23rd Regional Conference of Dermatology. 2021.
  18. Desai S. How to Get Rid of Bags Under Your Eyes. Johns Hopkins Medicine.
  19. Tan SC et al. Actions and Therapeutic Potential of Madecassoside and Other Major Constituents of Centella asiatica: A Review. Applied Sciences. September 13, 2021.
  20. Al Abadie M et al. Topical Vitamin E in Modern Skin Therapy: A Comprehensive Review. International Journal of Clinical & Experimental Dermatology. December 12, 2024.
  21. Bravo B et al. Benefits of topical hyaluronic acid for skin quality and signs of skin aging: From literature review to clinical evidence. Dermatologic Therapy. October 21, 2022.