Psoriatic Arthritis and Hair Loss: Causes, Treatments, and Tips

Can Psoriatic Arthritis Cause Hair Loss?

Can Psoriatic Arthritis Cause Hair Loss?
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Psoriatic arthritis (PsA) is an autoimmune disease that causes inflammation of the joints, tendons, and nails. It usually occurs in people with psoriasis, an inflammatory condition causing rashes on the skin.

Symptoms can include joint pain, swelling, stiffness, and fatigue. Hair loss (alopecia) isn’t typically a sign of the disease, but it can affect some people with PsA in a roundabout way.

“Psoriatic arthritis and hair loss are not directly linked,” explains Jennifer E. Yeh, MD, PhD, a clinical assistant professor of dermatology at Stanford University School of Medicine in California. “However, having psoriatic arthritis may predispose one to hair loss from psoriatic arthritis inflammation, from psoriatic arthritis treatment, or from an increased likelihood of having another type of autoimmune condition.”

Physical or Psychological Stress Can Lead to Hair Loss

Psoriatic arthritis can significantly impact your emotional well-being, leading to anxiety, depression, diminished self-esteem — and particularly, stress. Chronic stress can worsen inflammation and immune dysregulation, leading to increased disease activity and more severe symptoms. Researchers note that stress may also disrupt neuroendocrine pathways, affecting cortisol levels and further dysregulating the immune system in PsA.

 According to the American Academy of Dermatology, stress is linked to hair loss and thinning hair.

Dr. Yeh says that both the physical and psychological stress associated with PsA can trigger a temporary type of hair loss called telogen effluvium.

With telogen effluvium, more hairs than normal are forced into their resting phase. When this happens, they fall out at once. Most people lose about 100 strands of hair a day. But if you have telogen effluvium, you may lose up to 300 strands a day.

“While telogen effluvium is characterized by an increase in daily hair shedding, it usually reverses, and hair regrows once the underlying stressor is removed,” Yeh says.

Medications for PsA May Cause Thinning Hair

Treatments for PsA can contribute to hair loss. Some common culprits are:

  • Methotrexate It stops cells from growing — including hair follicles. About 1 to 3 percent of people who use it experience hair loss.

  • Leflunomide This medicine works like methotrexate and causes hair loss in about 10 percent of people.

  • Anti-TNF Therapy Research has shown that “a sizable minority” of people on TNF inhibitors develop alopecia areata, the most common inflammatory hair loss disease, at a higher prevalence than the general population, though it’s not clear why this happens.

“Treatment-related alopecia typically improves with discontinuation of the offending medicine,” says Yeh.

Comorbid Psoriasis and Hair Loss

Most, but not all, people with PsA also have psoriasis.

And, if you have psoriasis, you have a 45 to 56 percent chance of developing scalp psoriasis.

Scalp psoriasis causes a dry, itchy, and inflamed scalp. “Scalp psoriasis that is not controlled irritates the hair follicles, disrupting normal hair follicle function, and thereby causing hair shedding,” says Yeh.

If you scratch or pick at the lesions, you can also damage hair follicles. This can result in additional hair loss.

The good news is that hair loss due to scalp psoriasis is usually temporary. “Most cases show complete hair regrowth after treatment,” says Yeh.

If you have severe psoriasis plaques, you should be aware that the oral medication acitretin, occasionally used to treat persistent psoriasis, can cause hair loss.

What to Do About Hair Loss

If you have PsA and experience hair loss, talk to your doctor. If you’re not already seeing a dermatologist to manage your condition, your rheumatologist can refer you to one who may be able to determine the underlying cause of your hair loss.

Getting your symptoms under control can also help preserve your hair. “Hair loss from uncontrolled PsA reverses once the inflammation is well-controlled,” says Yeh. “It’s critical to treat concomitant scalp psoriasis so that local inflammation surrounding hair follicles on the scalp does not contribute to increased hair shedding.”

Here are some ways you can help prevent hair loss caused by scalp psoriasis.

  • Try not to touch, pick, or scratch your scalp.
  • Keep your fingernails short.
  • Be gentle when brushing, combing, washing, or drying your hair.
  • Wear a hat when you’re outside.
  • Use a medicated shampoo that contains salicylic acid and follow with a moisturizing conditioner.
  • Don’t take extremely hot showers.
  • Ask your doctor about a prescription treatment that can help your symptoms.
  • Avoid blow-drying your hair. If you do, use a low-heat setting.
  • Try to keep stress levels low.
  • Follow a healthy diet.
  • Avoid heavy drinking.

While hair loss associated with PsA can be frustrating, the right treatments and lifestyle habits can help you minimize shedding — and protect the hair you have.

The Takeaway

  • If you have psoriatic arthritis and you’re experiencing hair loss, consult your doctor to determine the underlying cause and effective treatment strategies.
  • Medications such as methotrexate and leflunomide, commonly used to manage PsA, might contribute to hair thinning, so discuss potential side effects with your healthcare provider to explore any necessary adjustments.
  • Emotional and physical stress linked to PsA can cause temporary hair loss; reducing stress levels and effectively managing the disease can lead to regrowth and a healthier scalp condition.
  • If you’re dealing with scalp psoriasis, measures such as medicated shampoos and avoiding scalp irritation can prevent additional hair loss and support recovery.
EDITORIAL SOURCES
Everyday Health follows strict sourcing guidelines to ensure the accuracy of its content, outlined in our editorial policy. We use only trustworthy sources, including peer-reviewed studies, board-certified medical experts, patients with lived experience, and information from top institutions.
Resources
  1. Psoriatic Arthritis. Cleveland Clinic. September 19, 2023.
  2. Lubrano E et al. Psychological Health in the Management of Patients with Psoriatic Arthritis: An Intricate Relationship. Rheumatology and Therapy. March 25, 2025.
  3. Feeling stressed? It can show in your skin, hair, and nails. American Academy of Dermatology. July 21, 2022.
  4. Telogen Effluvium. Cleveland Clinic. December 1, 2022.
  5. Arthritis Medications and Hair Loss. Arthritis Foundation.
  6. Perez SM et al. Lessons from TNF-α Inhibitor–Induced Alopecia Areata: Does TNF-α Operate as a Hair Follicle Immune Privilege Guardian under Inflammatory Conditions? Journal of Investigative Dermatology. October 2025.
  7. Expert Q&A: PsA without Psoriasis? Arthritis Foundation.
  8. Scalp Psoriasis. National Psoriasis Foundation. October 30, 2025.
  9. Experiencing Scalp Psoriasis? Learn How to Treat and Reduce Hair Loss. Cleveland Clinic. April 16, 2024.
  10. Acitretin (Oral Route). Mayo Clinic. April 1, 2025.
  11. Zito PM et al. Acitretin. StatPearls. February 2024.

Oyetewa Asempa, MD, FAAD

Medical Reviewer

Dr. Oyetewa Asempa is an assistant professor of dermatology at Baylor College of Medicine, and the director of the Skin of Color Clinic for Baylor's department of dermatology. She was born and raised in Atlanta and then went on to graduate summa cum laude from Howard University in Washington, DC.

She completed her medical training at University of Illinois at Chicago College of Medicine, during which time she also completed a year of research at the National Institutes of Health. She completed her internship at George Washington University, and then her residency training at the Harvard dermatology program, where she served as chief resident in her final year.

She specializes in hair loss and scalp disorders, as well as pigmentary disorders in patients of color. She has spoken at multiple national conferences. Outside of medicine, she enjoys writing short stories, as well as writing and performing spoken word poetry.

julie-marks-bio

Julie Lynn Marks

Author

Julie Marks is a freelance writer with more than 20 years of experience covering health, lifestyle, and science topics. In addition to writing for Everyday Health, her work has been featured in WebMD, SELF, HealthlineA&EPsych CentralVerywell Health, and more. Her goal is to compose helpful articles that readers can easily understand and use to improve their well-being. She is passionate about healthy living and delivering important medical information through her writing.

Prior to her freelance career, Marks was a supervising producer of medical programming for Ivanhoe Broadcast News. She is a Telly award winner and Freddie award finalist. When she’s not writing, she enjoys spending time with her husband and four children, traveling, and cheering on the UCF Knights.