Symptoms and Diagnosis of Polycystic Ovary Syndrome (PCOS)

As a woman, dealing with acne, stray hairs, weight gain, and period problems seems like par for the course — and in some people’s minds, these are health woes that women just need to deal with. But a condition called polycystic ovary syndrome (PCOS) may really be behind these problems. And if you have PCOS, it’s important to get the right diagnosis for your current comfort and long-term health. Unfortunately, the reality is that several hurdles can make getting that diagnosis especially difficult.
Nonetheless, rather than referring to the condition as PCOS, experts now see it as a reproductive metabolic syndrome, says David A. Ehrmann, MD, an endocrinologist and clinical professor specializing in PCOS at the University of Chicago in Illinois. That’s because not everyone who has the condition has polycystic ovaries (the development of cysts, or fluid-filled sacs, in the ovaries).
The first step in understanding PCOS is learning about the signs and symptoms. Take a look at some of the most common ones, so you know if PCOS may be at the root of your health concerns.

Symptoms of PCOS
PCOS affects everyone a little differently. These are some of the most common symptoms to look for.
Irregular Periods
Difficulty Conceiving
Excess Hair Growth
Hair Loss
Acne
Unintended Weight Gain
Increased Risk of Mood Disorders
Insulin Resistance
Trouble Sleeping and Fatigue
How Is PCOS Diagnosed?
Usually, PCOS appears around early puberty, but it can develop in your teens or twenties, says Ehrmann. More unlikely is when the condition emerges later in life, such as in your thirties and forties, he notes. That said, significant hurdles stand in the way of getting a proper diagnosis.
If you have PCOS symptoms or feel like you may be at an increased risk of developing the condition, it’s important to make an appointment with your healthcare provider. They can conduct a physical exam, order imaging scans, discuss your symptoms, and help you understand your options for treatment.
What to Do Next
The first step that many people take if they suspect they have PCOS is meeting with an ob-gyn (for the menstrual irregularities). But Ehrmann also recommends getting an endocrinologist involved. You can do this by asking your primary care provider for a referral. While there are no tests to directly diagnose PCOS, it’s often a matter of elimination. “We have to exclude other causes that can give the same picture,” says Ehrmann. That includes hypothyroidism, high prolactin levels, and rare conditions like Cushing syndrome and acromegaly. Providers will often figure this out via blood and urine tests.
The Takeaway
- Polycystic ovary syndrome is becoming more common but is still heavily underdiagnosed, which is why learning the symptoms is key.
- Common symptoms of PCOS include irregular periods, infertility, excess hair growth or hair loss, acne, weight gain, and a higher risk of depression and anxiety.
- To get a diagnosis for PCOS, you must meet two of the following criteria: high levels of androgen, ovulatory dysfunction, or polycystic ovaries.
- If you suspect that you have PCOS or may be at risk for it, make an appointment with your healthcare provider to get referrals for an ob-gyn and endocrinologist.
Resources We Trust
- Mayo Clinic: Polycystic Ovary Syndrome (PCOS)
- Cleveland Clinic: PCOS, Anovulation, and Infertility
- Center for Young Women’s Health: PCOS (Polycystic Ovary Syndrome): General Information
- Planned Parenthood: Coping With PCOS
- PCOS Awareness Association: PCOS Health Complications
- PCOS Overview. PCOS Awareness Association.
- Polycystic Ovary Syndrome (PCOS). Johns Hopkins Medicine.
- Abnormal Menstruation (Periods). Cleveland Clinic. January 18, 2023.
- PCOS (Polycystic Ovary Syndrome) and Diabetes. Centers for Disease Control and Prevention. May 15, 2024.
- Hirsutism. Mayo Clinic. September 17, 2025.
- PCOS Symptoms. PCOS Awareness Association.
- Atakul N et al. Levels of a novel metabolic marker, spexin in patients with hirsutism: metabolic syndrome risk in idiopathic and polycystic ovarian syndrome (PCOS) hirsutism. Ginekologia Polska (Polish Gynecology). August 14, 2024.
- Have PCOS? Here’s Everything You Need To Know About Acne and Other Skin Symptoms. Cleveland Clinic. September 12, 2024.
- Dubé-Zinatelli E et al. The overlooked mental health burden of polycystic ovary syndrome: neurobiological insights into PCOS-related depression. Frontiers in Neuroendocrinology. July 1, 2025.
- Diabetes and Polycystic Ovary Syndrome (PCOS). Centers for Disease Control and Prevention. May 15, 2024.
- Acanthosis Nigricans. Mayo Clinic. April 30, 2025.
- PCOS and Fatigue. PCOS Awareness Association.
- What Is PCOS? PCOS Challenge.
- Diagnosing Polycystic Ovary Syndrome. NYU Langone Health.

Anna L. Goldman, MD
Medical Reviewer
Anna L. Goldman, MD, is a board-certified endocrinologist. She teaches first year medical students at Harvard Medical School and practices general endocrinology in Boston.
Dr. Goldman attended college at Wesleyan University and then completed her residency at Icahn School of Medicine at Mount Sinai Hospital in New York City, where she was also a chief resident. She moved to Boston to do her fellowship in endocrinology at Brigham and Women's Hospital. She joined the faculty after graduation and served as the associate program director for the fellowship program for a number of years.

Jessica Migala
Author
Jessica Migala is a freelance writer with over 15 years of experience, specializing in health, nutrition, fitness, and beauty. She has written extensively about vision care, diabetes, dermatology, gastrointestinal health, cardiovascular health, cancer, pregnancy, and gynecology. She was previously an assistant editor at Prevention where she wrote monthly science-based beauty news items and feature stories.
She has contributed to more than 40 print and digital publications, including Cosmopolitan, O:The Oprah Magazine, Real Simple, Woman’s Day, Women’s Health, Fitness, Family Circle, Health, Prevention, Self, VICE, and more. Migala lives in the Chicago suburbs with her husband, two young boys, rescue beagle, and 15 fish. When not reporting, she likes running, bike rides, and a glass of wine (in moderation, of course).