Ovarian Cancer and Alcohol: Is Drinking Safe?

Can You Drink Alcohol With Ovarian Cancer?

Can You Drink Alcohol With Ovarian Cancer?
Getty Images

Note: While research on alcohol is evolving, the World Health Organization says drinking less or not at all is better for your health.

Alcohol use in people with ovarian cancer hasn’t been studied much, so there aren’t clear, evidence-based guidelines on whether drinking is safe or how much, if any, is appropriate.

An occasional drink may be safe for some people with ovarian cancer, but many are better off avoiding alcohol, especially during treatment, says Laurie L. Brunette, MD, a board-certified gynecologic oncologist at City of Hope Orange County in Irvine, California. The answer also depends on how well your liver is working, your nutritional status, and how you’re feeling overall.

Alcohol can worsen cancer treatment side effects such as nausea, dehydration, mouth sores, and contribute to poor sleep.

 It may also interact with certain medications commonly used during treatment or slow recovery after surgery, Dr. Brunette says. Check with your oncology team before drinking to avoid complications that could interfere with your treatment or recovery.

How Alcohol Affects Ovarian Cancer

Alcohol use has been linked to the risk of developing many types of cancers, including possibly ovarian cancer.

 But “we don’t have strong evidence that an occasional drink causes an existing ovarian cancer to grow or spread,” says Brunette.
Even so, alcohol, especially with heavy or ongoing use, can weaken your immune system and contribute to inflammation and oxidative stress (cell damage caused by harmful molecules).

 These effects can create a more “tumor-friendly” environment in the body, says Ryan Matthew Kahn, MD, a gynecologic oncologist at Baptist Health Herbert Wertheim Cancer Institute in Miami, Florida. This means alcohol may interfere with the body’s normal defenses.

 But it’s not known whether an occasional drink has this effect on existing ovarian cancer.

“So while we can’t say ‘alcohol will make your ovarian cancer spread,’ it may work against some of the things your body and your treatments are trying to do,” Dr. Kahn says.

Does Alcohol Interact With Ovarian Cancer Treatment?

Alcohol can interact with many ovarian cancer treatments; the recommendation is to avoid it during active phases of care, including before surgery, during chemotherapy, and while on maintenance therapy, says Ami Vaidya, MD, a gynecologic oncologist and co-chief of the division of gynecologic oncology at John Theurer Cancer Center at Hackensack University Medical Center in New Jersey.

Before Surgery

Dr. Vaidya recommends avoiding all alcohol before surgery. “This is a matter of medical safety, as large quantities of alcohol can interfere with anesthesia,” she says. Your body may respond to these medicines differently when you drink, which may affect the type and amount of anesthesia you need during surgery.

 Drinking alcohol can also raise your risk of bleeding and slow wound healing, Kahn says.
Avoiding alcohol for about two to four weeks before surgery can help lower the risk of complications.

 Always discuss how much and how often you drink with your surgical team, as this information helps them plan your anesthesia safely.

If you drink heavily, meaning four or more drinks on any day or eight or more per week for women, talk with your healthcare team before stopping suddenly.

 After prolonged heavy drinking, quitting alcohol abruptly can trigger withdrawal, which can be serious and life-threatening, especially around the time of surgery.

During Treatment

It’s also recommended to avoid alcohol during active treatment, Vaidya says.

Many chemotherapy drugs used to treat ovarian cancer, including paclitaxel (Taxol), are processed by the liver, says Kahn. “Alcohol adds extra stress to an already hard-working liver and can potentially worsen side effects like nausea, fatigue, and neuropathy,” he says. Neuropathy is nerve damage that can cause numbness, tingling, or pain, usually in the hands and feet.

Similarly, targeted treatments, including poly (ADP-ribose) polymerase (PARP) inhibitors, such as olaparib (Lynparza) and niraparib (Zejula), can put stress on the liver, and drinking alcohol can worsen this effect, says Vaidya.

The drugs used to manage treatment side effects, including pain medicines, sleep medications, and certain nausea medications, may also interact with alcohol, Brunette says. For these reasons, it’s best to avoid alcohol during active treatment, and to check with your oncology team before drinking, even if the amount feels small.

Here’s how alcohol can interact with some common ovarian cancer treatments and supportive medications, according to Kahn and Vaidya:

Medication Class
Examples
Why Alcohol Can Be a Concern
Platinum chemotherapy
carboplatin (Paraplatin), cisplatin (Platinol)
May worsen neuropathy
Taxanes
paclitaxel, docetaxel (Taxotere)
May worsen neuropathy
PARP inhibitors
olaparib, niraparib
May add extra strain to the liver. May also make side effects like nausea and fatigue harder to manage
Antiangiogenic therapy
bevacizumab (Avastin)
May worsen high blood pressure, which is already a side effect of bevacizumab
Corticosteroids
dexamethasone (Decadron)
May increase the risk of stomach irritation
Antinausea medications
ondansetron (Zofran)
May increase dizziness or drowsiness, or make nausea or dehydration harder to manage
Benzodiazepines (used for anxiety or nausea)
lorazepam (Ativan)
Can cause severe sedation and dangerously slow breathing, and even death
Opioids
oxycodone (OxyContin), morphine (MS Contin), hydrocodone (Norco)
Can cause severe drowsiness, dangerously slow breathing, coma, or death

After Treatment

Once you’ve completed treatment and move into surveillance, meaning regular medical checkups to monitor for signs that the cancer has returned, Kahn says an occasional drink is generally considered lower risk than it is during active treatment.

The focus in this phase is reducing the risk of recurrence and second cancers, says Vaidya, and drinking becomes a more personal decision that depends on your health, preferences, and quality of life. But it should still be discussed with your oncologist. Bear in mind that “from a cancer-risk perspective, no amount of alcohol is considered completely safe,” she says.

There’s also a possibility that alcohol could influence recurrence or second cancers after treatment, though the evidence isn’t clear enough to say for certain.

If you do choose to drink after treatment, it should be in strict moderation, Vaidya says, and no more than one drink on any given day, and not every day.

Drinking alcohol after ovarian cancer treatment may still not be appropriate for everyone. Brunette says people with abnormal liver tests, lingering side effects, or who are taking medications that can interact with alcohol may need to continue avoiding it.

Are Some Alcoholic Drinks Safer for Ovarian Cancer Than Others?

Research has not shown any type of alcohol to be safer than another for people with ovarian cancer, Brunette says. Beer, wine, and spirits all contain the same active ingredient, alcohol (ethanol), so how much you drink generally matters more than the type of beverage you choose.

 The World Health Organization also notes that alcohol carries health risks even at low levels.

Alcohol isn’t something oncologists recommend, says Kahn, who also recognizes that some people will choose an occasional drink. If that’s the case, he offers these general pointers.

  • Choose light or low-alcohol beer, which may contain less ethanol per serving, though the carbonation may worsen bloating.
  • Opt for a small glass of wine, about 5 ounces (oz) — which is considered a standard drink — or less, to keep your intake to a minimum; some people find white wine easier on the stomach than red wine.
  • Try a wine spritzer, made by diluting wine with water. Since sparkling water can add to bloating, use still water instead, or skip the spritzer if carbonation bothers you.

Safe Drinking Practices for People With Ovarian Cancer

Even if your oncology team has previously said an occasional drink is okay, check with them again whenever your treatment, medications, laboratory results, or health changes, says Vaidya. She also recommends being honest about how much and how often you drink so your care team can give you advice based on your complete health picture.

If your oncology team says you can drink occasionally:

  • Keep your serving to no more than one standard drink on any day you drink, Kahn says. A standard drink is about 12 oz of regular beer, 5 oz of wine, or 1.5 oz of distilled spirits (about one “shot”).

  • Plan several days each week when you don’t drink any alcohol, notes Kahn.
  • Avoid binge drinking. For women, this generally means having four or more drinks within about two hours.

  • Avoid sugary cocktails, which may add to nausea or digestive discomfort, Kahn says.
  • Do not drink on the day of a chemotherapy infusion.

  • Avoid alcohol on an empty stomach, drink it slowly with food, says Vaidya, and don’t drink when you feel sick or more tired than usual.
  • Drink plenty of water before, during, and after having alcohol to help prevent dehydration, Kahn says.

Cancer treatment can change how your body responds to alcohol, Brunette says, so a drink you tolerated well before diagnosis may affect you differently during or after treatment. Stop drinking and contact your care team if you develop increased nausea, unusual fatigue, worsening neuropathy, or yellowing of your skin or eyes, which may be signs of a liver problem, says Kahn.

You can still enjoy social time without drinking. A nonalcoholic beer or wine, a mocktail, or fruit-infused water can be good alternatives.

Talk to your oncology team if you need help cutting back on alcohol or quitting. You can also reach out to the Substance Abuse and Mental Health Services Administration (SAMHSA) National Helpline at 800-662-HELP (4357) for resources near you.



Resources We Trust

EDITORIAL SOURCES
Everyday Health follows strict sourcing guidelines to ensure the accuracy of its content, outlined in our editorial policy. We use only trustworthy sources, including peer-reviewed studies, board-certified medical experts, patients with lived experience, and information from top institutions.
Resources
  1. Rock CL et al. American Cancer Society Nutrition and Physical Activity Guideline for Cancer Survivors. CA: A Cancer Journal for Clinicians. March 16, 2022.
  2. Alcohol Use and Cancer. American Cancer Society. November 3, 2025.
  3. VanThomme G. 11 Things to Know About Alcohol and Cancer. Cancer UT MD Anderson. April 22, 2024.
  4. Full Proof: Explaining How Alcohol Can Interfere With Sleep. Cleveland Clinic. January 30, 2025.
  5. Fanfarillo F et al. Alcohol Consumption and Breast and Ovarian Cancer Development: Molecular Pathways and Mechanisms. Current Issues in Molecular Biology. December 20, 2024.
  6. Tsermpini EE et al. Alcohol-Induced Oxidative Stress and the Role of Antioxidants in Alcohol Use Disorder: A Systematic Review. Antioxidants. July 15, 2022.
  7. Alcohol’s Effect on the Body. National Institute on Alcohol Abuse and Alcoholism. June 2025.
  8. Preparing for Surgery: Checklist. American Society of Anesthesiologists.
  9. Chapman L et al. Reducing Alcohol Use Before and After Surgery: Qualitative Study of Two Treatment Approaches. JMIR Perioperative Medicine. July 26, 2023.
  10. The Basics: Defining How Much Alcohol is Too Much. National Institute on Alcohol Abuse and Alcoholism. May 8, 2025.
  11. Jenkins MJA et al. Peri-Operative Identification and Management of Patients With Unhealthy Alcohol Intake. Anaesthesia. January 9, 2025.
  12. Peripheral Neuropathy. Cleveland Clinic. July 16, 2026.
  13. CARBOPLATIN- Carboplatin Injection, Solution. DailyMed. July 7, 2021.
  14. PACLITAXEL Injection Solution. DailyMed. July 2, 2026.
  15. LYNPARZA- Olaparib Tablet, Film Coated. DailyMed. July 10, 2025.
  16. AVASTIN- Bevacizumab Injection, Solution. DailyMed. January 6, 2025.
  17. Ondansetron (Oral Route, Oromucosal Route). Mayo Clinic. August 1, 2026.
  18. Alcohol-Medication Interactions: Potentially Dangerous Mixes. National Institute on Alcohol Abuse and Alcoholism. May 8, 2025.
  19. Alcohol. World Health Organization. June 28, 2024.
  20. About Standard Drink Sizes. Centers for Disease Control and Prevention. December 12, 2024.
  21. Understanding Alcohol Drinking Patterns. National Institute on Alcohol Abuse and Alcoholism. January 2026.
  22. Demarco C. 10 Things to Avoid While Receiving Chemotherapy. UT MD Anderson. January 4, 2023.
  23. Sobriety and Alcohol-Free Options. Baptist Health. March 18, 2025.
Emily Prendergast

Emily Prendergast, MD

Medical Reviewer

Emily Prendergast, MD, FACOG, is a board-certified gynecologic oncologist and associate professor at Cedars-Sinai Medical Center in Los Angeles, where she also serves as associate ...

Maggie-Aime-bio

Maggie Aime, MSN, RN

Author

Maggie Aime is a registered nurse with over 25 years of healthcare experience, who brings medical topics to life through informative and inspiring content. Her extensive nursing ba...