CLA vs. Carnitine

L-carnitine, also called carnitine, and conjugated linoleic acid (CLA) are naturally occurring compounds. They’ve become popular for their potential to reduce body fat and enhance athletic performance. But it’s important to understand the limitations of their effectiveness before working them into your routine.
What Is Carnitine?
Carnitine is a compound derived from amino acids, the building blocks of protein. Carnitine is essential for energy production in your body. It carries long–chain fatty acids to energy-producing mitochondria in your cells, and helps remove toxins to prevent them from building up, according to the National Institutes of Health (NIH) Office of Dietary Supplements (ODS).
Your liver and kidneys typically make all the carnitine you need from the amino acids lysine and methionine. But this compound also occurs naturally in some foods, particularly animal products.
Most people’s bodies can make enough carnitine. But people with certain conditions, like kidney dysfunction, may need to get carnitine from food or supplements.
Carnitine and Weight Loss
Because of its role in converting fatty acids into energy, carnitine has been marketed as a dietary supplement. But according to the ODS, research has found only a “possible modest reduction in body weight” from taking carnitine.
Carnitine and Athletic Performance
Carnitine supplements may help improve athletic performance.
In a review published in the journal Nutrients, researchers found that taking 3 to 4 grams (g) of L-carnitine 60 to 90 minutes before exercise could increase strength and endurance. However, this effect was only seen in high-intensity exercises.
Food Sources of Carnitine
Carnitine is found mostly in animal products and in smaller amounts in some plant-based sources. According to the ODS, foods high in carnitine include:
- Cooked ground beef, 3-ounce (oz) serving: 65 to 74 milligrams (mg)
- Whole milk, 1 cup: 8 mg
- Codfish, 3-oz serving: 3 to 5 mg
- Chicken breast, 3-oz serving: 2 to 4 mg
Experts haven’t set an upper-limit for carnitine intake. But consuming more than 4 g per day may cause nausea, vomiting, diarrhea, abdominal cramps, and a fishy body odor.
What Is Conjugated Linoleic Acid (CLA)?
CLA is a fatty acid found in dairy, beef, and lamb products. It may have benefits such as aiding weight loss, increasing exercise performance, and reducing inflammation, according to a review published in the journal Nutrition & Metabolism.
CLA and Weight Loss
Like carnitine, CLA is available in the form of supplements aimed at enhancing weight loss.
According to the ODS, research suggests that CLA may play a role in converting fat for energy, reducing fat storage, and promoting fat-cell turnover.
A randomized controlled trial published in the journal Nutrients found that women who were overweight or obese and took 3 g of CLA per day had significant reductions in total body fat after 12 weeks.
But in a review published in the journal Food Research International, researchers noted that the weight loss effects of CLA may be small, and that more studies are needed on people in the general population.
CLA Safety
CLA tends to be well-tolerated, according to the ODS. Although, like carnitine, CLA may cause minor side effects, such as abdominal discomfort, constipation, and diarrhea.
Best Supplements for Athletic Performance
According to ODS, most studies on the potential of supplements to enhance athletic performance do not include carnitine and CLA. Instead, they focus on more-common ingredients, like amino acids, protein, creatine, and caffeine.
While some supplements, particularly caffeine and creatine, may help improve endurance or strength, others show little evidence for their effectiveness.
Organizations like the American College of Sports Medicine recommend focusing on good nutrition through a well-rounded diet to improve performance instead of relying on supplements, according to the ODS.
For most adults, including athletes, the Dietary Guidelines for Americans describes a healthy dietary pattern as one that includes:
- A variety of fruits, vegetables, and whole grains
- Protein sources like lean meats, poultry, eggs, and legumes
- Low–fat dairy products like low-fat milk, yogurt, and cheese
- National Institutes of Health Office of Dietary Supplements: "Carnitine"
- National Institutes of Health Office of Dietary Supplements: "Dietary Supplements for Weight Loss"
- Nutrients: "Effect of Acute and Chronic Oral l-Carnitine Supplementation on Exercise Performance Based on the Exercise Intensity: A Systematic Review"
- Nutrients: "Body Fat Changes and Liver Safety in Obese and Overweight Women Supplemented with Conjugated Linoleic Acid: A 12-Week Randomised, Double-Blind, Placebo-Controlled Trial"
- Food Research International: "Conjugated linoleic acid (CLA) as a functional food: Is it beneficial or not?"
- MedlinePlus: "Nutrition and athletic performance"
- National Institutes of Health Office of Dietary Supplements: "Dietary Supplements for Exercise and Athletic Performance"
- U.S. Department of Agriculture and U.S. Department of Health and Human Services: "Dietary Guidelines for Americans, 2020-2025"
- Nutrition & Metabolism: "The effect of conjugated linoleic acids on inflammation, oxidative stress, body composition and physical performance: a comprehensive review of putative molecular mechanisms"

Lynn Grieger, RDN, CDCES
Medical Reviewer
Lynn Grieger is a registered dietitian-nutritionist, certified diabetes care and education specialist, certified personal trainer, and certified health and wellness coach. She completed requirements to become a registered dietitian at Valparaiso University in 1987 and completed a dietetic internship at Ingalls Memorial Hospital in Harvey, Illinois, in 1988.
Lynn brings her expertise in nutrition, exercise, and behavior change to her work in helping people reach their individual health and fitness goals. In addition to writing for Everyday Health, she has also written for websites and publications like Food and Health Communications, Today's Dietitian, iVillage.com, and Rodale Press. She has a passion for healthy, nutrient-dense, great-tasting food and for being outdoors as much as possible — she can often be found running or hiking, and has completed a marathon in every state.

Dylan Roche
Author
Dylan Roche has been a professional writer for more than 15 years. Since 2019, he has been an independent journalist and content creator focused predominantly on health and fitness, with work published by Livestrong, Health Digest, Our Health Magazine, School Nutrition Magazine, and What's Up Magazine, for which he serves as the contributing health editor.
When he's not writing, Roche can be found training for his next marathon or trying a new vegan recipe.