Should I Take Creatine in Pill or Powder Form?

Whether you’re a seasoned athlete or someone just getting into a workout routine, you may be interested in a supplement you can take to help improve your performance. One popular supplement is creatine — a chemical naturally found in your body that helps your muscles make energy, according to the Mayo Clinic.
While creatine is often praised by athletes and fitness influencers, there’s not a lot of high-quality research surrounding its effectiveness. In fact, most studies done on the supplement are small, outdated, or paid for by companies that make supplements.
That said, it’s still generally considered safe to use for most people, says the Mayo Clinic. Keep in mind that creatine supplements are not as strictly regulated by the FDA as prescription medications. When shopping, aim to find quality supplements that have been third-party-tested by brands like NSF, NSF for Sport, or ConsumerLab. And you should always talk to your doctor before trying any new vitamin or supplement.
Here, learn whether the pill or powder form of creatine is right for you, how to take it, and other safety tips to keep in mind.
Creatine Pills vs. Powder
Deciding between creatine pills and powder is largely about your personal preference.
If you have no problem swallowing a pill, taking creatine in this form can be a great way to make sure you’re getting the same amount each time. A typical pill may contain 2.5 grams (g) to 5 g of creatine per capsule, depending on the manufacturer.
On the other hand, creatine powder might be your preferred choice if you like to mix powders into your morning coffee, pre-workout smoothie, or just plain water. Powders tend to be more prevalent than pills, so this form may be easier to find. Typically, one tablespoon of powder contains 5 g of creatine.
Digestion time may be slightly different between the two forms of creatine. Your stomach has to break down a pill, which may take longer to digest than the powder itself or the powder mixed with other ingredients.
Convenience may also factor into your decision. You might prefer the ease of swallowing a premeasured pill as opposed to the potential mess of having to measure and mix the powdered creatine.
How to Take Creatine
When starting a creatine routine, some people load up with larger doses for the first few days. This loading phase involves taking 20 g to 25 g of creatine daily, breaking the doses up during the day, for five to seven days, says the Cleveland Clinic. Then, settle into a maintenance dose of 3 g to 5 g per day. The loading phase isn’t a good fit for everyone, however, and the Cleveland Clinic says you can skip this and instead start with the regular maintenance dose to limit side effects.
Creatine is available over-the-counter in pill, gummy, and powder forms. Take powdered creatine by mixing it in a beverage (such as juice, coffee, or water) or blending it in a fruit smoothie.
Adding powdered creatine to a shake or taking a pill with a snack or meal can help your muscles retain more of the creatine, according to the National Academy of Sports Medicine (NASM).
Make sure you’re drinking enough water while taking creatine for optimal results and to avoid dehydration. Look for light yellow urine to know you’re hydrated.
Although creatine is generally considered safe to use for up to five years in some studies, don’t take a higher dose than recommended, says the Mayo Clinic. There’s very little research looking at creatine use during pregnancy or breastfeeding, according to the Cleveland Clinic.
Those with kidney disorders should also talk with a doctor before trying creatine, which can worsen kidney issues. You should also talk to your doctor before trying creatine supplements if you have diabetes, liver disease, or bipolar disorder.
The Bottom Line
Whether you decide to take creatine in powder or pill form is largely up to your personal preferences, as long as you’re taking an appropriate dose.
Common Questions
If you follow a loading dose like the plan outlined above, you’ll saturate your muscles with creatine in five to seven days, according to the Cleveland Clinic. If you skip a loading dose and instead start with a maintenance dose, it may take closer to 21 to 28 days, says the NASM.
If you stop taking your pill or powdered creatine, your creatine levels will start to drop to the amount your body makes naturally, according to the Cleveland Clinic.
As your body adjusts, you might notice side effects such as:
- Decrease in muscle mass
- Weight loss
- Fatigue

Reyna Franco, RDN
Medical Reviewer
Reyna Franco, RDN, is a New York City–based dietitian-nutritionist, certified specialist in sports dietetics, and certified personal trainer. She is a diplomate of the American College of Lifestyle Medicine and has a master's degree in nutrition and exercise physiology from Columbia University.
In her private practice, she provides medical nutrition therapy for weight management, sports nutrition, diabetes, cardiac disease, renal disease, gastrointestinal disorders, cancer, food allergies, eating disorders, and childhood nutrition. To serve her diverse patients, she demonstrates cultural sensitivity and knowledge of customary food practices. She applies the tenets of lifestyle medicine to reduce the risk of chronic disease and improve health outcomes for her patients.
Franco is also a corporate wellness consultant who conducts wellness counseling and seminars for organizations of every size. She taught sports nutrition to medical students at the Albert Einstein College of Medicine, taught life cycle nutrition and nutrition counseling to undergraduate students at LaGuardia Community College, and precepts nutrition students and interns. She created the sports nutrition rotation for the New York Distance Dietetic Internship program.
She is the chair of the American College of Lifestyle Medicine's Registered Dietitian-Nutritionist Member Interest Group. She is also the treasurer and secretary of the New York State Academy of Nutrition and Dietetics, having previously served in many other leadership roles for the organization, including as past president, awards committee chair, and grant committee chair, among others. She is active in the local Greater New York Dietetic Association and Long Island Academy of Nutrition and Dietetics, too.

Jill Corleone, RD
Author
Jill is a registered dietitian and health writer based in Honolulu. She spent the early part of her career working in a traditional setting as a clinical dietitian in a hospital, then transitioned into management. Jill began her career as a health writer in 2007 while working as a clinical nutrition manager in Florida. She became a full-time writer in 2010 after the birth of her first child. Jill has written for numerous publications, including Livestrong; Eat This, Not That!; Fortune Recommends; Hone Health; and Diabetes Self-Management.

Sarah Klein
Author
Sarah Klein is a Boston-based health journalist with more than 15 years experience in lifestyle media. She has held staff positions at Livestrong, Health, Prevention, and Huffington Post. She is a graduate of the Arthur L. Carter Journalism Institute at New York University, and a National Academy of Sports Medicine–certified personal trainer. She moderated a panel on accessibility in fitness at SXSW in 2022, completed the National Press Foundation’s 2020 Vaccine Boot Camp, and attended Mayo Clinic’s Journalist Residency in 2019.