10 Symptoms of Menopause and Perimenopause

Menopause can arrive with a host of symptoms. Most women get at least some of these menopausal symptoms, typically when they’re in their late forties or in their fifties. But menopause can start earlier or later. Help is available, so reach out to your doctor if any of these symptoms cause problems for you.

1. Hot Flashes and Night Sweats
Causes
2. Slowed Metabolism and Weight Gain
Causes
3. Depression, Anxiety, and Mood Swings
Causes
Recognizing Symptoms of Perimenopause
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4. Insomnia and Sleep Disruptions
Menopause can wreak havoc on your ability to get quality shut-eye. Either you can’t fall asleep, or you wake up several times during the night.
Causes
- Levels of estrogen and progesterone, sleep-promoting hormones, are dropping.
- The sudden flash of heat and soaking perspiration from night sweats wakes you up. It may take a while to get back to sleep, especially if you have to change clothes and strip the bed.
- Depression and anxiety can both affect your sleep.
5. Hair Loss and Brittle Nails
Causes
6. Sexual Dysfunction, Desire Issues
Causes
7. Bone Loss and Osteoporosis Risk
Causes
The right supplements can help you navigate perimenopause. Read our comprehensive guide on the best supplements for perimenopause to find products that may help soothe your symptoms and support your overall health. Talk with your doctor before starting a new supplement, though.
8. Dry Skin and Other Skin Problems
Causes
9. Dry Eyes and Dry Mouth
Causes
A drop in estrogen also can lead to the drying of the oral mucosa in the same way it dries out the vagina.
10. Memory Issues and Problems With Concentration
Causes
The Takeaway
- Menopause can cause a variety of changes to your body that can lead to symptoms like hot flashes, weight gain, dryness, thinning hair, bone loss, and mood changes, among others.
- Other lesser-known symptoms can also happen during menopause, such as brain fog, dry mouth, and dry eyes.
- Menopause symptoms can range from mild to debilitating, but some women don’t seek help for relief due to stigma or lack of menopause awareness.
- If menopause symptoms are interfering with your quality of life, talk with your healthcare provider, who can provide lifestyle tips and guidance on treatment options.
Resources We Trust
- Mayo Clinic: Menopause
- Cleveland Clinic: Postmenopause
- The Menopause Society: Menopause Education for Patients
- American College of Obstetricians and Gynecologists: The Menopause Years
- Office on Women’s Health: Menopause Treatment
The right supplements can help you navigate perimenopause. Read our comprehensive guide on the best supplements for perimenopause to find supplements that will help soothe your symptoms and support your overall health.
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- Menopause Topics: Sexual Health. The Menopause Society.
- Sexual Difficulties in the Menopause. Australian Menopause Society.
- Vaginal Atrophy. Cleveland Clinic. April 10, 2023.
- Vaginal Atrophy (Atrophic Vaginitis). Harvard Health Publishing. February 12, 2024.
- Low Sex Drive in Women. Mayo Clinic. March 7, 2024.
- Osteoporosis. Cleveland Clinic. November 26, 2025.
- Postmenopause. Cleveland Clinic. July 30, 2024.
- Menopause Hormone Therapy: Is It Right For You? Mayo Clinic. April 18, 2025.
- The Things You’re Doing that Cause Wrinkles. The Ohio State University. August 13, 2024.
- Perimenopause, Menopause, and Dry Eyes. Johns Hopkins Medicine. September 30, 2025.
- Cardoso IL et al. Impact of Female Hormonal Changes Throughout Life on Oral Health: A Scoping Review. Journal of Dental Sciences. January 2026.
- Gorimanipalli B et al. Hormones and Dry Eye Disease. Indian Journal of Ophthalmology. April 2023.
- Shrivastava S. Menopause and Oral Health: Clinical Implications and Preventive Strategies. Journal of Mid-Life Health. October 17, 2024.
- Many Women Have Cognitive Issues During Menopause Author: Ask the Doctors. UCLA Health. September 29, 2021.
- Conde DM et al. Menopause and Cognitive Impairment: A Narrative Review of Current Knowledge. World Journal of Psychiatry. August 19, 2021.

John Paul McHugh, MD
Medical Reviewer
John Paul McHugh, MD, is an obstetrician-gynecologist and lifestyle medicine specialist in southern California. He has always placed wellness at the center of his work, in both delivering babies and improving practice standards. Dr. McHugh believes that bringing lifestyle medicine to the center of health and wellness empowers patients to make the change they seek and enjoy the benefits of true wellness.
He is a graduate of Harvard Medical School and the Massachusetts Institute of Technology and a fellow of the American College of Lifestyle Medicine. He served as a department chair at Scripps Mercy Hospital in San Diego and is now the chair-elect for the American College of Obstetricians and Gynecologists for California.
He has published several articles in the American Journal of Lifestyle Medicine and served as a peer reviewer for many articles. He contributed to the first textbook of lifestyle medicine in women's health: Improving Women's Health Across the Lifespan.

Beth Levine
Author
Beth Levine is an award-winning health writer whose work has appeared in The Washington Post, The New York Times, O: The Oprah Magazine, Woman's Day, Good Housekeeping, Reader's Digest, AARP Bulletin, AARP The Magazine, Considerable.com, and NextTribe.com. She has also written custom content for the Yale New Haven Hospital and the March of Dimes.
Levine's work has won awards from the American Academy of Orthopaedic Surgeons, the Connecticut Press Club, and the Public Relations Society of America. She is the author of Playgroups: From 18 Months to Kindergarten a Complete Guide for Parents and Divorce: Young People Caught in the Middle. She is also a humor writer and in addition to her editorial work, she coaches high school students on their college application essays.