Is Eating Low Fat or Low Carb Better for Heart Health? Trick Question

“There isn’t a one-size-fits-all diet but rather multiple pathways to achieving heart health when the focus is on quality,” says Grace A. Derocha, RD, CDCES, a Detroit-based spokesperson for the Academy of Nutrition and Dietetics.
Why Diet Quality Matters Most
- Healthy low-carb and low-fat diets both reduce the risk of heart disease.
- Low-carb and low-fat diets may contain unhealthy foods — bacon in a low-carb diet, for example, or snacks with added sugars in a low-fat diet — that are not dense in nutrients and could increase the risk of heart disease. These include foods with added fats and salt.
- Although the diets look very different on paper, your body responds to good versions of them in similar, heart-friendly ways.
This may explain why the debate between the benefits of a low-fat diet versus a low-carb diet has not had a clear winner.
“In practice, I see that when individuals focus on whole, minimally processed foods, their cholesterol, blood sugar, and inflammatory levels often improve, regardless of whether they identify as following a low-carb or low-fat diet approach,” Derocha says.
The reason? High-quality ingredients.
"Low-carb and low-fat diets that are considered healthy have similar characteristics,” says Sean Heffron, MD, a preventive cardiologist and the director of cardiovascular fitness and nutrition at the Center for the Prevention of Cardiovascular Disease at NYU Langone Health in New York City.
Both diets, Dr. Heffron says, are rich in potentially beneficial antioxidants and nutrients from these sources:
- Fruits and vegetables
- Whole grains
- Seafood
- Nuts
- Seeds
These higher-quality foods support heart health by improving key biomarkers such as lowering triglycerides, raising HDL (“good”) cholesterol, and reducing inflammation, says Zhiyuan Wu, PhD, a study co-author and postdoctoral research fellow at the Harvard T.H. Chan School of Public Health in Boston. This is largely because of the healthy fats, antioxidants, and anti-inflammatory compounds found in whole, plant-based foods, he says.
“Regardless of whether someone follows a low-carb or low-fat diet, choosing higher-quality foods helps the body regulate fat and inflammation more effectively, which likely explains the healthier biomarker profile we observed,” Dr. Wu says.
Conversely, you can easily find low-quality ingredients to eat within the framework of each diet. The secret, researchers say, is finding the balance between the positives of each approach.
Low Fat: Benefits and Risks
“Over time this can contribute to insulin resistance, elevated triglycerides, and increased inflammation, all of which are risk factors for heart disease,” Derocha says.
Low Carb: Benefits and Risks
- Lose weight
- Reduce triglycerides
- Lower blood pressure
- Increase HDL cholesterol
Where they can go wrong is in removing carbs in favor of saturated fat that increases LDL cholesterol and your risk of heart disease, Derocha says.
“They tend to entice people by telling them that since they aren’t eating carbs, they need to eat lots of protein and fat — and that means high saturated-fat foods like beef, pork, and bacon that people should be avoiding,” Heffron says.
Designing a Heart-Healthy Diet
“A heart-healthy approach doesn’t require choosing sides between carbs or fats,” Derocha says. “It’s about building a balanced, sustainable pattern centered on food quality.”
Here are the key strategies she recommends:
- Use whole, minimally processed foods as the foundation of your meals.
- Prioritize fiber-rich carbohydrates such as legumes, whole grains, vegetables, and fruits.
- Choose healthy fats, such as those found in nuts, avocados, and olive oil.
- Limit refined carbohydrates, added sugars, and highly processed foods.
- Incorporate lean protein sources, including fish and plant-based options like beans, soy, and seeds.
Always talk to your doctor and healthcare team before making any significant changes to your diet. Also note that with any healthy eating plan, consistency often matters more than perfection.
“Small, sustainable changes like swapping refined grains for whole grains or adding more vegetables to meals can have a meaningful impact on heart health over time,” Derocha says.
The Takeaway
- Low-carb and low-fat diets can be either healthy or unhealthy, depending on the quality of the foods you choose.
- Low-fat diets can be effective in removing unhealthy saturated fat, but the addition of refined carbohydrates in low-fat or nonfat foods may negate the diets’ positive effects.
- Low-carb diets such as Atkins, paleo, and keto can help you lose weight but may reintroduce animal fats that can pose cholesterol and heart risks.
- The quality of ingredients matters more than the amount of fat or carbohydrates you consume. Choose whole, minimally processed foods like fruits, vegetables, whole grains, lean protein, and healthy fats.
Resources We Trust
- Mayo Clinic: Low-Carb Diet: Can It Help You Lose Weight?
- American College of Cardiology: Healthy Versions of Low-Carb and Low-Fat Diets Linked to Better Cardiovascular and Metabolic Health
- American Heart Association: Saturated Fats
- Centers for Disease Control and Prevention: Preventing Heart Disease
- StatPearls: Low-Carbohydrate Diet
- Wu Z et al. Effect of Low-Carbohydrate and Low-Fat Diets on Metabolomic Indices and Coronary Heart Disease in U.S. Individuals. Journal of the American College of Cardiology Foundation. February 11, 2026.
- Banaszak M et al. Role of Omega-3 Fatty Acids Eicosapentaenoic (EPA) and Docosahexaenoic (DHA) as Modulatory and Anti-Inflammatory Agents in Noncommunicable Diet-Related Diseases – Reports From the Last 10 Years. Clinical Nutrition ESPEN. October 2024.
- Forty Years of Low-Fat Diets: A ‘Failed Experiment’. Harvard T.H. Chan School of Public Health. November 21, 2024.
- Saturated Fats. American Heart Association. August 23, 2024.
- Fats and Cholesterol. Harvard T.H. Chan School of Public Health.
- Saturated Fat. American Heart Association. August 23, 2024.
- Paoli A et al. Ketogenic Diet. StatPearls. January 2024.
- Volek JS et al. Expert Consensus on Nutrition and Lower-Carbohydrate Diets: An Evidence- and Equity-Based Approach to Dietary Guidance. Frontiers in Nutrition. February 29, 2024.
- Lei L et al. Effects of Low-Carbohydrate Diets Versus Low-Fat Diets on Metabolic Risk Factors in Overweight and Obese Adults: A Meta-Analysis of Randomized Controlled Trials. Frontiers in Nutrition. August 9, 2022.
- Ludwig DS. The Ketogenic Diet: Evidence for Optimism but High-Quality Research Needed. The Journal of Nutrition. June 2020.
- Popiolek-Kalisz J. Ketogenic Diet and Cardiovascular Risk – State of the Art Review. Current Problems in Cardiology. March 2024.
- Low-Carb Diet: Can It Help You Lose Weight? Mayo Clinic. January 21, 2026.

Maya Feller, MS, RD, CDN
Medical Reviewer
Maya Feller, MS, RD, CDN, is the founder and lead dietitian at Maya Feller Nutrition. In her practice, her team provides medical nutrition therapy and nutrition coaching for hormon...
