Microplastics Detox: Is It Possible?

Here’s what experts say about how long microplastics may linger in your body, if it’s possible to flush them out of your system, and potential strategies to minimize any damage these particles may cause.
Can You Detox From Microplastics You’ve Already Been Exposed To?
While additional evidence and larger studies are needed to expand on this theory, some experts say tactics like these won’t solve the issue of repeated microplastics exposure.
“If you're a human living in the modern world, you're going to be continually exposed to microplastics, and you could technically get your blood cleaned, but then as soon as you walk back out, you’re going to be re-exposed,” says Susanne Brander, PhD, an environmental toxicologist and an associate professor in the department of environmental and molecular toxicology at Oregon State University in Corvallis, whose laboratory researches the effects of microplastics and endocrine disrupting compounds on health. “There have been lots of articles published on how to reduce your exposure to microplastics — but you can’t reduce it completely. It’s just not possible.”
Steps You Can Take to Potentially Flush Out Microplastics
“I don’t think we necessarily know,” says Brander. There isn't any evidence to say one way or the other whether any strategy works comprehensively, and what effect a strategy has on reducing the risks linked to microplastics in the body. Read: If someone is trying to sell you a smoothie that’s supposed to eliminate microplastics, skip it.
- Boost your antioxidant intake. Initial research has pointed to the anti-inflammatory properties of antioxidants like anthocyanin (a plant compound found in purple and blue-hued foods like grapes and berries) as being helpful for reducing some of the hormonal and fertility-related effects of microplastics. The paper doesn’t give a specific amount of anthocyanins to consume.
- Eat a balanced diet. A diet rich in fresh fruits and vegetables, whole grains, legumes, and lean protein sources is a therapeutic recommendation for treating lead exposure, and may support your body overall in mitigating the harms from potential contaminants.
- Stay hydrated. Drinking a lot of water may not flush microplastics out of your body, but it does support your body’s natural detoxification process by helping your kidneys remove waste from the blood through urine. Avoid single-use plastic water bottles whenever possible.
Xiaobo Romeiko, PhD, an associate professor in the department of environmental health sciences at the University at Albany in New York, who researches chemicals found in plastic products, agrees that there aren't currently any proven ways to completely detox microplastics from the body, including commercially available cleanse and detox products.
“As far as I know, there is no clinical evidence that over-the-counter detox products can remove microplastics from the body,” Dr. Romeiko says. “However, eliminating exposure can be an effective strategy to reduce risk.”
Other Ways to Protect Yourself From Microplastics
Without specific scientific evidence around detoxing from microplastics, the best way to reduce their levels in our bodies is to limit exposure, says Abena BakenRa, MPH, a science associate at the UCSF Program on Reproductive Health and the Environment at the UCSF department of obstetrics, gynecology, and reproductive sciences in San Francisco, who has researched the effects of microplastic exposure on human health.
- Avoid microwaving food in plastic containers, as heat can trigger the release of microplastic particles.
- Use a filter for tap water, as certain water filters and treatments like reverse osmosis (RO) may reduce the presence of microplastics.
- Opt for glass containers, rather than plastic containers, for food and household items.
- Be selective with seafood consumption, as some shellfish may contain high concentrations of microplastics because of marine pollution. While there are a lot of variables at play when it comes to how many microplastics may be lurking in different types of seafood, one study suggests to shop for Chinook salmon, black rockfish, and lingcod.
- Switch out to a French press coffeemaker, or one with glass parts, rather than plastic varieties that could release microplastics with the presence of heat and water.
- Use household cleaning products that are part of the United States Environmental Protection Agency’s Safer Choice program. This federal program reviews products to ensure chemical ingredients, performance, and packaging are safe for human health and the environment.
Brander says these steps, rather than a single detox, will reduce any potential harmful health risks over the long-term.
“There’s no silver bullet, so to speak, and there’s no quick fix,” she says. “It's about revamping your lifestyle over time — and it doesn't have to be overnight. It doesn't have to be perfect, as long as you’re aiming to reduce microplastics exposure where you can.”
The Takeaway
- Microplastics are tiny plastic particles that humans are exposed to through diet, products, and the environment, with some research connecting them to a variety of potential health risks.
- While there currently isn’t enough specific scientific evidence about proven methods for detoxing from microplastics, dietary tactics like boosting antioxidant intake could support your body’s natural purification processes.
- Rather than focusing on detoxing, many experts suggest strategies that you can better control — like reducing your exposure to microplastics by avoiding single-use plastics — to potentially mitigate any harmful health risks.
- Impacts of Plastic Pollution. U.S. Environmental Protection Agency. May 2025.
- Lee Y et al. Health Effects of Microplastic Exposures: Current Issue and Perspectives in South Korea. Yonsei Medical Journal. May 2023.
- Bai C-L et al. Microplastics: A Review of Analytical Methods, Occurrence and Characteristics in Food, and Potential Toxicities to Biota. Science of the Total Environment. February 2022.
- Roslan NS et al. Detection of Microplastics in Human Tissues and Organs: A Scoping Review. Journal of Global Health. August 23, 2024.
- Yee MS-L et al. Impact of Microplastics and Nanoplastics on Human Health. Nanomaterials. February 2021.
- Lazaridis KN et al. Microplastics and Nanoplastics and the Digestive System. Gastro Hep Advances. May 2, 2025.
- Bornstein SR et al. Therapeutic Apheresis: A Promising Method to Remove Microplastics? Brain Medicine. May 2025.
- Apheresis. Cleveland Clinic. February 7, 2024.
- Wohlford L. Detoxes, Cleanses, and Fasts: What You Should Know. MD Anderson Cancer Center. April 2025.
- Gavin ML. Are Detox Diets Safe? Nemours Teens Health. January 2021.
- Actions to Reduce Potential Lead Exposure. U.S. Environmental Protection Agency. August 12, 2025.
- “Detoxes” and “Cleanses”: What You Need To Know. National Center for Complementary and Integrative Health. March 2025.
- Zhang J et al. Exploring the potential protective role of anthocyanins in mitigating micro/nanoplastic-induced reproductive toxicity: A steroid receptor perspective. Journal of Pharmaceutical Analysis. February 2025.
- Fight Lead Poisoning With a Healthy Diet. U.S. Department of Agriculture WIC Works Resource System.
- 6 Tips to be Water Wise for Healthy Kidneys. National Kidney Foundation.
- Chartres N et al. Effects of Microplastic Exposure on Human Digestive, Reproductive, and Respiratory Health: A Rapid Systematic Review. Environmental Science & Technology. December 2024.
- Toxic Matters. University of California San Francisco Program of Reproductive Health and the Environment.
- Corbett GA et al. Nutritional Interventions to Ameliorate the Effect of Endocrine Disruptors on Human Reproductive Health: A Semi-Structured Review From FIGO. International Journal of Gynecology and Obstetrics. February 2022.
- Top 5 Ways to Reduce Your Microplastics Exposure. Environmental Working Group. November 2024.
- How to Reduce Your Exposure to Microplastics. Blue Cross Blue Shield of Vermont. June 2025.
- Traylor SD et al. From the Ocean to Our Kitchen Table: Anthropogenic Particles in the Edible Tissue of U.S. West Coast Seafood Species. Frontiers in Toxicology. December 23, 2024.
- I’m a Microplastics Researcher. He’s how to Limit Their Dangers. University of California San Francisco. February 27, 2024.
- Learn About the Safer Choice Label. U.S. Environmental Protection Agency. September 11, 2025.

David Mannino, MD
Medical Reviewer
David Mannino, MD, is the chief medical officer at the COPD Foundation. He has a long history of research and engagement in respiratory health.
After completing medical training as a pulmonary care specialist, Dr. Mannino joined the Centers for Disease Control and Prevention (CDC) Air Pollution and Respiratory Health Branch. While at CDC, he helped to develop the National Asthma Program and led efforts on the Surveillance Reports that described the U.S. burden of asthma (1998) and COPD (2002).
After his retirement from CDC in 2004, Mannino joined the faculty at the University of Kentucky, where he was involved both clinically in the College of Medicine and as a teacher, researcher, and administrator in the College of Public Health. He served as professor and chair in the department of preventive medicine and environmental health from 2012 to 2017, with a joint appointment in the department of epidemiology.
In 2004, Mannino helped to launch the COPD Foundation, where he served as a board member from 2004 through 2015, chairman of the Medical and Scientific Advisory Committee from 2010 through 2015, and chief scientific officer from 2015 to 2017.
Mannino has over 350 publications and serves as an associate editor or editorial board member for the following journals: American Journal of Respiratory and Critical Care Medicine, Chest, Thorax, European Respiratory Journal, and the Journal of the COPD Foundation. He was also a coauthor of the Surgeon General’s Report on Tobacco in 2008 and 2014.

Cristina Mutchler
Author
Cristina Mutchler is an award-winning journalist with more than a decade of experience covering health and wellness content for national outlets. She previous worked at CNN, Newsy, and the American Academy of Dermatology. A multilingual Latina and published bilingual author, Cristina has a master's degree in Journalism from the E.W. Scripps School of Journalism at Ohio University.