Endometriosis Treatment: Medication, Lifestyle Changes, and More

Endometriosis Treatment: Medication, Lifestyle Changes, and More

Endometriosis Treatment: Medication, Lifestyle Changes, and More
Audrey Shtecinjo/Stocksy
Endometriosis is a chronic condition in which tissue similar to the uterine lining grows outside the uterus. Untreated endometriosis can have long-lasting effects, such as chronic pelvic pain, scar tissue, and infertility.

Appropriate endometriosis treatments depend on age, the severity of the symptoms and disease, and whether you may want to get pregnant. Consulting your doctor can help you find the best option for your situation.

Medication

The primary nonsurgical treatments for endometriosis are hormonal therapies and anti-inflammatories:

  • Nonsteroidal anti-inflammatory medication such as ibuprofen (Advil) and naproxen (Aleve) can help with pain management.
  • Birth control, including birth control pills, patches, and shots, as well as IUDs, may help control the hormones that worsen endometriosis.
  • Gonadotropin-releasing hormone (GnRH) therapies like elagolix (Orlissa) and leuprolide (Lupron) can control hormone levels and ease symptoms.
In some cases, typically after menopause, your doctor may prescribe aromatase inhibitors. These drugs can help lower your estrogen levels by preventing your body from turning androgens (like testosterone) into estrogen.

Surgery

Endometriosis causes excess tissue growth, and the body doesn’t have a way to clear it on its own. While medication may be able to help manage symptoms, if you’re experiencing severe pain, surgery may be necessary.

Laparoscopic Surgery

In many cases, endometriosis surgery is performed laparoscopically while you’re under general anesthesia. This requires only one or more small incisions near the navel, and a thin tube with a video camera can be inserted into the pelvis.

The tube also contains surgical instruments to remove lesions. Depending on the type of endometriosis you have, a surgeon may cut away or burn off tissue.

Usually, this can be done as outpatient surgery, but depending on the severity of the disease, you may need to spend a night in the hospital.

Hysterectomy

Hysterectomy is the surgical removal the uterus. This can help treat severe endometriosis symptoms, but it isn’t right for everyone. A hysterectomy will prevent future pregnancy and may have long-term health effects.

Can Endometriosis Symptoms Come Back After Surgery?

Endometriosis is a chronic condition that will recur unless the menstrual cycle is stopped. “After surgery, we commonly suppress recurrent endometriosis by starting continuous birth control pills,” says Leena S. Nathan, MD, a board-certified obstetrician-gynecologist at UCLA Health in Westlake Village, California. “This is safe and effective. The goal is to avoid having a period, which can lead to further implants and bleeding within the pelvis.”

Preventing periods can be accomplished with certain hormonal birth control methods and GnRH agonists and antagonists.

The ultimate therapy would be a hysterectomy and removal of one or both ovaries. And endometriosis symptoms overwhelmingly improve after patients transition through menopause, as the menstrual cycle has stopped.

Lifestyle Changes

If you have endometriosis, eating an anti-inflammatory diet may be helpful for managing symptoms:

  • Eat more fiber, available in fruits and vegetables.
  • Limit foods with trans and saturated fats, such as red meat and high-fat dairy.
  • Focus on fats with omega-3s, found in cold-water fish, tree nuts, seeds, and cold-pressed extra-virgin olive oil.
  • Avoid processed foods.
  • Get plenty of magnesium and zinc.
  • Stay hydrated and avoid caffeine, added sugars, and alcohol.

Complementary and Integrative Approaches

If you would like to try alternative remedies, discuss your choices ahead of time with your physician. Some of these may not be right for your particular situation or may interfere with your medication.

Do not forgo your traditional therapy for an alternative route. You can create a complementary route together as a team with your doctor.

According to research, these integrative approaches may offer some symptom relief:

  • Exercise Physical activity may help reduce pain and alleviate the side effects of medications.
  • Acupuncture This ancient traditional Chinese medicine practice may offer some pain relief.
  • Manual Therapy Physical therapists may help reduce pain through joint mobilization.
  • Electrotherapy Methods like transcutaneous electrical nerve stimulation can help decrease symptoms.
  • Cognitive Behavioral Therapy This helps address the mental health aspect of endometriosis symptoms.

The Takeaway

  • Endometriosis is a chronic condition that can cause significant pelvic pain and may affect fertility.
  • Treatments often include hormonal therapies and nonsteroidal anti-inflammatory drugs to manage symptoms, but surgery may be necessary for severe cases.
  • Dietary changes such as adopting an anti-inflammatory diet and limiting trans and saturated fats may offer some relief and support overall health.
  • It’s important to approach complementary and alternative therapies with care. Always consult your doctor beforehand to ensure safety and efficacy within your treatment plan.
EDITORIAL SOURCES
Everyday Health follows strict sourcing guidelines to ensure the accuracy of its content, outlined in our editorial policy. We use only trustworthy sources, including peer-reviewed studies, board-certified medical experts, patients with lived experience, and information from top institutions.
Resources
  1. Endometriosis. Mayo Clinic. September 16, 2024.
  2. Endometriosis. Johns Hopkins Medicine.
  3. Surgical Treatment of Endometriosis: Excision and Destruction. Brigham and Women’s Hospital.
  4. How To Follow a Healthy Endometriosis Diet and Why. Cleveland Clinic. June 16, 2025.
  5. Mazur-Bialy A et al. Holistic Approaches in Endometriosis - as an Effective Method of Supporting Traditional Treatment: A Systematic Search and Narrative Review. Reproductive Sciences. July 23, 2024.
kara-leigh-smythe-bio

Kara Smythe, MD

Medical Reviewer

Kara Smythe, MD, has been working in sexual and reproductive health for over 10 years. Dr. Smythe is a board-certified fellow of the American College of Obstetricians and Gynecologists, and her interests include improving maternal health, ensuring access to contraception, and promoting sexual health.

She graduated magna cum laude from Florida International University with a bachelor's degree in biology and earned her medical degree from St. George’s University in Grenada. She completed her residency in obstetrics and gynecology at the SUNY Downstate Medical Center in Brooklyn, New York. She worked in Maine for six years, where she had the privilege of caring for an underserved population.

Smythe is also passionate about the ways that public health policies shape individual health outcomes. She has a master’s degree in population health from University College London and recently completed a social science research methods master's degree at Cardiff University. She is currently working on her PhD in medical sociology. Her research examines people's experiences of accessing, using, and discontinuing long-acting reversible contraception.

When she’s not working, Smythe enjoys dancing, photography, and spending time with her family and her cat, Finnegan.

Beth Levine

Author

Beth Levine is an award-winning health writer whose work has appeared in The Washington Post, The New York Times, O: The Oprah Magazine, Woman's Day, Good Housekeeping, Reader's Digest, AARP Bulletin, AARP The Magazine, Considerable.com, and NextTribe.com. She has also written custom content for the Yale New Haven Hospital and the March of Dimes.

Levine's work has won awards from the American Academy of Orthopaedic Surgeons, the Connecticut Press Club, and the Public Relations Society of America. She is the author of Playgroups: From 18 Months to Kindergarten a Complete Guide for Parents and Divorce: Young People Caught in the Middle. She is also a humor writer and in addition to her editorial work, she coaches high school students on their college application essays.