How to Manage Eosinophilic Esophagitis During Allergy Season

If you have eosinophilic esophagitis (EoE), you may also have allergies, in the form of allergic rhinitis or food allergies. That’s not a coincidence. The two (or even three) conditions often coexist.
“Most people [with EoE] have a lot of allergies … or they’ve dealt with them in the past,” says Ashkan Farhadi, MD, a gastroenterologist at MemorialCare Orange Coast Medical Center in Fountain Valley, California. Moreover, allergies may exacerbate the symptoms of EoE.
Getting to the bottom of allergies and understanding how they affect your esophagus can help you sidestep more serious complications.
Why EoE and Allergies Are Linked
Experts suspect genetic or environmental factors play a role in the development of EoE. What is known, though, is that EoE can be caused by antigens (i.e., toxins) that trigger an overaction in the immune system. It’s common for these antigens to be food related, because the mucous membrane in the esophagus is so frequently exposed to food.
Common food allergen triggers for EoE include dairy, eggs, nuts, seafood, soy, and wheat, says Mary Ann Huang, MD, a hepatologist and gastroenterologist with HCA HealthONE Presbyterian St. Luke’s in Denver. Often, people are aware of allergens that make symptoms worse for them, she says. “In speaking to patients, they may point to a specific food that causes issues with dysphagia, or difficulty swallowing.”
What to Do for Allergies if You Have EoE
There are medical and lifestyle tweaks that can help manage both allergies and EoE symptoms.
First off, you’ll want to determine your trigger foods and then avoid them. “Elimination diets are often a first-line treatment,” says Dr. Huang. You’ll likely start by cutting out common allergens — eggs, nuts, soy — from your diet. Then, your gastroenterologist will do a biopsy of your esophagus to see if the inflammation is under control. If so, you may slowly reintroduce foods. Once you know your triggers, avoiding them entirely is best.
It’s also important to take steps to deal with environmental allergens if you have them, though this may have less of a direct impact on esophageal symptoms. Seeing an allergist to narrow in on the exact allergies you have is a good first step. Talk to them about whether you should get an allergy shot or take an antihistamine regularly.
If seasonal allergies tend to worsen EoE for you, check the pollen count in your area, and avoid the outdoors on days when it’s high. If possible, try to keep the windows closed — pollen can come in through an open window or door — and shower at night to remove pollen from your body before bed, so you’re not inhaling it all night.
Finally, talk to your doctor about the symptoms you’re having, to determine if the medications you currently take are adequate or if you need to make adjustments. EoE and its related conditions are quite varied and can turn critical quickly, so getting a correct diagnosis and treatment plan in place are key.
The Takeaway
- EoE and allergies often go hand in hand. Many people with EoE also have food or seasonal allergies, which can make esophageal symptoms worse.
- Triggers can vary, from foods to seasonal allergies. Common food allergens, such as dairy, eggs, soy, and wheat, can flare symptoms, but pollen and other airborne allergens may also play a role, especially during high-allergy seasons.
- Managing allergies can help protect your esophagus. Identify trigger foods, address environmental allergies, and work with your doctor on the right treatment plan to help keep inflammation under control and prevent complications.
- Atkins D. Aeroallergens in Eosinophilic Esophagitis: Significant Triggers or Noise in the System? Journal of Pediatric Gastroenterology and Nutrition. January 2017.
- Kliewer KL et al. One-Food Versus Six-Food Elimination Diet Therapy for the Treatment of Eosinophilic Esophagitis: A Multicentre, Randomised, Open-Label Trial. The Lancet Gastroenterology & Hepatology. May 2023.
- Eosinophilic Esophagitis. Cleveland Clinic. May 29, 2024.
- Eosinophilic Esophagitis. American College of Allergy, Asthma & Immunology. May 23, 2022.
- How to Effectively Manage Eosinophilic Esophagitis (EoE): A Guide to Diagnosis and Treatment. Allergy, Asthma & Immunology Medical Group.
- AAFA Calls Attention to Type 2 Inflammatory Diseases During National Asthma and Allergy Awareness Month. Asthma and Allergy Foundation of America. May 19, 2025.

Yuying Luo, MD
Medical Reviewer
Yuying Luo, MD, is an assistant professor of medicine at Mount Sinai West and Morningside in New York City. She aims to deliver evidence-based, patient-centered, and holistic care for her patients.
Her clinical and research focus includes patients with disorders of gut-brain interaction such as irritable bowel syndrome and functional dyspepsia; patients with lower gastrointestinal motility (constipation) disorders and defecatory and anorectal disorders (such as dyssynergic defecation); and women’s gastrointestinal health.
She graduated from Harvard with a bachelor's degree in molecular and cellular biology and received her MD from the NYU Grossman School of Medicine. She completed her residency in internal medicine at the Icahn School of Medicine at Mount Sinai, where she was also chief resident. She completed her gastroenterology fellowship at Mount Sinai Hospital and was also chief fellow.

Laurel Leicht
Author
Laurel Leicht has been a writer and editor for nearly two decades. A graduate of the College of William and Mary and the master's program at the Missouri School of Journalism, she covers a wide range of health and fitness topics, including breast cancer, various chronic conditions, mental health, and cardiovascular health.