How Bad Is It Really to Take Pepto-Bismol Every Day?

Pepto-Bismol can be just the thing to make a short-lived stomach bug or upset stomach more manageable.
But if you're relying on the pink liquid to keep gastrointestinal (GI) symptoms in check more often than not, is that a problem?
Here, learn if it's bad to take Pepto-Bismol every day, how much is too much, and when to see your doctor for GI issues that won't go away.
First, What's in Pepto-Bismol?
- Bismuth This chemical element works as an antiseptic to help fight off diarrhea caused by stomach bugs. "Most acute cases of diarrhea are caused by a short-lived bacterial or viral infection in the GI tract," says Aditya Sreenivasan, MD, a gastroenterologist at Northwell Lenox Hill Hospital in New York City. "Your body usually does a good job of clearing these infections within 24 to 72 hours, but bismuth can help shorten the length of symptoms," he adds. Bismuth also directly curbs diarrhea by reducing the amount of liquid secreted by the small intestine and increasing water absorption in the colon, making stools firmer.
- Subsalicylate This anti-inflammatory works a lot like aspirin. "It helps improve cramps and abdominal pain," Dr. Sreenivasan says.
Long-Term Effects of Taking Pepto-Bismol Every Day
That said, a daily dose of Pepto may not be the best idea for a few reasons.
1. It Could Mask a Larger Problem
If you find yourself needing to take bismuth subsalicyate for more than a few days, "it's likely you have an underlying issue that needs the attention of a doctor and some more definitive treatment," Sreenivasan says.
You could be dealing with stomach ulcers, irritable bowel syndrome (IBS), inflammatory bowel disease (IBD), celiac disease, or gallbladder or bile duct issues, he says. The only way to know for sure, though, is to see your doctor.
2. Large Doses Can Be Dangerous
"These aren't dangerous," Sreenivasan says, but can definitely be alarming if you're not expecting them. (You can avoid the black tongue by brushing your teeth and tongue well after each dose, especially if you take a dose before going to sleep.)
- Rapid breathing
- Lethargy
- Impaired cognition
- Vomiting
- Abdominal pain
Who Should Not Take Pepto-Bismol?
- Persistent vomiting
- Personality changes like irritability or combativeness
- Disorientation or confusion
- Convulsions
- You have a bleeding disorder.
- You have a GI condition that already causes black or bloody stools.
- You're taking certain medications like anticoagulants (blood thinners), sulfinpyrazone (for gout), probenecid or methotrexate (for arthritis).
So, How Often Should You Take Pepto-Bismol?
For healthy adults and teenagers who have stomach discomfort or diarrhea, the usual dose is 2 tablespoons (tbsp) every half hour to 1 hour if needed. You should not take more than 16 tbsp of the regular-strength suspension or 8 tbsp of the concentrate in 24 hours.
Alternatives to Pepto-Bismol
Fortunately, Pepto-Bismol isn't the only remedy for an upset stomach.
1. Give Your Stomach a Break
2. Apply Some Gentle Heat
Sometimes, a hot water bottle or heating pad placed over your stomach can be enough to ease abdominal cramping caused by gas, diarrhea, and GI upset.
3. Try an Herbal Remedy
Ginger and peppermint tea can quell a queasy stomach. And herbs like licorice (which can be found in tea blends) could even help reduce gas.
The Takeaway
- Pepto-bismol is a brand name for bismuth subsalicylate, an over-the-counter medication used to treat stomach upset.
- Taking Pepto-Bismol for a few days in a row, or even a week, likely won't hurt you, but if you need it every day for long stretches of time, you may have an underlying gastrointestinal issue that needs to be addressed.
- Talk to your doctor if you're unsure about your Pepto-Bismol use.
- Visit your doctor or the nearest emergency room if you experience other GI symptoms (regardless of whether you take Pepto-Bismol or not), including abdominal pain accompanied by fever, nausea, or vomiting; blood in your stool, urine, or vomit; abdominal swelling or tenderness; pain throughout your body or shortness of breath.
- Budisak P et al. Bismuth Subsalicylate. StatPearls. April 21, 2024.
- Is Pepto-Bismol Safe? National Capital Center Poison Control.
- Reye’s Syndrome. National Institute of Neurological Disorders and Stroke.
- Bismuth Subsalicyate (Oral Route). Mayo Clinic. July 1, 2025.
- Indigestion. Mayo Clinic. July 3, 2025.
- Weir SB et al. Bland Diet. StatPearls. July 25, 2023.

Waseem Ahmed, MD
Medical Reviewer
Waseem Ahmed, MD, is an assistant professor of medicine in the Karsh Division of Gastroenterology and Hepatology at Cedars-Sinai Medical Center in Los Angeles and serves as Director, Advanced Inflammatory Bowel Disease Fellowship and Education within the F. Widjaja Inflammatory Bowel Disease Institute.
He received his undergraduate degree from the University of Michigan and attended medical school at Indiana University. He then completed an internal medicine residency at New York University, followed by a fellowship in gastroenterology and hepatology at Indiana University, and an advanced fellowship in inflammatory bowel disease at the Jill Roberts Center for Inflammatory Bowel Disease at New York-Presbyterian Hospital/Weill Cornell Medicine. Prior to his current role, Dr. Ahmed served as an assistant professor of medicine within the Crohn’s and Colitis Center at the University of Colorado from 2021-2024.
Dr. Ahmed is passionate about providing innovative, comprehensive, and compassionate care for all patients with inflammatory bowel disease (IBD). His research interests include IBD medical education for patients, providers, and trainees; clinical trials; acute severe ulcerative colitis; and the use of combined advanced targeted therapy in high-risk IBD.
He enjoys spending time with his wife and dog, is an avid follower of professional tennis, and enjoys fine dining.

Marygrace Taylor
Author
Marygrace Taylor is an award-winning freelance health and wellness writer with more than 15 years of experience covering topics including women’s health, nutrition, chronic conditions, and preventive medicine. Her work has appeared in top national outlets like Prevention, Parade, Women’s Health, and O, The Oprah Magazine.
She's also the coauthor of three books: Eat Clean, Stay Lean: The Diet, Prevention Mediterranean Table, and Allergy-Friendly Food for Families. She lives in Philadelphia.