We Asked Dietitians Which Anti-Inflammatory Supplements They Recommend — Here’s What They Said

Overall, MegaFood Ashwagandha Complex delivers a comprehensive adaptogenic formula designed to support stress management and inflammation reduction.

Curcumin is an active turmeric compound responsible for many of its anti-inflammatory and health-supporting properties. We chose Thorne Curcumin Phytosome for its high-quality, easy-to-absorb formula.

We chose Nordic Naturals Ultimate Omega for its exceptional quality, sustainable sourcing, and potent omega-3 content. “My favorite omega-3 supplement is Nordic Naturals Ultimate Omega because it contains fish oil from wild-caught fish, meets strict purity standards from third-party testing, and is certified sustainable,” says Glinski. She adds that every Nordic Naturals product has its own certificate of analysis available, which verifies potency, purity, and freshness.

We love that this lemon-flavored product doesn’t taste fishy (or lead to the dreaded fish burps that some other products can). While the softgels may seem larger for some, Glinski says that the Ultimate Omega line also offers liquid and gummy forms. So folks who don’t like swallowing pills can still get the benefits.

“I appreciate how this garlic supplement is odorless (no garlic breath), comes in easy-to-swallow softgels, and is [Good Manufacturing Practices] GMP-certified for safety and quality,” says Mitri. “It is also free from many major allergens, such as gluten, wheat, yeast, milk, and lactose, as well as artificial flavors, sweeteners, colors, and preservatives.”

Garlic is often associated with garlic breath and body odor, especially in raw form. Nature’s Truth minimizes this issue with its odorless formula, although some users do report a subtle garlic odor, but not taste. Be aware that garlic can interfere with certain medications when taken as a supplement in high doses, so check with your doctor before starting. Overall, Nature’s Truth Odorless Garlic combines convenience, quality, and effectiveness into a budget-friendly option for reaping the health benefits of garlic.

Solaray Quercetin With Bromelain & Vitamin C also stands out for its affordability. “It’s a great value — around $26 for a month’s supply — making it a more affordable option compared to many other inflammation-focused supplements,” says Durston.

While the blend of ingredients is a significant strength, it may not appeal to those seeking a single vitamin C option. High doses of vitamin C can also cause an upset stomach for some people. However, we like the balance of ingredients that provides well-rounded support against inflammation and oxidative stress.

Life Extension Decaffeinated Mega Green Tea Extract earned its place as the best green tea supplement for its high dose and quality formula. Each capsule provides the equivalent of 3 cups (c) of green tea without the caffeine, delivering a concentrated dose without the stimulating effects.

We also like the quality and transparency of this product. “All Life Extension products are tested at various stages during the manufacturing process. Raw materials are analyzed for quality, while finished products are submitted to third-party testing organizations to confirm product purity and potency,” says Glinski. It’s also affordable and vegan-friendly, which makes it accessible for a wide range of diets and budgets, she says.

Although the decaffeinated formula is ideal for most users, some people who are looking for a slight energy boost might prefer a caffeine-inclusive alternative. Also, green tea extract can cause mild digestive upset in sensitive individuals if taken on an empty stomach. But overall, Life Extension Decaffeinated Mega Green Tea Extract is an all-around winner for those wanting to enjoy green tea’s anti-inflammatory and antioxidant powers without caffeine.

Durston emphasizes that the phytosome formula that enhances the bioavailability of this product, allowing your body to absorb and utilize its active compounds more effectively. “Plus, I trust Thorne for its strict third-party testing to ensure quality and safety,” she adds.

The benefits of Thorne Boswellia Phytosome come with few drawbacks. At $59 for 60 capsules, it’s a premium-priced option. But its superior absorption and quality assurance justify the higher cost. Overall, it’s an excellent choice for anyone seeking a high-quality, effective boswellia supplement.

“This product contains a generous 165 mg dose of bromelain and 800 mg of quercetin, another anti-inflammatory plant compound that gives this product an additional edge,” says Melissa Mitri, RD, nutrition writer and owner of Melissa Mitri Nutrition in Monroe, Connecticut.

Manaker also likes that this product is vegan-friendly, free from major allergens — like gluten, soy, dairy, and nuts — and is manufactured in a GMP-certified facility to ensure safety and quality.