Best Products for GLP-1 Digestive Side Effects
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GLP-1 Gut Check: Dietitian-Approved Products to Ease Digestive Side Effects

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Published on July 7, 2026
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There’s one thing I’ve noticed after working with people taking GLP-1 medications like Ozempic, Wegovy, and Zepbound. Those who have the best experience aren’t necessarily the ones who have the fewest side effects — they’re the ones who know how to manage them. While these medications can be incredibly supportive tools for weight loss, it’s not uncommon to experience digestive woes (especially in the beginning). From nausea and constipation to bloating and reflux, these side effects can surface quickly, but with the right tools, they’re often manageable.

That’s why I’m a big believer in having a GLP-1 “survival kit” on hand. Over the years, I've found myself recommending the same handful of products again and again. Here are a few of my favorite products to add to your GLP-1 gut-health survival kit.

Seed Daily Synbiotic supplement

Seed DS-01 Daily Synbiotic

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If I had to choose one product for supporting overall gut health — not just one symptom — a quality synbiotic would be near the top of my list. GLP-1 medications change how food moves through the digestive tract, and for some people, that can mean more bloating, reflux, or digestive discomfort. What I like about Seed’s Daily Synbiotic is that it combines prebiotics and probiotics to support the gut microbiome from multiple angles.

 

The capsule-in-capsule technology is especially impressive — it helps protect the beneficial bacteria as they travel through the stomach so more of them reach the intestines where they’re intended to work. As a dietitian, I’m also a fan of the company’s commitment to third-party testing and quality standards. When clients ask me for a probiotic recommendation, those are the kinds of details that matter.

The Ginger People Ginger Rescue

The Ginger People Ginger Rescue Lozenges

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Feeling nauseous is not fun, and it’s probably the GLP-1 side effect I most often see in clients. While dry snacks like pretzels or crackers can help, I often find ginger to be one of the most effective and convenient tools to have on hand. That’s why I often recommend the Ginger People Ginger Rescue Lozenges as a first line of defense when a queasy stomach strikes.

These tasty lozenges contain 800 milligrams (mg) of fresh ginger along with red ginger extract, and have a spicy-sweet flavor that makes them feel more like a treat than a supplement. I love that they can easily live in your purse, desk drawer, travel bag, or nightstand so they’re at your disposal whenever nausea decides to make an appearance. And let’s be honest, the adorable packaging doesn’t hurt either.

Psyllium husk powder

NOW Foods Psyllium Husk Powder

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If nausea is the most common GLP-1 complaint, constipation is a very close second. One of the biggest reasons? Many people simply aren’t eating as much food as they used to, which often means they’re getting less fiber without even realizing it.

 This is where NOW Foods Psyllium Husk Powder shines. With 7 grams (g) of fiber in just one tablespoon, it’s one of the easiest ways to help bridge this fiber gap.
I like recommending it because it’s affordable, manufactured by a company known for rigorous quality testing, and easy to customize based on your needs. Just remember that fiber and water are a team. Adding fiber without enough fluids is like adding more cars to a traffic jam — it won’t help things move any faster. And it’s super easy to slack on water intake on a GLP-1, since many people experience reduced thirst.

 To cover both bases, I encourage clients to gradually increase fiber while making hydration a daily priority.
Thorne Magnesium Citrate

Thorne Magnesium Citrate

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When fiber and hydration aren’t quite enough, magnesium citrate is often my next stop. Many of my GLP-1 clients find that adding magnesium as needed can help keep things moving comfortably without feeling overly aggressive. Some people taking GLP-1 medications may be at greater risk of magnesium deficiency, likely due to a combination of reduced food intake and absorption.

 Thorne’s Magnesium Citrate is one of my favorites because it’s third-party tested, mixes easily, and actually tastes good — a citrus berry flavor is a welcome change from some of the chalky supplements out there. There are many forms of magnesium, but magnesium citrate is one of the best for managing constipation and for its absorbability.

I appreciate the instructions to mix into 8–10 ounces (oz) of water, which creates a built-in hydration reminder. One important note: this isn’t necessarily a “more is better” situation. Magnesium citrate works best as a tool when needed, and taking too much can swing you from constipation to the opposite problem pretty quickly.

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Resources
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  2. Bocchio F, et al. Compendium of Bifidobacterium-based probiotics: characteristics and therapeutic impact on human diseases. Microbiome Research Reports. October 2024.
  3. Crichton M, et al. Effect of a Standardized Ginger Root Powder Regimen on Chemotherapy-induced Nausea and Vomiting: A Multi-center Double-blind Placebo-controlled Randomized Trial. Journal of the Academy of Nutrition and Dietetics. March 2024.
  4. Sanlier N, et al. From Husks and Seeds to Health: an Inevitable Outcome Rather than a Fluke. Current Nutrition Reports. February 2026.
  5. Winzeler B, et al. A randomized controlled trial of the GLP-1 receptor agonist dulaglutide in primary polydipsia. The Journal of Clinical Investigation. October 2021.
  6. Sibal R, et al. Macronutrient, Micronutrient Supplementation and Monitoring for Patients on GLP-1 Agonists: Can We Learn from Metabolic and Bariatric Surgery? Nutrients. November 2025.
  7. Zhang L, et al. Association of dietary magnesium intake with chronic constipation among US adults: Evidence from the National Health and Nutrition Examination Survey. Food Science & Nutrition. September 2021.