Protein and Cancer: Why It Matters and Tips to Optimize Your Intake

Why Protein Is Important During Cancer Treatment — and Tips to Optimize Your Intake

Why Protein Is Important During Cancer Treatment — and Tips to Optimize Your Intake
Everyday Health

Cancer and its treatments come with a lot to navigate. If you’re undergoing cancer treatment and have been told to get more sleep, exercise, or protein, it can feel very overwhelming — especially if you’re just trying to get through the day. Meeting basic nutrition goals may feel nearly impossible when you have no appetite, food tastes weird, or you’re dealing with constant nausea.

That said, it’s important to remember why protein matters. Cancer and cancer treatments like chemotherapy, radiation, and surgery cause protein to break down, so your body needs more of it to keep up. Protein gives your body the building blocks it needs to repair tissue, support immune function, maintain muscle mass, and protect against cancer-related cachexia (wasting syndrome) and physical stress.

Here are the protein sources to prioritize and tips to optimize your intake during cancer treatment and recovery.

How Much Protein Do You Need?

The latest dietary guidelines now recommend 1.2 to 1.6 grams per kilogram (g/kg) per day of protein for healthy adults.

 For people navigating cancer, this higher protein intake was the recommendation even before the guidelines changed. Protein intake greater than 1.4g/kg has been linked to better muscle mass preservation during cancer treatment, whereas eating less than 1.2g/kg was associated with muscle loss.


What does that look like in terms of food for the average adult?

For most adults, this translates to about 75 to 110 g of protein per day. For example, a person weighing 150 pounds (lb) may aim for 85 to 100 g per day. When spread across the day, this may end up being 25 to 30 g of protein per meal.

I recommend leaning toward plant sources of protein (more on that later). Here is what a plant-forward day of eating 90 g of protein could look like.

  • Breakfast A smoothie made with soy milk, banana, frozen berries, almond butter, and flaxseeds (Optional: plant protein powder to boost protein)
  • Lunch Lentil soup with roasted vegetables drizzled with olive oil and topped with hemp seeds (Optional: Blend in silken tofu for added protein)
  • Snack Options (High Protein and High Fiber) Soy or protein-fortified almond yogurt with chia seeds, roasted edamame, handful of nuts and seeds with an apple, or a protein bar with limited ingredients
  • Dinner Tofu stir-fry with vegetables over brown rice or quinoa

Why I Emphasize Plant Protein

As a lifestyle medicine physician, I can tell you that it’s not just about reaching a protein target — the protein source matters, too.

As mentioned in my last column, research consistently supports prioritizing plant-based proteins over animal-based proteins to improve cardiometabolic health, reduce cancer mortality, and support longevity.

 Plant proteins offer more than just protein. They are lower in saturated fat and rich in fiber, antioxidants, vitamins, and minerals.
What is especially amazing is that even a small shift can make a meaningful difference. Replacing even as little as 3 percent of your daily calories from animal protein to plant protein is associated with a lower risk of dying from cancer.

 And this can be as simple as one swap, such as replacing meat with lentils, tofu, or beans.

My Favorite Plant Proteins

My favorite plant protein is soy, and it deserves special attention for a reason.

Tofu provides about 20 g of protein per cup while edamame provides 18 g per cup, along with approximately 8 g of fiber.

 Whole soy foods, like edamame, tofu, and tempeh, are associated with a lower risk of breast cancer and lower recurrence in survivors.

Many cancer survivors may experience downstream effects of treatment such as metabolic changes, including high cholesterol or treatment-induced menopause, leading to symptoms like hot flashes. Soy has been shown to improve cholesterol levels and may help reduce vasomotor symptoms like hot flashes, making it a superstar plant protein in cancer survivorship.

Lentils are another protein staple I love and recommend. One cup provides roughly 18 g of protein and 16 g of fiber.

 Lentils are widely available, affordable, and easy to prepare. They can be blended into soups, sauces, and dips. And they are often easier to digest than other legumes, which can be especially helpful for someone dealing with side effects from treatment.

These are staples I rely on in my own kitchen to reduce my own risk of cancer, since I am a genetic mutation carrier.

Tips for Adding Protein When Eating Feels Hard

Some of the most common cancer treatment-related side effects are poor appetite, changes in taste, nausea, and vomiting. And sometimes, just the act of eating itself can feel overwhelming and exhausting.

Here are some strategies that worked well for my palliative care patients.

  1. Eat smaller portions, more frequently. These meals may look like heavy snacks rather than a full meal.
  2. Try smoothies or shakes to boost protein intake when appetite is low. You can make one at home with simple ingredients or buy a high-quality, plant-based option like Kate Farms. These premade shakes can be a practical and convenient way to support your protein, fiber, and essential nutrient needs when eating full meals feels difficult.
  3. Choose softer foods like soups, stews, purees, or oatmeal. These are easier to chew, swallow, and digest, and require less energy to eat, which can make a meaningful difference when dealing with fatigue and nausea.
  4. Use simple protein boosters anywhere: Add hemp or ground flaxseed to oatmeal, stir nutritional yeast into soups or pasta, add textured vegetable protein (TVP) to sauces or stews, keep roasted chickpeas or trail mix nearby, or spread nut butter on toast, fruit, or crackers.

Here’s What I Want You to Take Away

During cancer treatment and recovery, increasing your protein intake is about preserving lean muscle mass, maintaining strength, supporting your immune system, and protecting your quality of life. When you prioritize plant-based proteins, you get the added benefits of fiber, essential nutrients, and supporting long-term cancer risk reduction and longevity.

This season isn’t about perfection or an Instagram-worthy plate. It is about meeting your body where it is, even if that means you’re doing it with a smoothie, a bowl of soup, or just a handful of edamame at a time.

Important: The views and opinions expressed in this article are those of the author and not Everyday Health.

EDITORIAL SOURCES
Everyday Health follows strict sourcing guidelines to ensure the accuracy of its content, outlined in our editorial policy. We use only trustworthy sources, including peer-reviewed studies, board-certified medical experts, patients with lived experience, and information from top institutions.
Resources
  1. Dietary Guidelines for Americans, 2025–2030. U.S. Department of Agriculture. January 2026.
  2. Capitao C et al. Protein intake and muscle mass maintenance in patients with cancer types with high prevalence of sarcopenia: a systematic review. Supportive Care in Cancer. April 2022.
  3. Wang Y et al. Associations between plant-based dietary patterns and risks of type 2 diabetes, cardiovascular disease, cancer, and mortality – a systematic review and meta-analysis. Nutrition Journal. October 4, 2023.
  4. Budhathoki S et al. Association of Animal and Plant Protein Intake With All-Cause and Cause-Specific Mortality in a Japanese Cohort. JAMA Internal Medicine. August 26, 2019.
  5. Tofu, raw, regular, prepared with calcium sulfate. U.S. Department of Agriculture. April 1, 2019.
  6. Edamame, cooked. U.S. Department of Agriculture. October 31, 2024.
  7. Messina M et al. A Review of the Clinical and Epidemiologic Evidence Relevant to the Impact of Postdiagnosis Isoflavone Intake on Breast Cancer Outcomes. Current Nutrition Reports. March 25, 2025.
  8. Messina M et al. The health effects of soy: A reference guide for health professionals. Frontiers in Nutrition. August 11, 2022.
  9. Lentils, mature seeds, cooked, boiled, without salt. U.S. Department of Agriculture. April 1, 2019.
Reyna-Franco-bio

Reyna Franco, RDN

Medical Reviewer

Reyna Franco, RDN, is a New York City–based dietitian-nutritionist, certified specialist in sports dietetics, and certified personal trainer. She is a diplomate of the American Col...

Simran-Malhotra-bio

Simran Malhotra, MD

Author
Simran Malhotra, MD, DipABLM, CHWC, is a triple board-certified physician in internal medicine, hospice and palliative care, and lifestyle medicine, as well as a certified health a...