Chickenpox Treatment and Home Remedies

Chickenpox Treatment: Medication, Lifestyle Changes, and More

Chickenpox Treatment: Medication, Lifestyle Changes, and More
iStock; Everyday Health

Chickenpox, also called varicella, mostly affects children. But you can still get it as an adult if you’re exposed to the varicella-zoster virus and you don’t already have immunity from the chickenpox vaccine or from getting the disease in the past.

The standard treatment for chickenpox in children is simply watching and waiting for the disease to run its course, while taking proper home-care measures to ease the itching and other symptoms.

 Doctors usually prescribe antiviral drugs for adults and teenagers with chickenpox, because these groups of people tend to have more-severe symptoms and have a higher risk of complications.

If you have chickenpox or you think you might have it, talk with your doctor before starting any medication or remedy. Your doctor can do tests if needed and recommend the right treatment for you.

Medication

Sometimes, doctors may prescribe one or more medications for treating and managing chickenpox symptoms. If you’re thinking about trying any over-the-counter medications, talk with your doctor first. Certain medications, like aspirin, are off-limits when you have chickenpox (more on this below).

Medicines that your doctor may recommend include:

Antivirals

Your doctor may prescribe these if you’re at a high risk of getting severe complications from a chickenpox infection.

Your risk may be considered high if you:

  • Have a weakened immune system
  • Are pregnant
  • Are on immune-suppressing drugs
  • Have certain health conditions, like leukemia, chronic lung disease, or HIV/AIDS
Antivirals for treating chickenpox in these groups of people include:

These medications work best when you take them at the early stage of infection, preferably within the first 24 hours after rash symptoms appear.

So, act fast if you think you may have a high risk of complications from chickenpox: Call your doctor right away if you’re exposed to someone with chickenpox or if you get rash symptoms.

Pain Relievers

Experts recommend treating fevers or minor aches from chickenpox with acetaminophen (Tylenol).

“You should absolutely not use aspirin, as this can cause a rare complication known as Reye’s syndrome,” says Amy Edwards, MD, an assistant professor of pediatrics at Case Western Reserve University School of Medicine in Cleveland.

She says that the use of ibuprofen (Advil, Motrin) and other non-steroidal anti-inflammatory drugs (NSAIDs) is more controversial, as some studies have linked using these drugs when you have chickenpox to an increased risk of a bacterial skin infection.

However, Dr. Edwards says: “The data is marginal at best, and some doctors are still comfortable using them when needed with close supervision.”

Antihistamines

Oral antihistamines taken by mouth, such as dimetindene (Fenistil) and diphenhydramine (Benadryl) can be effective for relieving symptoms like itchiness linked with chickenpox.

 Diphenhydramine can induce sleep, which you may find helpful since the symptoms may cause restlessness.

It’s best to avoid topical antihistamines to go on the skin, including the topical form of diphenhydramine. These can trigger allergic reactions.

“In general, we recommend avoiding any medicated cream (antibiotic, antihistamine) on the skin,” Edwards says. She notes that this is because the skin is not intact in people with chickenpox, and you can absorb the medication into the deeper layers of your skin, where it isn’t meant to be. “This can cause a worse rash and in some people can ‘prime’ their skin’s immune system to react to that cream in the future, even when the chickenpox is gone.”

Immune Globulin

Varicella-zoster immune globulin (VZIG), particularly Varizig, is licensed for use in the United States for people exposed to chickenpox who cannot take the chickenpox (varicella) vaccine.

The U.S. Centers for Disease Control and Prevention (CDC) recommends that healthcare experts give VZIG to eligible people as soon as possible within 10 days after exposure to chickenpox.

People who may be eligible include:

  • Hospitalized premature babies whose mothers are not immune to varicella
  • Pregnant people without evidence of immunity
  • Those with compromised immune systems
While it protects against getting chickenpox after exposure to an infected person, VZIG can also help make symptoms less severe in people who’ve already developed the disease.

At-Home Remedies

“In truth, most ‘home remedies’ for chickenpox haven’t really been tested in a high-quality trial to really know if they are effective,” Edwards says. But it’s generally accepted that some of the home-based treatments may reduce the itching, pain, and discomfort linked with chickenpox, she says.

Also, many people with chickenpox don’t need medication, including children and adults without other health conditions whose symptoms aren’t severe. So, easing discomfort while the infection clears is important.

At-home remedies to ease discomfort include:

  • Apply cool compresses. Place a cloth soaked in cold water on painful or itchy areas. Leave it in place for a few minutes to an hour. This may ease discomfort and reduce the temptation to scratch.
  • Take cool baths. Soak in a bath of cool water with added elements, such as baking soda, rolled or ground oats, or a commercial oatmeal bath product. That can help ease the itching brought on by chickenpox. Both wet compresses and cool baths may be most effective at relieving itching when they’re done every three to four hours for the first few days of chickenpox symptoms.
  • Use calamine lotion. Apply dabs of calamine lotion to chickenpox blisters. It may reduce itching. Just be careful not to get it in your eyes.
  • Eat cold, soft, bland foods. Chickenpox sores in your mouth can feel awful, making it hard to eat and drink. You can minimize the discomfort by eating foods that aren’t too hot, are easy to chew and swallow, and don’t irritate your mouth. That means avoiding spicy, salty, and acidic foods.
  • Drink plenty of fluids. “Many children lose their appetite while sick, so I often tell parents not to worry if their child doesn’t want to eat, but to make sure to offer a wide variety of fluids, like water, juice, and soup”, says Casey Mabry, MD, a primary care physician at UM Baltimore Washington Medical Center in Glen Burnie, Maryland.

Also, Edwards says that for children and babies at low-risk of complications, the main concern is limiting scratching. That’s because scratching increases the risk of scarring and bacterial skin infections. It may be helpful for parents to have them wear gloves and to keep their fingernails trimmed short.

Lifestyle Changes

Aside from any steps taken to ease discomfort, you can take certain basic measures to help ensure that your chickenpox infection clears up as well as it can and doesn’t spread to others. These safety measures include the following:

  • Stay at home. Because chickenpox is so contagious, both adults and children with the disease should stay home from work or school until all blisters have broken and formed a crust.
  • Bathe regularly with soap and water. Keeping your skin clean reduces your risk of getting another skin infection. Be sure to pat, not rub, your skin dry after bathing to avoid irritation.
  • Wash your hands often. Keeping your hands clean reduces the risk that you’ll cause another infection by touching or scratching your skin.
  • Stay rested. Take it easy while you have chickenpox, especially if you have a fever or feel very tired. Resting can reduce stress on your body and help encourage healing.

Vaccination

“The chickenpox vaccine is the best way to prevent chickenpox,” Dr. Mabry says. “Since the vaccine became a part of the standard vaccine schedule in the early 1990s, chickenpox cases have decreased by about 97 percent.”

The CDC recommends two doses of the chickenpox vaccine for anyone — including children, teenagers, and adults — who has never had the disease or was never vaccinated.

However, pregnant people and individuals with a compromised immune system may not be considered eligible for the vaccination.

 Varicella-zoster immune globulin (VZIG) may be suitable for them, though.
“Two doses of the vaccine, given at 1 year old and 4 years old, are about 90-percent effective at preventing chickenpox infection,” Mabry says. She notes that people who haven't been vaccinated before can get a dose of the vaccine within three to five days of exposure and will still receive some protection from the vaccine.

The Takeaway

  • If you or your child has chickenpox, you can treat the symptoms at home with cool compresses, cool baths, and calamine lotion, as well as antihistamines and acetaminophen.
  • People with a high risk of complications from chickenpox — including teens and adults, pregnant people, and those with a weakened immune system — may be prescribed antiviral medications.
  • Talk to your pediatrician or doctor if you have any questions about your or your child’s chickenpox infection, including getting a vaccination for it.

Additional reporting by Joy Emeh.

EDITORIAL SOURCES
Everyday Health follows strict sourcing guidelines to ensure the accuracy of its content, outlined in our editorial policy. We use only trustworthy sources, including peer-reviewed studies, board-certified medical experts, patients with lived experience, and information from top institutions.
Resources
  1. Chickenpox - Diagnosis & Treatment. Mayo Clinic. April 19, 2023.
  2. How to Treat Chickenpox. Centers for Disease Control and Prevention. April 24, 2024.
  3. Clinical Guidance for People at Risk for Severe Varicella. Centers for Disease Control and Prevention. April 24, 2024.
  4. Quaglietta L et al. Serious Infectious Events and Ibuprofen Administration in Pediatrics: A Narrative Review in the Era of COVID-19 Pandemic. Italian Journal of Pediatrics. January 29, 2021.
  5. Parisi GF et al. Antihistamines in Children and Adolescents: A Practical Update. Allergologia et Immunopathologia. November-December 2020.
  6. Chickenpox. MedlinePlus. August 5, 2023.
  7. How to Care for a Child With Chickenpox. American Academy of Dermatology Association. August 17, 2022.
  8. Varicella-Zoster Immune Globulin. StatPearls. February 28, 2024.
  9. Saleh HM et al. Varicella-Zoster Virus (Chickenpox). StatPearls. April 27, 2025.
  10. Impact of U.S. Chickenpox Vaccine Program. Centers for Disease Control and Prevention. April 22, 2024.
  11. About Chickenpox. Centers for Disease Control and Prevention. April 24, 2024.
  12. Varicella Vaccine Recommendations. Centers for Disease Control and Prevention. July 15, 2024.
Michelle-Seguin-bio

Michelle Seguin, MD

Medical Reviewer

Michelle Seguin, MD, is a board-certified family medicine, lifestyle medicine, and certified functional medicine physician (IFMCP). She is a practicing physician at Root Functional Medicine, a leading telemedicine practice specializing in personalized, root-cause care.

Quinn Phillips

Author

A freelance health writer and editor based in Wisconsin, Quinn Phillips has a degree in government from Harvard University. He writes on a variety of topics, but is especially interested in the intersection of health and public policy. Phillips has written for various publications and websites, such as Diabetes Self-Management, Practical Diabetology, and Gluten-Free Living, among others.