Obstructive vs. Nonobstructive HCM: What’s the Difference?

Obstructive vs. Nonobstructive Hypertrophic Cardiomyopathy (HCM): What Your Diagnosis Means for Treatment and Lifestyle

Obstructive vs. Nonobstructive Hypertrophic Cardiomyopathy (HCM): What Your Diagnosis Means for Treatment and Lifestyle
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If you or a loved one has recently been diagnosed with hypertrophic cardiomyopathy (HCM), you may have questions about what it means for your health and how to manage the condition. Understanding whether your HCM is obstructive or nonobstructive can offer some more specific answers.

“The distinction matters for symptoms, risk assessment, and treatment decisions,” says Kevin Shah, MD, a board-certified cardiologist and program director of heart failure outreach at MemorialCare Heart and Vascular Institute at Long Beach Medical Center in Long Beach, California.

Explore what features set obstructive and nonobstructive HCM apart, the symptoms they can cause, and what it all means for your treatment plan.

Obstructive vs. Nonobstructive HCM: What’s the Difference?

The heart has four muscular sections, or chambers, that take blood in and pump it out to the rest of the body. Two of the chambers, called atria, sit on top. The other two, called ventricles, sit on the bottom. The chambers are connected by valves that open and close, allowing blood to flow through.

HCM is a heart condition that occurs when the walls of the left ventricle become thick and stiff, making it harder for the heart to fill with blood and send blood out. There are two types of HCM:

  • Obstructive HCM Parts of the heart wall block or limit blood flow from the left ventricle to the aorta, the artery that carries freshly oxygenated blood to other parts of the body. Two-thirds of people with HCM have the obstructive type.
  • Nonobstructive HCM The heart wall is thickened, but blood flow out of the heart isn’t blocked.

Knowing which type of HCM you have is important, since both need to be treated and managed differently. “Ideally, every patient with hypertrophic cardiomyopathy should be told whether it’s obstructive or nonobstructive,” says Karishma Patwa, MD, a board-certified cardiologist at Manhattan Cardiology in New York City.

If your cardiologist hasn’t told you, it’s worth asking. If they’re unsure — obstructions aren’t always detectable in tests when you’re at rest — they can conduct additional tests, such as an exercise stress test, to confirm whether you have an obstruction, says Dr. Patwa.

Graphic titled obstructive vs. nonobstructive hypertrophic cardiomyopathy (HCM). Definition under obstructive HCM is thickened heart muscles, leading to partially blocked blood flow and under nonobstructive hcm, thickened heart muscles, but blood flow is
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Symptoms

Many people with HCM will not experience symptoms, but obstructive HCM does increase their likelihood. When HCM does cause symptoms, you may experience:

  • Chest pain
  • Dizziness
  • Fatigue
  • Heart palpitations
  • Lightheadedness or fainting
  • Shortness of breath

You may be more likely to have these symptoms if you have obstructive HCM, especially when you’re dehydrated or physically active, says Dr. Shah. “Nonobstructive HCM can still cause symptoms, but they may be more subtle or gradual,” he says.

Treatment

There’s no cure for HCM, but treatment can help you feel your best and reduce your risk of complications.

“In obstructive HCM, treatment focuses on reducing the outflow obstruction and calming excessive contraction of the heart,” says Shah. “In nonobstructive HCM, treatment is more focused on managing stiffness, rhythm issues, and symptoms rather than relieving obstruction. The underlying goals overlap, but the strategies differ.”

No matter which type of HCM you have, discuss the benefits and drawbacks of an implantable cardioverter-defibrillator (ICD) with your cardiologist. The device is implanted under your skin to monitor your heart rate. It delivers an electric shock if it senses an irregular heart rhythm that could lead to sudden cardiac death.

While ICDs aren’t the right choice for everyone, the devices are more commonly used in people with obstructive HCM.

Symptom-reducing medications, such as beta-blockers and calcium channel blockers, can also be helpful for obstructive and nonobstructive HCM. Your cardiologist can recommend what may be best for you based on your symptoms and their severity.

You may be a candidate for additional medications or surgical procedures if you have obstructive HCM.

 Mavacamten (Camzyos) is an oral myosin inhibitor that targets the underlying cause of obstructive HCM. The drug can ease symptoms and help your heart function better.

Surgery options include:

  • Septal Ablation This procedure involves injecting alcohol into the thickened part of the heart in an effort to shrink it, and placing a catheter in an artery to maintain blood supply to that area of the heart.
  • Septal Myectomy This open-heart surgery involves removing a thickened part of the heart wall to improve blood flow out of the heart.

Each treatment option comes with benefits and risks, so consult your doctor to determine which one may be best for you.

Lifestyle

You may need to adjust your lifestyle when you have HCM, particularly if you have the obstructive type.

“Anything that reduces your cardiac output — the volume of blood your heart can pump per minute — can worsen obstructive HCM,” says Patwa. To manage your symptoms and reduce your risk of complications, Patwa and Shah say you may need to:

  • Avoid getting overheated
  • Drink plenty of fluids to prevent dehydration
  • Exercise caution if you take medications like diuretics or vasodilators (your healthcare provider will monitor you closely if they prescribe them)

Healthy habits matter, too. While they won’t necessarily improve HCM, eating a heart-healthy diet and getting regular exercise can help you feel your best overall and reduce your risk of other heart problems like heart disease, says Shah.

Vigorous exercise can make HCM symptoms worse, but if you have good symptom control, it’s likely safe to enjoy low-impact exercise, like walking.

 Check with your cardiologist before getting started, as they can help you determine a safe level of activity for you.
Finally, it’s important to get enough sleep, limit your alcohol consumption, and avoid smoking, as well as work with your doctor to manage any coexisting conditions, like high blood pressure or diabetes. These efforts can also go a long way toward limiting your symptoms and protecting your heart.

The Takeaway

  • Hypertrophic cardiomyopathy (HCM) is classified as either obstructive (when blood flow in the heart is partially blocked) or nonobstructive (when the heart is stiff but blood flow isn’t blocked).
  • While both types share symptoms like chest pain, fatigue, and shortness of breath, obstructive HCM is more common, and symptoms are often more severe during physical activity or when you’re dehydrated.
  • Treatment for obstructive HCM focuses on relieving the physical blockage through specialized medications or surgical procedures. Nonobstructive HCM treatment focuses primarily on managing heart stiffness and rhythm issues.
  • Lifestyle management for both types involves staying hydrated, avoiding overheating, and engaging in doctor-approved, low-impact exercise to protect heart health and prevent complications.

Resources We Trust

EDITORIAL SOURCES
Everyday Health follows strict sourcing guidelines to ensure the accuracy of its content, outlined in our editorial policy. We use only trustworthy sources, including peer-reviewed studies, board-certified medical experts, patients with lived experience, and information from top institutions.
Resources
  1. Heart. Cleveland Clinic. January 26, 2024.
  2. Hypertrophic Cardiomyopathy. American Heart Association. May 29, 2024.
  3. Obstructive Hypertrophic Cardiomyopathy. National Organization for Rare Disorders. July 27, 2024.
  4. Valzania C et al. Cardiac Implantable Electrical Devices in Patients With Hypertrophic Cardiomyopathy: Single Center Implant Data Extracted From the Swedish Pacemaker and ICD Registry. Scandinavian Cardiovascular Journal. August 2020.
  5. Bello J et al. Mavacamten. StatPearls. August 21, 2024.
  6. Hypertrophic Cardiomyopathy. Mayo Clinic. February 23, 2024.
  7. Fitness in HCM. Hypertrophic Cardiomyopathy Association. January 14, 2022.
  8. Lifestyle Steps When Managing Hypertrophic Cardiomyopathy. Mayo Clinic. April 7, 2025.
chung-yoon-bio

Chung Yoon, MD

Medical Reviewer
Chung Yoon, MD, is a noninvasive cardiologist with a passion for diagnosis, prevention, intervention, and treatment of a wide range of heart and cardiovascular disorders. He enjoys clinical decision-making and providing patient care in both hospital and outpatient settings. He excels at analytical and decision-making skills and building connection and trust with patients and their families.
Marygrace Taylor

Marygrace Taylor

Author

Marygrace Taylor is an award-winning freelance health and wellness writer with more than 15 years of experience covering topics including women’s health, nutrition, chronic conditions, and preventive medicine. Her work has appeared in top national outlets like Prevention, Parade, Women’s Health, and O, The Oprah Magazine.

She's also the coauthor of three books: Eat Clean, Stay Lean: The Diet, Prevention Mediterranean Table, and Allergy-Friendly Food for Families. She lives in Philadelphia.